Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: 9,10 diHOME Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 0.2510.101 0.02 0.014 0.122 0.099 0.014 0.013 0.083 0.088 0.057 0.049 0.136 0.069 0.073 0.051 0.052 0.032 0.084 0.044 0.039 - - 0.024 0.001 0.042 0.083 0.064 0.033 0.019 0.02 0.02 0.022 0.011 0.117 0.061 0.087 0.016 0.015 0.018 0.013 - - 0.483 0.337 0.05 2.54 0.881 12 9.54 9.38 0.798 31.1 2.68 1.62 4.43 1.4 2.59 4.62 5.29 12.1 4.34 19.8 9.49 1.24 - 0.236 0.148 0.387 0.036 8.98 44 5.1 - 9.05 0.09 0.218 5.5 - - 0.095 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA01050350 9,10 diHOME - 0.02 - 0.02 0.02 0.01 0.02 0.02 0.02 0.01 0.02 0.02 0.03 0.03 0.01 0.02 0.03 0.03 0.03 0.02 0.01 0.02 0.01 0.01 0.01 0.03 0.01 0.01 0.01 0.02 0.01 0.01 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA01050350 9,10 diHOME - 0.03 - 0.03 0.05 0.03 0.03 0.02 0.02 0.03 0.03 0.02 0.03 0.02 0.02 0.02 0.03 0.02 0.03 0.03 0.02 0.02 0.02 0.02 0.03 0.01 0.01 0.01 0.02 0.02 0.01 0.02 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA01050350 9,10 diHOME - 0.2 - 0.2 0.23 0.1 0.22 0.13 0.25 0.12 0.21 0.22 0.24 0.27 0.14 0.24 0.22 0.25 0.23 0.18 0.11 0.22 0.14 0.15 0.1 0.25 0.14 0.15 0.12 0.17 0.1 0.11 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA01050350 9,10 diHOME - 0.22 - 0.28 0.41 0.27 0.27 0.22 0.19 0.3 0.3 0.23 0.23 0.22 0.24 0.22 0.23 0.13 0.28 0.21 0.2 0.21 0.24 0.21 0.25 0.1 0.11 0.14 0.2 0.19 0.11 0.2 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 9,10 diHOME pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 9,10 diHOME pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 9,10 diHOME pmol/ml of medium Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) 9,10 diHOME pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMFA01050350 9,10 diHOME pmol/ml medium Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LMFA01050350 9,10 diHOME pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LMFA01050350 9,10 diHOME pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LMFA01050350 9,10 diHOME pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMFA01050350 9,10 diHOME pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0014) 9,10 diHOME pmol/ml Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0007) 9,10 diHOME pmol/ml