Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: Cholestanol Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 31.531.8 30 31.8 133 146 138 126 41.5 48.3 46.6 41.2 40.1 45.2 35.4 26.2 28.8 48 51.7 36.4 33.8 37.3 40.7 42.5 35.6 31.2 48 53.7 42.5 34.9 37.5 38.9 38.6 32.3 19.9 31.7 38.2 35.4 15.5 37.6 36.3 47.1 15.8 35.4 28.7 21.7 19.7 18 20.1 15.8 14.2 46.2 22.6 34.9 27.9 21.6 10481 3346 6937 2065 4779 7417 4251 3409 9678 5850 7656 4246 5902 12243 8555 10582 7513 5171 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01010077 Cholestanol - 7.36 - 6.87 6.98 6.43 6.62 5.5 5.76 4.03 5.96 5.28 6.94 5.35 4.99 5.69 6.84 9.2 6.33 9.34 4.95 5.21 5 6.99 - 4.95 4.92 5.65 4.39 5.69 4.78 8.07 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01010077 Cholestanol - 6.56 - 10.1 7.73 8.2 12.4 9.23 7.02 7 9.98 9.27 6.81 7.16 11.3 8.6 6.51 6.8 14.5 14.7 6.9 7.21 8.24 12.2 7.33 10.2 11.8 10.1 6.31 9.5 12.1 17 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01010077 Cholestanol - 72 - 70.3 78.8 66.8 74.4 36.7 70.7 47.7 63.5 58.8 54.9 47.5 71.7 69.7 49.1 75.8 49.1 84.6 53.9 58.1 68 106 - 41.1 67.7 84.8 51.7 48.7 48.6 90.6 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01010077 Cholestanol - 64.2 - 103 87.3 85.2 139 61.6 86.1 82.8 106 103 53.9 63.6 162 105 46.7 56 113 133 75.1 80.4 112 185 72.4 84.9 162 151 74.3 81.3 123 191 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMST01010077 Cholestanol umol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMST01010077 Cholestanol umol/ml of media Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LMST01010077 Cholestanol pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LMST01010077 Cholestanol pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LMST01010077 Cholestanol pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMST01010077 Cholestanol pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0010) LMST01010077 Cholestanol pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0005) LMST01010077 Cholestanol pmol/ml