Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: LPE(20:4) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 6.347.93 9.27 14.7 4.45 3.82 6.19 4.55 5.22 5.93 8.8 8.71 5.47 4.9 7.33 5.41 - 1.21 - 1.67 1.87 3.88 2.67 3.64 - 0.994 - 1.37 1.6 3.19 2.64 4.55 19.1 7.14 1.9 2.05 0.78 2.23 1.56 - 16.5 7.18 1.67 2.25 0.833 2.57 1.61 - 35.5 40.8 90.7 74.7 70.2 72.7 37.3 20.8 16.5 37 50.4 25.7 14.2 37.7 38 9.7 46.4 46.3 44.3 40.5 25.2 17.6 15.5 20.9 18.8 10.7 9.2 239 183 47.5 31.3 50.9 56.5 38.1 28 22 - 20.3 59.4 14.6 20.3 40 11.8 52 26.2 43.7 49 15.7 26209 3403 5592 13766 16282 6132 5944 5396 24543 10369 12156 7757 5725 4718 18794 9525 6953 9650 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(20:4) - 8.25 - 19.5 11.6 15.2 14.3 22.9 13.2 10.4 16.8 14 39.1 44.1 14.4 12.3 60 62.9 60.4 36.1 51.3 50.5 53.4 38.2 21.7 18.4 39.1 41.9 14.9 28.8 24 22.9 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(20:4) - 62 - 181 3.8 7.91 19.5 13.7 3.48 5.68 2.2 6.27 3.67 2.39 5.35 2.6 8.29 8.49 30 7.45 5.65 22.5 66.8 19.1 45.1 93.7 7.74 6.05 99 83.7 56.9 104 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(20:4) - 6.16 - 54.4 4.42 4.89 6.01 5.97 - 18.4 31.4 18.7 70.8 - 63.3 10.1 119 50.6 - 191 110 4.6 64.1 2.03 34.4 4.54 20 11.8 17.3 10.6 11.3 23.4 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(20:4) - 80.7 - 199 131 158 161 153 161 123 179 156 309 392 206 151 431 518 468 326 558 564 726 578 215 153 538 628 175 246 244 257 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(20:4) - 460 - 1697 31.4 70 173 149 32.2 56.5 21.9 72.8 28.2 26.7 65.4 28.1 64.3 56.1 281 52.8 56.8 240 797 199 381 905 83 83.9 986 776 611 1047 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(20:4) - 49.4 - 406 32.1 28.3 35.6 42.5 - 114 204 137 493 - 361 78.7 815 344 - 900 743 30.7 485 11.4 178 20.8 108 83.8 92.4 51.7 52.2 121 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LPE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LPE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LPE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LPE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0005) LPE(20:4) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0014) LPE(20:4) pmol/ml