Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: LPE(22:5) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 -6.08 4.83 8.04 3 2.15 2.8 2.69 - 4.55 4.59 4.78 3.68 2.76 3.32 3.19 0.33 0.66 0.12 0.86 0.81 2.26 1.45 2.53 0.397 0.543 0.146 0.706 0.693 1.86 1.43 3.16 9.61 3.64 0.86 1.06 0.37 1.52 - - 8.3 3.66 0.756 1.17 0.397 1.76 - - 15.7 16.2 34.2 27.7 26.2 26.5 13.7 7.9 6 16.6 22.7 10.8 6.6 14.6 14.4 4.3 16.4 15.7 20.8 20.1 11.3 7.8 6.7 9.3 7.2 4.5 4.4 107 70.7 16.9 2.76 11 7.1 15.9 7.65 3.93 4.77 3.74 13.4 - 3.91 4.7 4.54 4.56 4.33 5.39 7.01 3.94 998 1051 1591 1105 3678 3334 2798 1997 1397 2118 2836 2625 1890 2278 1415 1958 2735 1850 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(22:5) - 4.05 - 8.29 5.34 7.01 6.43 11.6 6.13 4.78 8.6 7.03 18.2 21 6.8 6.19 29.4 31.2 30.5 15.9 26 25.7 27.8 18.4 8.04 8.86 18.7 20.3 7.88 13.4 11.9 9.82 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(22:5) - 28.2 - 80 3.61 6.31 8.17 5.88 3.54 7.53 3.07 6.54 4.15 3.53 4.34 2.41 3.61 3.68 13.9 3.13 2.34 9.26 28.3 7.71 21.7 38.4 5.74 4.41 44.7 32.7 24.6 40.5 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(22:5) - 2.58 - 23 1.67 1.9 2.18 2.31 - 6.42 11 7.26 33.5 - 26 4 59 21.5 - 96.2 53.9 1.43 30.2 0.64 14.6 1.59 8.4 4.39 8.24 3.96 5.37 9.84 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(22:5) - 39.6 - 84.8 60.3 72.9 72.2 77.3 75.2 56.5 91.6 78.3 144 186 97.7 75.8 211 257 237 144 282 286 378 278 79.5 73.5 258 305 92.8 115 121 110 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(22:5) - 209 - 752 29.8 55.8 72.5 64.1 32.8 75 30.5 75.9 31.9 39.4 53.1 26.1 28 24.3 130 22.2 23.5 98.9 337 80.1 183 372 61.6 61.1 446 303 264 407 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(22:5) - 20.7 - 171 12.1 11 12.9 16.4 - 39.9 71.2 53 233 - 148 31.2 404 147 - 454 364 9.55 228 3.58 75.4 7.28 45.2 31.1 44.1 19.3 24.9 50.9 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LPE(22:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LPE(22:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LPE(22:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LPE(22:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0015) LPE(22:5) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0001) LPE(22:5) pmol/ml