Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: LPE(22:6) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 -3.96 4.81 6.83 1.82 2.32 2.29 2 - 2.96 4.57 4.06 2.23 2.98 2.72 2.38 - 0.55 - 0.69 0.72 1.39 1.07 1.93 - 0.451 - 0.568 0.618 1.14 1.05 2.41 8.09 2.98 0.75 - 0.35 1.38 - - 6.99 3 0.66 - 0.374 1.59 - - 19.3 19.2 39.3 36.5 31.7 32.1 17.2 10.2 7.5 21.5 21.6 11.6 7.2 16.8 16.8 5.4 18.3 17.6 28.3 20 12.6 9.4 7.9 10.8 8.1 5.5 5.7 97.8 67.7 18.9 12.5 10.3 32.8 34.2 28 13.4 11 31.6 15.7 11 10.1 17.5 21.2 19.6 14 19.7 18.7 19.6 3486 10366 14229 9312 7078 1514 3240 2889 6247 3117 4399 4058 6760 5298 6146 4523 3899 4135 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) LPE(22:6) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(22:6) - 4.6 - 10.9 6.52 7.63 7.47 11 7.95 5.39 8.76 8 20.7 23.2 6.9 5.82 31.9 34.5 29.9 17.7 27 26.8 24.7 17.7 10.9 11.7 18.5 20.4 8.72 12.3 13.6 9.62 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(22:6) - 31.1 - 80.6 1.95 3.97 8.73 5.83 1.83 3 1.2 3.37 2 1.19 2.41 1.22 4.18 3.88 13.4 3.54 2.63 10.1 26.3 8.23 21.1 43.1 3.48 2.27 43.9 36.1 24.7 42 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(22:6) - 2.63 - 23.3 2.02 2.52 2.53 2.51 - 7.85 11.6 7.41 36.4 - 26.1 4.32 59.8 23.8 - 91.9 54.3 2 28.1 0.82 13.6 1.75 7.23 4.17 7.69 4.52 5.3 9.04 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LPE(22:6) - 45 - 111 73.7 79.3 83.9 73.3 97.5 63.8 93.4 89.1 163 206 99.1 71.3 229 284 232 160 294 299 336 268 108 96.9 255 306 103 105 139 108 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LPE(22:6) - 231 - 758 16.1 35.1 77.5 63.6 16.9 29.9 11.9 39.1 15.4 13.3 29.5 13.2 32.4 25.6 125 25.1 26.4 107 314 85.5 178 417 37.3 31.5 437 335 265 422 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LPE(22:6) - 21.1 - 174 14.7 14.6 15 17.9 - 48.8 75.1 54.1 253 - 149 33.7 409 162 - 434 367 13.4 212 4.59 70.4 8.02 38.9 29.5 41.1 22.1 24.5 46.8 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LPE(22:6) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LPE(22:6) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LPE(22:6) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LPE(22:6) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0008) LPE(22:6) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0007) LPE(22:6) pmol/ml