Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: LPI(18:0)

Legend:graph_icon: View detailed data for replicatesgraph_icon: View time course graphs
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
19.719.628.9 46.3 40.1 31.8 20.5 15.8 9.8 45.6 77.4 68 58.3 80.7 72.4 34 44.3 49.2 43.1 85.1 54.7 41.6 30.6 40 43.4 22.8 20.8 38.5 44.1 9.25 - 5.42 8.5 3.44 5.1 4.41 6.35 4.21 - 2.6 - 6.59 4.86 9.17 - - 7.84 14.2 9363 2080 2669 6520 3622 8826 4052 3005 - 4835 18077 8053 7161 5516 4853 3589 2764 1503
Details Graph
Individual
Expts		Ave Biol. Reps
LM_ID Name 25-OHC*
*
25-OHC
Ctrl
 0 hrs		 25-OHC*
*
25-OHC
Ctrl
 30 min		 25-OHC*
*
25-OHC
Ctrl
 1 hr		 25-OHC*
*
25-OHC
Ctrl
 2 hrs		 25-OHC*
*
25-OHC
Ctrl
 4 hrs		 25-OHC*
*
25-OHC
Ctrl
 8 hrs		 25-OHC*
*
25-OHC
Ctrl
 12 hrs		 25-OHC*
*
25-OHC
Ctrl
 24 hrs		Units
. . . .
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		 LPI(18:0) -
6.85
-
3.44		 3.97
4.94
3.62
9.58		 6.78
3.82
4.78
5.34		 8.16
6.81
3.15
7.53		 10.6
11.3
9.81
5.89		 7.36
5.69
6.17
4.27		 9.66
14.2
4.37
4.54		 14.9
12
10.9
7.53		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100427)		 LPI(18:0) -
3.51
-
6.48		 1.89
2.63
3.56
1.77		 1.6
2.09
1.24
2.81		 1.65
1.36
2.95
1.67		 2.8
2.06
5.44
3.17		 3.12
5.83
10.6
2.16		 7.32
9.12
3.92
1.7		 22.8
16.8
10.8
10.5		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100624)		 LPI(18:0) -
1.19
-
2.33		 2.74
2.86
2.18
1.52		 -
4.53
5.46
4.16		 8.42
-
6.37
2.76		 7.74
16.1
-
13.6		 9.95
1.78
9.12
2.4		 7.7
2.62
4.7
2.53		 5.35
5.48
5.13
4.21		 pmol/ug DNA
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)		 LPI(18:0) -
67
-
35.2		 44.8
51.3
40.7
63.9		 83.2
45.2
50.9
59.5		 64.5
60.5
45.3
92.2		 76.1
93
76.1
53.3		 80.1
63.5
83.9
64.6		 95.5
118
60.1
68.1		 175
103
110
84.5		 pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100427)		 LPI(18:0) -
26
-
60.9		 15.6
23.3
31.6
19.3		 14.8
20.8
12.3
32.6		 12.7
15.2
36.1
18.1		 21.7
13.6
50.9
22.5		 31.3
62.3
126
22.4		 61.7
88.2
42
23.6		 227
156
116
105		 pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100624)		 LPI(18:0) -
9.53
-
17.4		 19.9
16.5
12.9
10.8		 -
28.2
35.5
30.4		 58.6
-
36.3
21.6		 53
110
-
64.2		 67.2
11.9
68.9
13.4		 39.8
12
25.3
17.9		 28.6
26.7
23.7
21.8		 pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCG120120)		 LPI(18:0) pmol/10E6 cells
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCG120131)		 LPI(18:0) pmol/10E6 cells
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCG120212)		 LPI(18:0) pmol/10E6 cells
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCG120308)		 LPI(18:0) pmol/10E6 cells
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(NASH0010)		 LPI(18:0) pmol/mg
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(NASH0008)		 LPI(18:0) pmol/ml