Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: Oleic acid Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 254104 88.3 185 148 196 342 129 84.1 114 87.1 122 68.6 59.1 46.5 176 223 156 112 126 133 141 162 244 199 192 173 176 160 171 169 162 149 141 167 183 160 169 146 36.5 44 37.2 54.3 48.6 45.1 49.3 47.6 71.3 60.7 60.9 43 47.6 41.5 54.3 45.2 55.6 50.2 37.3 45.1 40.8 41.5 68.9 64.8 49.7 76.3 45.5 74.4 40.2 33.2 45.5 47.5 40.9 57 43.2 44.2 49.3 42.7 53.9 56.5 50.1 48 45.9 55.8 69.8 55.8 52.6 47.4 59.9 39.6 57.5 45.7 59.5 45.9 52 59.3 41.8 45.8 49.7 34.8 35.1 34.1 47.3 52.8 36.1 46 43.6 38.2 37.3 39.3 48.9 47.6 531 504 583 272 324 381 287 207 96.1 89.1 156 209 178 418 195 150 109 87.7 85.2 127 169 142 111 124 81.1 98.6 94.7 44.3 18.6 76.8 17.4 17.3 24.4 28.5 35.4 247 365 186 296 356 382 200 229 293 749 706 805 399 659 757 1000 1047 907 429 813 566 466 725 549 745 471 303 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070804) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070612) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070804) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070814) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070817) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080227) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080520) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080520) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080702) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080702) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG080702) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090924) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090924) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090928) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090928) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090928) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG090928) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA01030002 Oleic acid - 58.6 - 37 67 64.6 46.1 59.1 49.3 48 39.7 51.5 60.7 72.3 26.2 35.3 71.6 54.1 44.1 47.7 58.6 51.4 40 26.6 69.4 64.8 36.5 36.5 44.2 75.4 48.1 42 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA01030002 Oleic acid - 73.3 - 37 61.7 98.9 49.1 43.8 68.4 65.3 51.7 43.4 63.2 46.3 31.8 42.3 68.2 86.2 45.9 61 50.9 55.9 46.5 50.1 66.4 68.2 59.2 61.5 98 62.6 49.1 52.6 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMFA01030002 Oleic acid - 106 - 93.6 164 188 144 90.2 115 137 126 151 150 111 132 119 153 142 152 162 139 129 111 174 199 176 133 106 232 224 194 180 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMFA01030002 Oleic acid - 574 - 379 756 671 518 394 605 568 423 574 480 642 376 432 514 446 342 432 637 573 544 403 686 537 501 548 521 645 489 471 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMFA01030002 Oleic acid - 544 - 348 510 875 435 478 633 650 513 504 486 517 388 457 529 569 429 432 511 597 555 521 560 659 635 853 977 580 526 529 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMFA01030002 Oleic acid - 848 - 698 1188 1085 853 641 843 855 817 1100 1045 731 751 926 1049 965 681 763 939 864 839 975 1026 806 716 752 1240 1092 896 932 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMFA01030002 Oleic acid pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070831) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070927) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070830) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070924) LMFA01030002 Oleic acid pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070919) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD070816) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070316) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070316) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSG070316) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD070716) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD070816) LMFA01030002 Oleic acid pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) LMFA01030002 Oleic acid pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) LMFA01030002 Oleic acid pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) LMFA01030002 Oleic acid pmol/10E6 cells