Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PC(28:0) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 2.221.76 2.22 2.3 0.96 0.85 1.06 1.02 1.83 1.31 2.11 1.37 1.18 1.09 1.26 1.22 - - 0.55 1.67 0.57 0.62 0.91 - - - 0.693 1.37 0.485 0.51 0.902 - 2.34 2.72 5.64 3.75 0.52 4.07 - 3.84 2.02 2.73 4.95 4.11 0.556 4.68 - 3.46 0.5 0.425 0.5 0.465 0.45 0.365 0.705 1.05 1.05 3.2 2.9 1.65 1.8 3.3 1.6 2.45 2.5 2.35 2.25 2.2 1.6 2.6 1.4 3.35 3 2.05 2.8 2.6 2.2 2.3 1.05 1.38 0.467 0.38 3.38 1.86 1.36 2.68 2.03 1.39 292 0.6 0.44 0.49 - 0.48 0.49 0.45 0.86 1.98 1.72 1.66 2.27 2.4 2.41 1.1 1.48 2.8 2.4 2.27 4.81 2.52 2.37 1.51 1.81 1.24 2.57 1.98 3.14 1.36 1.43 1.96 1.94 8.38 10 2.4 4.79 3.36 1.24 1.4 3.09 299 301 0.52 - - - - - 1.03 - 2.03 - 0.05 0.09 0.18 18.3 0.44 0.18 0.5 0.46 0.53 0.57 0.48 0.53 0.84 0.86 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(28:0) - 7.55 - 4.09 4.36 4 2.41 3.49 4.7 2.97 4.42 3.09 9.76 7.59 3.72 4.08 6.47 4.88 5.91 4.97 6.58 5.64 4.72 4.11 8.82 12.4 4.78 4.47 9.2 7.83 6.9 3.8 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(28:0) - 4.19 - 5.58 3.7 4.9 5.32 2.8 4.26 4.41 2.82 3.94 4.67 3.41 4.93 3.17 5.62 6.54 4.95 5.59 4.35 3.11 4.36 4 4.51 3.51 4.87 2.78 5.4 3.75 4.62 3.36 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(28:0) - 3.15 - 3.57 2.65 4.48 3.98 3.57 - 4.11 4.33 4.23 4.08 - 5.3 5.67 3.33 3.53 - 6.16 3.59 5.69 3.66 7.42 7.86 8.23 10.9 6.4 7.98 4.6 10.2 9.34 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(28:0) - 73.9 - 41.8 49.3 41.6 27.1 23.3 57.6 35.1 47.1 34.4 77.2 67.4 53.4 50 46.4 40.2 45.8 45 71.6 62.9 64.2 62.2 87.2 103 65.8 67.1 108 67 70.1 42.7 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(28:0) - 31.1 - 52.5 30.6 43.4 47.2 30.5 39.4 43.9 28 45.7 35.9 38.1 60.3 34.3 43.6 43.2 46.3 39.6 43.7 33.2 52.1 41.5 38 33.9 52.2 38.5 53.8 34.8 49.6 33.8 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(28:0) - 25.2 - 26.6 19.3 25.9 23.6 25.4 - 25.6 28.2 30.9 28.4 - 30.2 44.3 22.8 24.1 - 29.1 24.2 38 27.7 41.5 40.6 37.7 58.8 45.3 42.7 22.4 47.1 48.3 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH050817) PC(28:0) Normalized Int Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060201) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060208) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060215) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ060718) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG070306) PC(28:0) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070829) PC(28:0) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCHSUB000) PC(28:0) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080304) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080805) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB100) PC(28:0) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB200) PC(28:0) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081021) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081028) PC(28:0) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081209) PC(28:0) pmol/ug DNA