Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PC(30:0) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 78.658.650.9 57.8 41.3 39.5 31.9 21.1 12.9 122 79.9 68.3 59 53.9 62.1 95.6 38.2 35 125 106 85.4 62.5 62.4 74.7 58 48.5 10.2 209 184 40.4 1.6 1.7 1.95 1.68 1.87 1.81 2.05 - - 11.1 - - 9.28 - 8.75 - - - 5.86 29 - 9.5 - - 13.5 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(30:0) - 4.03 - 12.7 2.98 3.11 2.52 4.39 4.43 2.57 2.78 4.06 17.7 22.7 5.58 4.11 11.3 8.35 10.1 10.3 9 9.73 8.1 7.02 5.37 8.58 7.94 7.56 3 5.97 7.39 2.9 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(30:0) - 36 - 43.7 24.6 35.9 48.9 24.9 28.4 36.5 22.6 36.8 35.7 25.1 42 24.8 110 145 34.4 45.1 21.9 23.1 24.8 27 20.6 21.6 26.2 19.2 21.2 24.7 19.8 24.4 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(30:0) - 21 - 25 16.9 25.2 27.7 20.2 - 24.4 23.3 19.6 14.4 - 18.5 18.9 10.1 13.8 - 24.9 9.91 33.8 12.7 53.4 38.5 47.3 50.3 48.6 29.1 27.1 44.7 31.4 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(30:0) - 39.4 - 130 33.7 32.3 28.3 29.3 54.3 30.4 29.6 45.2 140 201 80.2 50.3 81.2 68.8 78.4 92.9 97.9 109 110 106 53.1 71.2 109 113 35.3 51.1 75.1 32.6 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(30:0) - 267 - 410 203 318 434 271 263 364 224 427 275 280 513 269 850 960 322 320 220 247 297 280 174 208 281 266 211 229 212 245 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(30:0) - 168 - 187 123 145 164 144 - 152 151 143 100 - 105 148 68.9 94.2 - 117 66.9 226 96.3 299 199 216 270 344 155 132 207 163 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) PC(30:0) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) PC(30:0) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) PC(30:0) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) PC(30:0) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH050817) PC(30:0) Normalized Int Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0015) PC(30:0) pmol/mg