Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PC(38:5) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 23.933.7 23.1 38.9 9.79 9.51 20.9 15.7 19.6 25.2 21.9 23.1 12 12.2 24.8 18.7 18 12.6 7.26 14.4 11.7 15.9 22 79.6 21.5 10.4 9.08 11.8 9.95 13 21.7 99.5 4.3 5.75 13.3 - 2.58 - - - 3.71 5.79 11.7 - 2.74 - - - 148 220 216 228 232 206 143 113 63.6 169 240 195 164 201 174 140 106 124 192 309 154 138 122 138 131 67.3 61.9 267 177 60.6 0.755 0.74 0.605 0.555 0.52 0.435 0.52 1442 1603 1568 34.6 1424 757 514 1463 475 350 375 1113 692 437 608 505 569 427 502 411 539 1306 229157 286294 120804 207386 291301 50014 145456 190715 130649 208423 177602 153554 99914 194856 173802 111625 113076 194760 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PC(38:5) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(38:5) - 24 - 10.5 17.7 21.2 20.4 40.8 19.1 12.1 28.3 23.2 38.2 92.6 23.6 20.6 33.3 19.9 33.6 35.6 29.5 25.4 33.4 24.5 22.8 26.7 27.3 25.1 12.6 19.3 34.9 18.1 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(38:5) - 139 - 146 104 145 182 102 101 131 91.2 131 125 87.1 131 88 110 140 115 152 39.6 35.5 48.7 61.2 44.7 34.3 42.7 28.8 44.2 36.8 36.1 43.4 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(38:5) - 99.4 - 77 63.3 93.1 101 107 - 20.4 30.3 47.9 84.1 - 133 84.7 76.6 82.6 - 156 63.6 26.7 85.5 50.5 33 30 53.5 29.6 36.6 18.7 40.4 116 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PC(38:5) - 235 - 107 200 221 230 272 235 143 301 258 302 822 339 252 239 164 260 323 321 283 454 370 226 222 376 376 149 165 354 203 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PC(38:5) - 1031 - 1372 863 1280 1613 1108 931 1302 906 1516 963 973 1601 952 855 924 1079 1076 397 379 582 635 377 332 458 399 440 341 387 436 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PC(38:5) - 796 - 574 460 538 600 764 - 127 197 350 585 - 760 662 524 563 - 739 429 178 647 282 170 138 288 210 196 91 187 598 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) PC(38:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) PC(38:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) PC(38:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) PC(38:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH050817) PC(38:5) Normalized Int Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070122) PC(38:5) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070123) PC(38:5) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070829) PC(38:5) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCHSUB000) PC(38:5) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB100) PC(38:5) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB200) PC(38:5) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) PC(38:5) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0001) PC(38:5) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0014) PC(38:5) pmol/ml