Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PE(40:4) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 5.535.71 5.86 11.3 4.74 3.77 5.24 4.52 4.55 4.26 5.57 6.71 5.82 4.85 6.21 5.37 3.45 4.31 2.1 5.16 5.99 7.13 5.09 9 4.12 3.55 2.63 4.23 5.11 5.86 5.03 11.2 7.6 7.46 3.47 2.61 3.57 4.5 4.44 4.95 6.56 7.5 3.04 2.87 3.79 5.19 4.59 4.46 71.5 89 74.4 79.6 86.1 67.2 56.3 52.4 24.6 222 239 211 191 173 174 120 78.6 93.3 206 302 173 165 159 162 113 69.9 72.9 90 51.1 26.8 8.85 8.55 20.9 11.4 7.95 9.55 19.9 7.95 7.05 9.75 8.95 4.45 9 7.9 11.7 4.5 10.6 10 7.4 8.35 8.3 7.2 9.7 3.75 8.35 4.07 2.91 6.89 3.16 2.9 7.23 4.19 3.61 652 2.08 1.69 1.05 0.63 0.92 1.1 0.82 1.03 10.1 8.82 5.89 6.22 4.43 2.9 3.59 2.98 7 6.12 4.12 4.74 4.21 3.44 3.3 2.68 5.82 6.22 5.77 4.49 4.06 5.08 2.96 2.89 8.86 4.78 18.1 18.2 14.2 31.4 15.1 6.68 657 653 26.8 39.5 32.7 23.2 28.3 20.4 36 33.8 28.3 21.4 34.8 17.5 18.3 14.1 16.6 11.4 58.8 47.3 48.5 48 44.4 46.6 62.3 76.3 18.5 75.9 50.1 63.6 158 49.7 66.5 168 187 144 124 172 125 57.3 44.4 122 209 91.8 223 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PE(40:4) - 3.44 - 9.5 4.43 4.42 4.34 6.96 5.14 3.75 6.27 5.11 15.4 6.73 5 5.21 9.51 8.1 9.97 6.24 6.33 6.08 5.71 4.58 6.28 8.1 5.28 5.31 7.71 7.28 9.42 5.46 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PE(40:4) - 23.7 - 31.2 12.9 20.3 27.5 11.7 10.9 15.8 11.2 20.8 11.1 8.18 17.7 9.35 10.5 11.8 13.9 16.4 7.71 7.76 9.46 8.33 9.17 9.03 8.88 4.67 16.6 13.9 9.77 11 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PE(40:4) - 8.27 - 18 5.38 7.48 8.2 7.73 - 7.15 7.93 7.58 10.4 - 14.6 7.44 13.2 10.8 - 22.1 13.9 18.1 11.4 7.94 9.77 7.8 8.24 7.86 6.94 7.27 10.6 10.2 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PE(40:4) - 33.7 - 97.2 50 45.9 48.8 46.4 63 44.4 66.8 56.9 122 59.8 71.8 63.8 68.2 66.7 77.3 56.5 68.9 67.8 77.7 69.3 62.1 67.2 72.6 79.7 90.8 62.3 95.7 61.3 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PE(40:4) - 175 - 293 107 179 244 127 101 157 111 242 85.6 91.4 216 101 81 77.7 130 117 77.5 82.9 113 86.5 77.3 87.3 95.2 64.7 165 129 105 110 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PE(40:4) - 66.3 - 135 39.1 43.2 48.6 55 - 44.5 51.6 55.4 72.5 - 83.4 58.1 90.4 73.7 - 104 93.6 121 85.8 44.4 50.4 35.7 44.3 55.7 37.1 35.5 48.9 52.6 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) PE(40:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) PE(40:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) PE(40:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) PE(40:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060201) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060208) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060215) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ060718) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG070312) PE(40:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG061213) PE(40:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070829) PE(40:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070918) PE(40:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCHSUB000) PE(40:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080304) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080805) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB100) PE(40:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB200) PE(40:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081021) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081028) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081209) PE(40:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) PE(40:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0017) PE(40:4) pmol/mg