Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PI(36:2) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 7.618.58 5.77 7.21 3.49 2.64 4.67 3.3 6.26 6.41 5.48 4.29 4.28 3.39 5.54 3.93 5 8.5 2.3 3.86 4.67 5.13 5.89 6.82 5.97 7.01 2.87 3.17 3.99 4.21 5.82 8.52 6.31 5.07 4.59 4.33 0.39 4.93 3.05 4.88 5.45 5.1 4.03 4.76 0.417 5.68 3.16 4.4 126 110 106 139 127 115 87.1 62.4 33.5 175 197 177 145 162 159 107 90 111 157 210 126 92.2 82.3 94.4 97.2 55.1 39.9 90.5 85 48.3 3.15 4.3 16.7 13 6.3 11.5 30.1 16.6 22.9 20.4 19.8 20.5 20.7 17.3 29.3 20.7 16.5 16.7 8.1 18.5 17.2 17.9 21.5 10.1 9.54 6.11 5.76 35.7 21.2 17.4 21.2 18.1 13.4 107 0.62 0.23 0.24 0.21 0.34 0.42 0.16 0.9 14.4 17.2 16.3 17.5 16.3 14.4 13.2 12.2 24.4 18.9 17.1 16.8 19.8 15.7 13.6 11.2 20.3 14.9 14.2 13.5 13 13.6 10.8 11.2 12.2 9.59 8.82 6.29 6.81 6.71 9.02 3.95 116 117 1.92 1.91 3.12 1.82 3.27 2.9 2.66 3.37 8.13 3.76 3.29 3.05 4.12 4.03 3.11 2.86 12.3 11.5 9.91 9.95 8.88 11.8 16.2 14 9.63 13 7.04 39.3 24.6 18.8 14.9 21.6 65.6 15.6 31.4 45.8 21.9 29 12.2 17.4 53.7 30 23.2 4106 5584 3695 3380 9409 7888 9702 4963 7085 6013 7035 4494 6385 5152 6676 7258 3565 6916 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PI(36:2) - 5.39 - 9.04 5.05 9.46 6.61 8.62 9.17 7.14 8.97 5.49 11.8 7.04 7.41 10.5 9 10.1 8.94 4.91 7.82 7.16 5.91 4.23 22.9 28.9 4.64 5.44 18.6 35.2 18.9 15.4 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PI(36:2) - 9.59 - 6.84 11.8 18.3 14.7 4.67 15.3 18.3 6.35 14.8 18.7 13.3 19.5 8.55 17 21.3 19.7 24.6 12.8 11.7 17.3 18.9 19.7 13.6 11.7 9.35 35 37.9 20.7 19.1 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PI(36:2) - 15.5 - 18.2 20.4 27 22 17.7 - 26.1 21 34.8 22.5 - 13.8 23.5 12.7 27.6 - 20.7 14.3 31.7 16.3 59 44.4 71.9 51.4 40.8 54.3 47.7 25.5 36.5 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PI(36:2) - 52.7 - 92.5 57 98.3 74.3 57.5 112 84.4 95.6 61.2 93 62.5 106 129 64.6 83.3 69.3 44.5 85.1 79.9 80.4 64 227 240 63.8 81.6 219 301 192 172 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PI(36:2) - 71.1 - 64.3 97.1 162 130 50.9 141 182 63.1 172 143 148 238 92.5 132 141 184 175 129 125 206 196 166 131 125 130 348 351 222 192 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PI(36:2) - 124 - 136 148 156 130 126 - 162 137 254 156 - 78.6 183 87.1 188 - 97.9 96.6 211 123 330 229 329 277 289 290 233 118 189 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) PI(36:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) PI(36:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) PI(36:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) PI(36:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060201) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060208) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060215) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ060718) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070122) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070123) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG070306) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG061213) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070829) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070918) PI(36:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCHSUB000) PI(36:2) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080304) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080805) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB100) PI(36:2) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB200) PI(36:2) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081021) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081028) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081209) PI(36:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) PI(36:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0010) PI(36:2) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0016) PI(36:2) pmol/ml