Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: PI(36:4) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 2.772.66 1.73 2.22 1.12 0.96 1.49 0.82 2.28 1.99 1.64 1.32 1.37 1.23 1.77 0.979 5.22 2.83 0.6 0.41 1.93 2.18 1.46 2.48 6.24 2.34 0.752 0.338 1.65 1.79 1.45 3.1 1.62 1.66 1.85 3.3 0.69 3.08 2.72 - 1.4 1.67 1.62 3.62 0.733 3.55 2.81 - 28.6 24 25.5 31 28.8 25.6 19.7 13.1 6.7 38.2 39.6 31.6 25.7 32.5 34.3 22.3 16.6 15.3 45.5 51 32.9 23.8 21.2 24.8 20.3 11.9 7.8 33.3 29.3 12.4 1.15 1.45 6.05 4.6 1.75 3.3 6.7 2.4 4.6 4.45 3.85 3.85 3.85 2.6 3.85 2.4 4.8 4.95 1.95 4.9 3.85 3.45 3.9 1.15 3.43 1.49 0.807 6.5 2.81 1.79 4.28 2.53 1.55 15.1 0.09 0.03 0.06 0.12 0.05 0.08 - - 2.37 2.3 2.2 2.33 2.19 1.56 1.16 0.88 3 2.73 2.61 2.47 2.56 1.78 1.26 0.8 3.24 2.25 2.43 2.11 2.04 2.53 1.31 0.86 10.5 7.05 3.85 3.31 3.35 2.05 2.22 1.01 15.8 16 2.53 2.04 5.09 2.36 3.23 2.65 3.04 4.08 4.26 1.97 1.68 1.7 2.29 2.27 2.09 1.61 6.8 6.33 5.39 5.91 5.28 6.68 9.21 7.94 2.69 18.1 183 31 24.4 70.3 93.3 19.8 19.5 45.9 66.2 36.7 55.4 45.8 26.5 21.3 32.9 20.7 26.5 2024 2535 1975 1998 4213 2958 1245 2234 2998 2634 1884 2263 1133 2652 1590 3360 1715 3532 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH090825) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PI(36:4) - 1.6 - 2.83 1.1 2.36 1.63 2.49 1.87 1.56 2.15 1.47 2.29 1.69 1.84 2.42 2.05 2.25 2.58 1.48 1.8 1.62 2.09 1.25 4.33 4.73 1.65 1.47 2.44 5.13 6.5 3.57 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PI(36:4) - 2.09 - 2.35 2.31 3.83 3.92 1.44 3.05 3.93 1.75 3.66 3.41 2.75 5.65 1.98 3.52 4.44 5.72 6.32 2.7 2.42 5.68 5.19 4.25 2.44 4.43 2.34 6.91 6.46 6.62 4.29 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PI(36:4) - 2.74 - 4.4 3.07 4.5 4.37 3.89 - 5.84 4.7 7.48 4.27 - 3.53 5.14 2.51 5.13 - 4.85 3.05 6.07 4.67 13.4 8.83 13.3 16.1 9.69 13.9 11 8.49 8.12 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) PI(36:4) - 15.7 - 29 12.4 24.5 18.3 16.6 22.9 18.5 22.9 16.4 18.1 15 26.4 29.6 14.7 18.5 20 13.4 19.6 18.1 28.4 18.9 42.8 39.2 22.7 22.1 28.8 43.9 66 40.1 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) PI(36:4) - 15.5 - 22.1 19.1 33.9 34.8 15.7 28.2 39.1 17.4 42.5 26.2 30.7 69.1 21.4 27.3 29.3 53.5 44.8 27.1 25.9 67.8 53.9 35.8 23.6 47.5 32.4 68.8 59.9 71 43.1 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) PI(36:4) - 22 - 32.8 22.3 26 25.9 27.7 - 36.3 30.6 54.6 29.7 - 20.1 40.2 17.2 35 - 22.9 20.6 40.5 35.3 74.8 45.6 60.8 86.7 68.7 74.2 53.5 39.3 42 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) PI(36:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) PI(36:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) PI(36:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) PI(36:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060201) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060208) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH060215) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ060718) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070122) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070123) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG070312) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG061213) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ070619) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070829) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSH070918) PI(36:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCHSUB000) PI(36:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080304) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080805) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB100) PI(36:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCISUB200) PI(36:4) pmol/mg protein Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081021) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081028) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCH081209) PI(36:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) PI(36:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0017) PI(36:4) pmol/mg Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0007) PI(36:4) pmol/ml