Lipidomics Studies on Bone Marrow-derived Macrophages Treated with ATP / Kdo2-Lipid A
Eicosanoids [media]
|
Details | Graph | LM_ID | Name | Kdo+ATP Kdo ATP 15 min |
Kdo+ATP Kdo ATP 30 min |
Kdo+ATP Kdo ATP 1 hr |
Kdo+ATP Kdo ATP 2 hrs |
Kdo+ATP Kdo ATP 4 hrs |
Kdo+ATP Kdo ATP 8 hrs |
Kdo+ATP Kdo ATP 20 hrs |
---|---|---|---|---|---|---|---|---|---|---|
LMFA04000027 | 10-HDoHE | 1.33
1
0.833
| 1.08
1.08
0.917
| 1.5
1.1
1.1
| 1.9
1.1
1.3
| 2.44
1.33
1.33
| 1.73
1
0.909
| 1.62
0.615
0.692
| ||
LMFA03050008 | 11,12-diHETrE | 0.9
0.767
0.833
| 1.13
0.792
0.792
| 0.955
0.955
0.818
| 1.08
0.833
0.667
| 1.53
0.947
1.05
| 2
1.1
0.8
| 2.59
0.941
0.529
| ||
LMFA03010060 | 11beta-PGE2 | 2.18
0.545
0.675
| 3.92
0.525
0.542
| 4.52
0.586
0.431
| 10.6
1.38
0.969
| 11.9
1.31
6.93
| 22.8
3.36
14.9
| 41.3
3.73
25.6
| ||
LMFA04000028 | 11-HDoHE | 0.963
0.778
0.815
| 1.05
0.909
1.14
| 1.74
1.16
1.16
| 1.45
1
1.05
| 1.67
1.05
1
| 1.39
0.826
0.87
| 1.52
0.593
0.741
| ||
LMFA03060085 | 11-HETE | 2.96
0.593
0.577
| 7.66
0.946
0.838
| 5.83
0.925
0.866
| 6.48
0.887
0.745
| 10.9
1.35
5.88
| 5.39
1.01
3.48
| 2.72
0.357
1.5
| ||
LMFA03020022 | 11t LTE4 | 7
1.5
1.5
| 9
1
3.33
| 9.67
1.33
6.67
| 6.5
0.75
4.75
| 9.67
1
6.33
| 6.75
0.75
5.25
| 7.5
1
4
| ||
LMFA01050351 | 12,13 diHOME | 1.38
1.62
1.08
| 1.43
1.07
1.21
| 1.33
0.8
1.2
| 1.15
0.9
1
| 1.13
1
0.938
| 0.905
0.667
0.714
| 1.58
0.833
1
| ||
LMFA03020015 | 12-epi-LTB4 | 2.4
1
1.2
| 4.4
1
2.2
| 3.4
1.2
2.8
| 4.4
1
3
| 4.2
1.2
2.6
| 4.5
1
3.25
| 4
1.25
1.5
| ||
LMFA03060088 | 12-HETE | 1.06
0.85
0.883
| 1.1
0.881
0.976
| 1.26
0.954
1.07
| 1.3
0.831
0.792
| 1.54
0.774
0.887
| 2.27
0.978
0.948
| 1.96
0.359
1.05
| ||
LMFA03070008 | 12S-HEPE | 1.22
1
1
| 0.917
1
1.13
| 1.5
1
1.21
| 1.34
0.897
0.793
| 2
1
1.18
| 2.47
1
1.29
| 3.48
0.333
1.14
| ||
LMFA03050002 | 12S-HHTrE | 1.89
0.964
0.855
| 2.22
0.753
0.882
| 2.42
0.973
0.959
| 2.32
0.819
0.685
| 4.23
0.75
1.74
| 4.6
0.773
1.91
| 23
0.535
2.79
| ||
LMFA03010033 | 13,14-dihydro-15-keto-PGA2 | -
-
-
| 4.5
-
-
| 1.67
0.833
-
| 7.29
-
-
| -
-
-
| -
-
-
| -
-
-
| ||
LMFA03010022 | 13,14-dihydro-15-keto-PGD2 | 3.51
1.28
2.59
| 1.56
0.956
1.56
| 1.95
0.986
1.07
| 2.07
0.776
1.22
| 3.29
0.838
1.73
| 2.62
0.918
1.59
| 3.73
1.03
1.86
| ||
LMFA04000029 | 13-HDoHE | 1.36
0.756
0.822
| 1.18
0.977
0.932
| 1.62
1.16
1.27
| 1.71
1
1.02
| 3.42
1.28
1.64
| 3.75
1.42
1.86
| 5.23
1.11
1.84
| ||
LMFA01050349 | 13-HODE | 1.2
0.993
0.993
| 1.64
1.38
1.46
| 1.35
0.886
0.829
| 1.04
0.729
1.17
| 2.77
1.14
1.93
| 2.8
1.3
1.9
| 2.56
0.98
1.58
| ||
LMFA02000051 | 13-HOTrE | 3.3
2.3
1.7
| 0.727
0.909
0.727
| 0.792
0.875
0.583
| 2
1.07
1.36
| 2.24
1.65
1.12
| 1.03
1.27
0.667
| 2.22
1.5
1.89
| ||
LMFA02000016 | 13-oxoODE | 1.53
1.74
1.21
| 8.78
0.833
0.889
| 2
1.08
1.67
| 0.923
1
1.04
| 1.58
0.542
0.917
| 1
0.76
0.68
| 1.82
1.36
1.82
| ||
LMFA01050145 | 13(S)-HOTrE(gamma) | 1.15
0.986
1.03
| 0.974
0.833
0.897
| 1.32
0.909
0.974
| 1.43
0.987
0.924
| 1.95
0.987
1.24
| 2.67
1.04
1.22
| 5.59
0.839
1.61
| ||
LMFA03050010 | 14,15-diHETrE | 1.29
0.971
1
| 1
0.85
0.775
| 1.32
1.03
1
| 1.32
0.974
0.947
| 1.42
1.06
1.06
| 1.6
1.09
1.09
| 1.92
1
1.19
| ||
LMFA03080005 | 14,15-EET | 3.16
1
1.22
| 3.24
0.976
1.29
| 4.07
1.02
1.51
| 5.1
1.21
1.67
| 9.67
1.28
3.19
| 5.94
1.28
2.69
| 3.87
0.5
1.57
| ||
LMFA04000030 | 14-HDoHE | 1.08
1.02
0.856
| 1.01
0.879
0.989
| 1.64
1.11
1.02
| 1.63
1.14
0.884
| 1.82
1.26
1.07
| 2.15
1.6
1.05
| 2.22
0.97
1.15
| ||
LMFA03010051 | 15-deoxy-delta-12,14-PGD2 | 1.84
1.06
1.22
| 1.57
1.09
1.14
| 1.58
1.1
1
| 1.7
1.06
0.919
| 2.8
1.3
1.31
| 2.72
1.1
1.8
| 9.19
1.46
4.9
| ||
LMFA03010021 | 15-deoxy-delta-12,14-PGJ2 | 1.91
0.455
1.18
| 3.25
0.75
0.833
| 1.45
0.955
0.773
| 2.69
1.08
1.08
| 4.33
1.13
1.47
| 6.93
1.36
3.36
| 13.4
1
6.4
| ||
LMFA03070032 | 15-HEPE | 1.06
0.903
1.03
| 1.06
0.788
0.879
| 1.36
0.939
1.06
| 1.32
0.865
0.811
| 2.04
1.04
1.14
| 3.46
1.08
1.21
| 1.98
0.492
0.407
| ||
LMFA03060087 | 15-HETE | 3
1.04
1.22
| 2.77
0.774
1
| 4.27
1.04
1.38
| 4.46
1
1.54
| 8.68
1.24
2.76
| 7
1.4
3.2
| 3.41
0.432
1.38
| ||
LMFA03050007 | 15-HETrE | 1.44
0.905
1.07
| 1.37
1.02
1.07
| 1.91
1.13
1.26
| 2.04
1.04
1.46
| 3.57
1.17
1.76
| 3.28
1.33
1.62
| 3.49
0.876
1.6
| ||
LMFA04000031 | 16-HDoHE | 1.3
0.845
0.901
| 1.1
1.07
1.01
| 1.42
1.1
1.13
| 1.35
1.05
0.97
| 1.69
1.13
1.17
| 1.76
1.19
1.24
| 1.88
1.1
1.08
| ||
LMFA03060069 | 16R-HETE | 0.9
0.7
1
| 0.588
1.06
1.21
| 1.54
0.875
1.13
| 1.45
0.895
0.895
| 2.42
1.17
1.71
| 1.88
0.76
1.2
| 1.03
1.59
1.12
| ||
LMFA04000032 | 17-HDoHE | 1.29
0.867
1.03
| 1.16
0.988
0.902
| 1.56
1.07
1.13
| 1.61
1.06
0.987
| 2.06
1.1
1.17
| 2.29
1.33
1.19
| 2.43
0.9
1.1
| ||
LMFA03060091 | 17-HETE | 1.52
1.14
1.24
| 0.905
1.05
2.24
| 1.17
1.03
1.07
| 1.36
0.714
1.64
| 1.9
0.952
1.48
| 1.96
1.22
1.04
| 0.92
0.38
0.44
| ||
LMFA03070033 | 18-HEPE | 1.7
1.15
1.2
| 0.929
1.64
2.14
| 1.68
0.789
0.947
| 1.71
1.14
1.14
| 2.38
1.15
2.31
| 2.36
1.57
2.36
| 2.35
0.55
1.6
| ||
LMFA03060092 | 18-HETE | 1.5
0.697
0.885
| 0.572
0.753
1.02
| 1.14
0.702
0.951
| 1.63
1.06
1.55
| 1.23
0.662
0.91
| 1.81
1.44
1.17
| 1.41
0.507
0.793
| ||
LMFA04000043 | 19,20 DiHDPA | 1.31
0.964
0.932
| 0.862
0.96
0.931
| 1.3
0.952
1.1
| 1.46
1.07
0.961
| 1.45
1.05
1.07
| 1.45
1.06
1.06
| 1.07
0.827
0.886
| ||
LMFA03060074 | 19-HETE | 1.54
1.26
1.44
| 1.39
1.09
1.84
| 1.51
1.09
1.57
| 1.64
1.15
1.33
| 1.56
0.921
1.37
| 1.82
0.867
1.45
| 1.43
0.9
1.1
| ||
LMFA04000033 | 20-HDoHE | 1.39
0.903
0.917
| 1.18
1.1
1.06
| 1.72
1.22
1.33
| 1.51
0.908
1.05
| 2.23
1.19
1.41
| 2.44
1.34
1.47
| 2.29
1.09
1.2
| ||
LMFA03010011 | 2,3-dinor-11b-PGF2alpha | 4
0.6
2.8
| 2.67
1
2.11
| 3.29
1.29
4.14
| 2.86
2
3.86
| 1.75
0.875
1.44
| 1.33
0.611
1.5
| 1.52
0.704
1.48
| ||
LMFA04000024 | 4-HDoHE | 1.23
0.871
1.03
| 1.26
0.8
1.2
| 2.24
1
1.48
| 3.09
0.939
1.7
| 4.15
1.04
1.92
| 2.87
1.13
1.48
| 1.66
0.448
0.69
| ||
LMFA03060010 | 5,15-diHETE | 1.19
1.13
1.06
| 1.25
1
1
| 1.77
1.15
1.31
| 1.57
1.36
1.36
| 1.29
1.12
1.18
| 1.33
1
1
| 1.33
1
1
| ||
LMFA03070027 | 5-HEPE | 1.5
1
1.25
| 3
1
1.75
| 3.67
1.67
2
| 3
0.75
1.25
| 5.75
1
1.75
| 7.67
1.33
1.67
| 0.303
0.171
0.066
| ||
LMFA03060084 | 5-HETE | 2.42
1.06
1.22
| 3.35
0.95
1.6
| 3.57
1.07
1.93
| 3.92
1.16
1.79
| 5.93
1.28
2.07
| 3.04
1.42
1.42
| 1.26
0.37
1.22
| ||
LMFA03110011 | 5-iPF2alpha-VI | 1.39
0.968
1.11
| 1.28
0.953
1.05
| 1.3
0.797
0.986
| 1.38
0.985
1.41
| 1.59
1.08
1.24
| 1.43
0.873
1.15
| 1.69
0.86
1.26
| ||
LMFA03040003 | 5S,6S-Lipoxin A4 | 1.03
0.73
0.838
| 1.09
0.829
0.686
| 1.32
0.786
1
| 1.05
0.69
0.714
| 1.33
0.75
0.972
| 1.17
0.714
1
| 1.2
0.92
0.74
| ||
LMFA03050005 | 5(S)-HETrE | 7
0.75
1.75
| 10
0.8
2.8
| 8.8
0.8
4
| 10
1
4.5
| 16
1
4.67
| 4.67
1.33
2
| 2.33
0.333
1
| ||
LMFA03020014 | 6-trans-12-epi-LTB4 | 2.4
0.6
0.8
| 3.25
0.75
1.5
| 3.2
0.8
2.4
| 4
1
2.5
| 4.5
1
2.75
| 4.25
1
2
| 4.67
1
1.33
| ||
LMFA03020013 | 6-trans-LTB4 | 2
0.75
1
| 4.33
1.33
2.33
| 3
1
2.33
| 4
1
1.75
| 3.33
1.33
1.67
| 1.2
0.6
1.4
| 2.25
0.75
0.5
| ||
LMFA04000025 | 7-HDoHE | 1.21
1
1.03
| 1.27
0.962
1.27
| 1.34
0.931
1.03
| 1.48
0.889
1.15
| 1.76
0.96
1.2
| 1.52
0.69
0.828
| 1.36
0.405
0.476
| ||
LMFA03060050 | 8,15-diHETE | 1.11
0.917
1
| 1.25
1.01
1.38
| 2.15
0.895
1.78
| 1.5
0.994
1.24
| 1.18
0.994
1.03
| 1.4
0.899
1.15
| 1.81
1.86
0.827
| ||
LMFA03050006 | 8,9-DiHETrE | 0.833
0.667
1.17
| 1.4
1
1.2
| 1.17
1
1.33
| 1.43
0.857
1
| 2.67
1
1.83
| 2.33
1
1.17
| 1.88
0.625
1.13
| ||
LMFA04000026 | 8-HDoHE | 1.2
0.761
0.935
| 1.17
1.02
1.07
| 1.38
0.917
1
| 1.8
1.12
1.12
| 2.32
1.3
1.27
| 2.44
1.32
0.971
| 2.14
0.551
0.735
| ||
LMFA03060086 | 8-HETE | 1.24
1.09
1.09
| 1.18
1
1.18
| 1.2
0.975
1
| 1.38
1
0.95
| 1.86
0.857
1.03
| 1.76
1.03
0.931
| 1.07
0.305
1.15
| ||
LMFA03050011 | 8-HETrE | 1.17
1
0.833
| 1.17
0.833
1
| 1.83
1
1.17
| 2
1.17
1
| 4.5
1.75
2
| 2.6
1.2
1
| 1.71
0.571
0.857
| ||
LMFA03110001 | 8-iso-PGF2alpha | 0.933
0.933
1.33
| 1.4
1.1
1.9
| 2.57
1.14
2
| 1.83
1.17
3
| 2.54
0.923
1.92
| 2.54
1.31
1.69
| 1.36
0.6
1.2
| ||
LMFA01050278 | 9-HODE | 1.33
2.11
1.22
| 2.12
0.76
0.76
| 3.2
2.7
2.6
| 1.47
1.24
1.71
| 5.5
2.88
3.19
| 1.81
1.22
1.16
| 2.07
0.963
0.593
| ||
LMFA02000024 | 9-HOTrE | 1.4
1.2
0.8
| 2
1.33
2
| 1.75
2
1.25
| 1.4
1.4
0.8
| 1.4
1.2
1
| 1.25
2
1
| 1.6
1.2
1.4
| ||
LMFA01030001 | Arachidonic acid | 1.63
0.836
1.26
| 3.87
1.08
2.06
| 4.66
0.787
2.22
| 7.59
1.57
2.71
| 9.15
1.25
3.19
| 4.33
1.97
1.85
| 1.13
0.301
0.752
| ||
LMFA03010034 | bicyclo-PGE2 | 1.15
0.926
1.04
| 1.04
1.12
1.04
| 1.28
0.96
1
| 1.28
1
0.92
| 1.31
0.962
1.04
| 1.54
0.923
1.19
| 2.63
0.778
1.15
| ||
LMFA03020001 | LTB4 | 3.75
0.75
1
| 6
0.75
2
| 6
0.5
3.5
| 7.33
1
4
| 8
1
3.33
| 3
0.75
1.25
| 2.33
1
1
| ||
LMFA03010049 | PGD1 | 1.28
0.934
0.914
| 1.97
0.933
0.897
| 1.28
0.902
0.926
| 1.34
0.815
0.888
| 1.3
0.801
0.922
| 1.41
0.936
0.988
| 1.72
1.04
1.19
| ||
LMFA03010004 | PGD2 | 62.4
1.95
1.32
| 70.6
2.34
1.89
| 74.8
2.73
1.55
| 68.8
3.05
1.63
| 185
9.88
52.1
| 109
7.25
99.2
| 81.3
6.62
43.9
| ||
LMFA03010142 | PGD3 | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| ||
LMFA03010134 | PGE1 | 2.74
1.66
2.19
| 2.67
1.18
1.4
| 3.34
1.33
1.48
| 3.47
1.07
1.95
| 4.59
1.25
1.7
| 6.75
1.64
3.08
| 7.3
2.14
2.57
| ||
LMFA03010003 | PGE2 | 5
1
1
| 6.33
1
1
| 6.33
1
1.33
| 8.67
1.33
1.33
| 20.3
2.67
6
| 32.7
4.33
18.3
| 87.7
9.67
31.3
| ||
LMFA03010135 | PGE3 | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| ||
LMFA03010137 | PGF1a | 1.79
0.966
1.03
| 2.2
0.703
1.19
| 1.96
1.31
1.16
| 1.51
1
2.09
| 1.76
1.07
0.918
| 2.1
1.06
1.04
| 3.35
0.744
1.54
| ||
LMFA03010002 | PGF2a | 1.23
0.833
0.833
| 1.41
0.815
0.963
| 1.96
1
0.923
| 1.97
0.897
0.931
| 2.78
1.22
1.41
| 2.63
1.04
1.67
| 4.22
1.09
1.91
| ||
LMFA03010019 | PGJ2 | 1.82
0.889
0.847
| 1.52
0.944
0.93
| 2.25
0.958
0.915
| 2.54
0.944
1.03
| 5.21
1.2
1.28
| 6.31
1.26
3.24
| 24.7
1.88
10.9
| ||
LMFA01050143 | Tetranor-12(R)-HETE | 1.02
1.02
0.96
| 0.844
0.759
0.952
| 1.09
0.906
0.928
| 0.923
0.799
0.702
| 0.941
0.677
0.754
| 1.24
0.734
0.702
| 1.99
0.273
0.521
| ||
LMFA03030002 | TxB2 | 1.42
1.03
1.06
| 1.24
0.997
1.03
| 1.54
1.02
1.08
| 1.57
0.986
1.02
| 1.68
0.997
1.14
| 1.62
0.995
1.21
| 2.04
1.03
1.31
| ||
LMFA03030006 | TXB3 | 1.11
0.969
0.804
| 11.9
1.43
0.721
| 2.13
2.05
0.835
| 0.461
0.645
0.605
| 1.25
1.22
0.86
| 1.16
1.61
0.923
| 0.861
1.02
0.443
| ||
- | DNA | 1.01
1.06
1.03
| 0.982
0.83
0.973
| 0.804
1.04
0.965
| 0.673
0.766
0.717
| 0.548
1.09
0.811
| 0.738
0.784
0.876
| 0.648
1.07
0.916
| ||
- | TNF | -
-
-
| 218
164
0.901
| -
-
-
| -
-
-
| -
-
-
| 188
142
158
| 203
131
182
|