Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin
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Sterols
|
Induction
| Details/Graph | LM_ID | Name | Kdo+Comp Kdo Comp 0.5 hrs |
Kdo+Comp Kdo Comp 1 hr |
Kdo+Comp Kdo Comp 2 hrs |
Kdo+Comp Kdo Comp 4 hrs |
Kdo+Comp Kdo Comp 8 hrs |
Kdo+Comp Kdo Comp 12 hrs |
Kdo+Comp Kdo Comp 24 hrs |
|---|---|---|---|---|---|---|---|---|---|
  | LMST01010086 | 22R-hydroxy-cholesterol | -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
| -
-
-
|
| | LMST01010012 | 24,25-epoxy-cholesterol | 0.956
1.01
0.92
| 0.822
0.911
0.874
| 0.905
0.984
0.865
| 0.882
1.13
0.803
| 0.808
1.14
0.712
| 0.688
1.44
0.617
| 0.61
1.31
0.535
|
| | LMST01010018 | 25-hydroxy-cholesterol | 0.787
2.26
0.709
| 0.708
0.735
0.796
| 0.907
0.841
0.935
| 1.51
1.51
0.892
| 1.56
1.78
0.889
| 1.88
2.66
1.38
| 1.5
1.56
1.75
|
| | LMST01010057 | 27-hydroxy-cholesterol | 1.04
0.948
1.09
| 0.836
0.87
1.01
| 1.02
0.921
0.847
| 1.29
0.877
0.832
| 1.59
1.15
1.25
| 0.889
1.04
1.07
| 0.667
0.619
2.25
|
| | LMST01010014 | 4beta-hydroxy-cholesterol | 1
1.43
1.13
| 0.86
1
0.874
| 0.9
0.9
0.977
| 0.917
1.14
1
| 1.23
1.13
1.03
| 1.26
1.43
1.32
| 1.31
1.45
1.26
|
| | LMST01010069 | 7-Dehydrocholesterol | 0.824
0.992
0.71
| 0.811
1.27
0.837
| 0.865
1.14
0.755
| 0.499
1.39
0.514
| 0.536
2.11
0.905
| 1.09
1.92
1.42
| 5.68
1.69
1.29
|
| | LMST01010049 | 7-oxo-cholesterol | 1.12
1.14
0.997
| 0.785
0.926
0.842
| 1
0.917
0.894
| 0.987
1.11
1.04
| 1.06
1.17
1.02
| 1.08
1.21
1.1
| 1.29
1.41
1.07
|
| | LMST01010013 | 7alpha-hydroxy-cholesterol | 1.16
1.74
0.885
| 0.801
0.773
0.841
| 1.1
1.17
1.17
| 0.957
1.17
1.02
| 1.08
0.771
1.28
| 0.986
0.9
1.61
| 0.84
0.835
1.35
|
| | LMST01010015 | Cholestenone | 0.86
0.925
0.9
| 0.773
0.81
0.923
| 0.956
0.949
0.993
| 0.984
0.968
0.892
| 0.902
1.05
0.983
| 0.973
1.22
1.05
| 1.31
1.48
1.02
|
| | LMST01010001 | Cholesterol | 0.937
1
0.93
| 0.897
0.966
0.882
| 0.919
0.899
0.874
| 1.01
1.06
0.982
| 1.15
1.16
1.05
| 1.24
1.32
1.15
| 1.34
1.38
1.2
|
| | LMST01010016 | Desmosterol | 1.01
0.997
0.905
| 0.789
1.02
0.93
| 0.789
1.03
0.686
| 0.534
1.14
0.504
| 0.352
1.44
0.256
| 0.258
1.79
0.185
| 0.218
2.14
0.083
|
| | LMST01010017 | Lanosterol | 0.426
1.42
0.556
| -
-
-
| 0.364
0.848
0.242
| -
-
-
| 0.17
4.41
0.219
| -
-
-
| -
-
-
|
| | - | DNA | 1.09
1.05
1.07
| 1.05
1.01
1.02
| 0.983
1.11
1.08
| 1.04
1.05
1.06
| 1.02
0.972
0.948
| 0.864
0.796
0.901
| 0.653
0.668
0.783
|
| | - | TNF | 1.57
1.35
1.03
| 3.87
9.42
0.914
| 25.2
52.4
0.958
| 135
145
0.756
| 184
182
0.803
| 173
167
0.867
| 165
163
2.24
|