Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin

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11
13.6
1311.3
11.2
14.2
12.613.9
6.4
12.417.9
14
15.215.1
14.914.7
14.516.8
15.416
15.822
1324.7
11.838.9
29.7
4129.5
30.732.5
32.629
27.335.1
25.242
23.138.5
17.820
21.1
1920
16.818.6
1716
14.721.2
15.127.5
13.931.6
11.464.6
50.2
50.1
56.8
46.9
68
79.4
68.4
49.6
146
99
219
85.5
74.5
78.2
130
101
117
183
162
199
389
483
479
428
544
544
495
395
526
152
22.4
29.223.8
16.619.4
3123.1
15.313.6
13.215.1
17.411.8
15.8177
166167
120156
140175
143151
130137
157144
14311.2
14.611.9
8.329.71
15.511.5
7.636.82
6.627.54
8.685.92
7.929.84
10.99.31
7.98.68
9.219.75
9.378.42
8.517.64
10.38
9.423.49
4.914.09
3.255.33
5.555.93
4.393.58
4.885.38
4.244.62
2.724.28
4.044.47
4.073.96
4.544.38
3.744.66
4.014.6
4.194.8
3.395.68
3.855.81
4.553.69
3.184.39
2.983.05
2.887.08
3.733.77
2.934.45
3.874.62
44.77
3.54.01
3.173.34
3.325.38
3.865.13
2.6412.28.228.2111.37.177.938.527.138.778.8211.7118.2110.511.311.310.616.517.514.115.981.591.610110210911995.677.710295.582.711411410580.682.382.777.998.110082.473.56566.721.122.420.620.823.919.717.224.433.220.92025.229.324.528.125.150.930.123.127.135.628.819.91750.425.1171
Details/Graph
LM_ID Name Kdo+Comp
Kdo
Comp
Ctrl
 0 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 0.5 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 1 hr		 Kdo+Comp
Kdo
Comp
Ctrl
 2 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 4 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 8 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 12 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 24 hrs		 Units
. . . .
     (BCI060111)LMSP03010001 C18 Sphingomyelin pmol/ug DNA
     (BCI060122)LMSP03010001 C18 Sphingomyelin pmol/ug DNA
     (BCI060126)LMSP03010001 C18 Sphingomyelin pmol/ug DNA
     (BCI060614)LMSP03010001 C18 Sphingomyelin pmol/ug DNA
     (BCJ060718)LMSP03010001 C18 Sphingomyelin -
-
-
6.02		 6.29
5.37
3.63
3.27		 6.13
6.69
3.46
2.64		 pmol/ug DNA
     (BCJ070123)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCG070319)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCG061213)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCJ070619)LMSP03010001 C18 Sphingomyelin -
-
-
20.1		 11.3
13.5
17.5
11.9		 13.9
12
15
13.3		 pmol/ug DNA
     (BCJ070515)LMSP03010001 C18 Sphingomyelin -
-
-
13.6		 6.44
8.14
9.84
7.25		 7.29
7.31
6.69
6.47		 pmol/ug DNA
     (BCJ070515)LMSP03010001 C18 Sphingomyelin -
-
-
14.4		 7.54
7.14
10.8
8.23		 7.23
6.28
5.4
4.17		 pmol/ug DNA
     (BCD070717)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCD070815)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCISUB000)LMSP03010001 C18 Sphingomyelin -
-
-
230		 pmol/mg protein
     (BCJ080212)LMSP03010001 C18 Sphingomyelin -
-
-
7.39		 7.35
7.98
7.1
7.45		 7.13
7.27
8.38
9.78		 5.27
5.47
5.17
6.8		 6.65
6.75
4.74
5.5		 5.56
5.66
4.1
5.6		 4.54
5.76
5.49
5.04		 4.5
5.32
4.07
4.16		 pmol/ug DNA
     (BCJ080219)LMSP03010001 C18 Sphingomyelin -
-
-
8.41		 7.69
8.67
8.5
7.96		 7.92
8.32
8.61
7.93		 7.5
6.94
7.35
8.38		 6.21
8.23
6.85
6.16		 4.88
5.77
6.42
5.53		 5.33
4.25
5.32
4.13		 5.07
5.62
6.74
4.7		 pmol/ug DNA
     (BCJ080226)LMSP03010001 C18 Sphingomyelin -
-
-
5.87		 7.26
7.25
6.55
5.05		 5.35
5.71
5.23
5.79		 6.43
5.68
5.86
6.7		 5.3
5.83
5.91
4.97		 4.05
3.74
3.66
4.38		 3.27
3.94
3.38
3.04		 4.07
3.33
3.36
2.83		 pmol/ug DNA
     (BCD090127)LMSP03010001 C18 Sphingomyelin -
-
-
6.57		 5.04
7.66
6.59
5.57		 6.24
6.32
5.88
5.07		 6.54
5.87
5.85
6.82		 6.15
7.4
6.86
7.63		 9.09
8.6
8.48
5.72		 10.7
7.14
6.38
6.67		 10.8
8.85
8
6.61		 pmol/ug DNA
     (BCD090114)LMSP03010001 C18 Sphingomyelin -
-
-
6.72		 6.25
5.72
5.75
7.48		 6.46
6.71
5.53
5.95		 5.54
5.78
5.74
6.46		 6.04
7.17
5.54
6.04		 6.57
6.84
5.29
6.91		 7.08
8.63
6.19
5.82		 6.45
5.92
7.49
6.96		 pmol/ug DNA
     (BCD090401)LMSP03010001 C18 Sphingomyelin -
-
-
9.28		 8.45
9.32
8.95
9.83		 9.18
10.1
10.5
9.49		 9.27
9.62
8.39
9.6		 6.76
8.93
7.02
6.45		 7.87
7.74
6.63
6.31		 5.52
6.27
5.83
7.55		 7.45
5.58
6.02
5.78		 pmol/ug DNA
     (BCD090512)LMSP03010001 C18 Sphingomyelin -
-
-
23.7		 pmol/ug DNA
     (BCD090512)LMSP03010001 C18 Sphingomyelin -
-
-
148		 pmol/sample
     (BCJ081209)LMSP03010001 C18 Sphingomyelin -
-
-
2.62		 1.84
-
1.74
2.04		 2.83
2.29
2.38
2.38		 1.74
1.74
2.13
2.08		 2.89
2.06
1.78
1.97		 2.1
2.02
3.11
1.85		 2.11
2.37
2.08
2.36		 2.12
3.23
2.68
3.46		 pmol/ug DNA
     (BCD090512)LMSP03010001 C18 Sphingomyelin -
-
-
11.8		 pmol/ug DNA
     (BCD090512)LMSP03010001 C18 Sphingomyelin -
-
-
9.73		 pmol/ug DNA
     (BCD090716)LMSP03010001 C18 Sphingomyelin -
-
-
3.98		 pmol/ug DNA
     (BCD090716)LMSP03010001 C18 Sphingomyelin -
-
-
4.75		 pmol/ug DNA
     (BCD090805)LMSP03010001 C18 Sphingomyelin -
-
-
4.17		 pmol/ug DNA
     (BCD090805)LMSP03010001 C18 Sphingomyelin -
-
-
3.6		 pmol/ug DNA
     (BCD100322)LMSP03010001 C18 Sphingomyelin -
-
-
9.17		 pmol/ug DNA
     (BCD100427)LMSP03010001 C18 Sphingomyelin -
-
-
11.6		 pmol/ug DNA
     (BCD100624)LMSP03010001 C18 Sphingomyelin -
-
-
9.75		 pmol/ug DNA
     (BCD100322)LMSP03010001 C18 Sphingomyelin -
-
-
93.8		 pmol/sample
     (BCD100427)LMSP03010001 C18 Sphingomyelin -
-
-
109		 pmol/sample
     (BCD100624)LMSP03010001 C18 Sphingomyelin -
-
-
72.8		 pmol/sample
     (BCD110605)LMSP03010001 C18 Sphingomyelin -
-
-
60.8		 pmol/sample
     (BCD110605)LMSP03010001 C18 Sphingomyelin -
-
-
13.1		 pmol/10E6 cells
     (BCG120120)LMSP03010001 C18 Sphingomyelin -
-
-
22.7		 pmol/10E6 cells
     (BCG120131)LMSP03010001 C18 Sphingomyelin -
-
-
28.7		 pmol/10E6 cells
     (BCG120131)LMSP03010001 C18 Sphingomyelin -
-
-
45.4		 pmol/10E6 cells
     (BCG120308)LMSP03010001 C18 Sphingomyelin -
-
-
53.6		 pmol/10E6 cells
     (NASH0007)LMSP03010001 C18 Sphingomyelin -
-
-
42		 -
-
-
62.7		 -
-
-
95.3		 -
-
-
87.6		 -
-
-
58.4		 -
-
-
70.8		 -
-
-
79.7		 -
-
-
49.2		 -
-
-
104		 -
-
-
32.4		 pmol/mg
     (NASH0010)LMSP03010001 C18 Sphingomyelin -
-
-
6016		 -
-
-
2641		 -
-
-
5360		 -
-
-
6591		 -
-
-
3126		 -
-
-
5055		 -
-
-
7972		 -
-
-
3830		 -
-
-
8880		 -
-
-
7656		 pmol/ml
     (NASH0001)LMSP03010001 C18 Sphingomyelin -
-
-
27.7		 -
-
-
111		 -
-
-
17.4		 -
-
-
27.8		 -
-
-
16.1		 -
-
-
160		 -
-
-
22.4		 -
-
-
37.8		 -
-
-
99.5		 -
-
-
35.1		 pmol/ml
     (BCJ070122)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCJ070124)LMSP03010001 C18 Sphingomyelin pmol/1E6 cells
     (BCISUB300)LMSP03010001 C18 Sphingomyelin -
-
-
231		 pmol/mg protein