Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin

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113
146
122113
111
126
111110
48.9
15698.1
78.2
86.790.8
82.486.7
84.890.6
9694.7
91.9104
100120
121168
133
164133
140144
145131
136155
148176
151166
16566.3
67.4
62.967.2
6260.1
67.655.9
54.265.3
74.285.7
68109
82.8516
562
795
596
540
804
635
672
1010
1158
651
1723
541
606
476
742
825
835
1151
1045
995
2818
3401
3361
3719
2932
3659
3333
2808
3722
1366
177
197181
133157
239176
118102
118124
134103
1261393
11191273
9641266
10831335
11051136
11551135
12071258
113888.3
98.390.7
66.778.7
11987.9
59.151.1
5962.2
66.951.7
62.977.5
73.570.8
63.370.4
71.174.3
72.663.2
75.963.1
79.370
74.824.3
3730.5
26.842
41.742.2
30.623.7
32.530.4
30.228.8
20.729.8
30.533.4
33.531.2
34.231.2
26.130.9
26.725.9
29.830
25.940.2
24.834
30.723
21.326
20.421.9
17.740.6
2422.3
21.231.5
2527
2729.7
23.423.7
21.723.9
20.330.8
24.830.2
19.163.142.340.354.835.738.645.128.336.447.665.739.438.542.963.371.966.910210287.21224214714944965405795073094225154664095334314505255224825736186304524104773063383052853462862483144443283243534614954924804002812262833383262492474192831487
Details/Graph
LM_ID Name Kdo+Comp
Kdo
Comp
Ctrl
 0 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 0.5 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 1 hr		 Kdo+Comp
Kdo
Comp
Ctrl
 2 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 4 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 8 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 12 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 24 hrs		 Units
. . . .
     (BCI060111)LMSP03010007 C24:1 Sphingomyelin pmol/ug DNA
     (BCI060122)LMSP03010007 C24:1 Sphingomyelin pmol/ug DNA
     (BCI060126)LMSP03010007 C24:1 Sphingomyelin pmol/ug DNA
     (BCI060614)LMSP03010007 C24:1 Sphingomyelin pmol/ug DNA
     (BCJ060718)LMSP03010007 C24:1 Sphingomyelin -
-
-
41.4		 46
34.8
34.7
32.9		 44.5
45.9
43.8
35.5		 pmol/ug DNA
     (BCJ070123)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCG070306)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCG061213)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCJ070619)LMSP03010007 C24:1 Sphingomyelin -
-
-
187		 156
155
260
195		 165
157
236
232		 pmol/ug DNA
     (BCJ070515)LMSP03010007 C24:1 Sphingomyelin -
-
-
163		 102
101
151
114		 96.9
88.3
111
124		 pmol/ug DNA
     (BCJ070515)LMSP03010007 C24:1 Sphingomyelin -
-
-
34		 19.1
17.1
24.9
18.9		 16.7
16
13.5
10.6		 pmol/ug DNA
     (BCD070717)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCD070815)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCISUB000)LMSP03010007 C24:1 Sphingomyelin -
-
-
2155		 pmol/mg protein
     (BCJ080212)LMSP03010007 C24:1 Sphingomyelin -
-
-
72.9		 66
71.1
64.1
67.4		 57.4
62.8
75.9
92.6		 56.3
48.8
51.7
54.1		 68.7
74.4
41.5
55.7		 62.5
59
57.2
71.5		 58.1
67.3
80.9
68.1		 52.4
63.2
63.6
71.6		 pmol/ug DNA
     (BCJ080219)LMSP03010007 C24:1 Sphingomyelin -
-
-
73		 73.4
97.4
87
77.9		 75
82.2
86.1
76.2		 75.5
61.8
72.2
78.4		 64.8
83.8
72.3
63.2		 54.2
61.5
79.3
68.4		 67.8
55.5
69.5
60.1		 53.4
59.6
105
74.8		 pmol/ug DNA
     (BCJ080226)LMSP03010007 C24:1 Sphingomyelin -
-
-
62.3		 77.2
74.5
67
51.6		 56.8
60.4
55.7
58.1		 69
56.3
55.5
66.8		 62
59.8
62.1
55.3		 45
44.4
47.2
54.7		 39.8
47.9
43.5
40.8		 42.8
38.8
56
55.1		 pmol/ug DNA
     (BCD090127)LMSP03010007 C24:1 Sphingomyelin -
-
-
148		 126
169
138
134		 157
138
138
103		 152
150
160
148		 137
164
161
161		 181
195
160
124		 215
148
148
153		 235
210
176
147		 pmol/ug DNA
     (BCD090114)LMSP03010007 C24:1 Sphingomyelin -
-
-
125		 109
108
94.3
145		 117
119
103
108		 98
110
113
118		 107
130
109
114		 105
141
100
130		 117
166
132
104		 129
105
137
133		 pmol/ug DNA
     (BCD090401)LMSP03010007 C24:1 Sphingomyelin -
-
-
211		 169
169
169
176		 190
197
211
180		 194
196
159
173		 129
185
144
127		 158
161
129
136		 121
138
111
152		 183
134
116
121		 pmol/ug DNA
     (BCD090512)LMSP03010007 C24:1 Sphingomyelin -
-
-
216		 pmol/ug DNA
     (BCD090512)LMSP03010007 C24:1 Sphingomyelin -
-
-
1350		 pmol/sample
     (BCJ081209)LMSP03010007 C24:1 Sphingomyelin -
-
-
54.1		 41.6
-
33.3
40.6		 59
54.3
52.7
47.4		 50.9
40.7
50.3
45.2		 70
49.2
49.8
48.8		 50.6
48.4
76.3
54		 49.2
57
62.5
63.6		 59.7
79.8
71.7
75.1		 pmol/ug DNA
     (BCD090512)LMSP03010007 C24:1 Sphingomyelin -
-
-
108		 pmol/ug DNA
     (BCD090512)LMSP03010007 C24:1 Sphingomyelin -
-
-
88.7		 pmol/ug DNA
     (BCD090716)LMSP03010007 C24:1 Sphingomyelin -
-
-
28.1		 pmol/ug DNA
     (BCD090716)LMSP03010007 C24:1 Sphingomyelin -
-
-
33.6		 pmol/ug DNA
     (BCD090805)LMSP03010007 C24:1 Sphingomyelin -
-
-
29.4		 pmol/ug DNA
     (BCD090805)LMSP03010007 C24:1 Sphingomyelin -
-
-
25.4		 pmol/ug DNA
     (BCD100322)LMSP03010007 C24:1 Sphingomyelin -
-
-
49.4		 pmol/ug DNA
     (BCD100427)LMSP03010007 C24:1 Sphingomyelin -
-
-
51		 pmol/ug DNA
     (BCD100624)LMSP03010007 C24:1 Sphingomyelin -
-
-
58.4		 pmol/ug DNA
     (BCD100322)LMSP03010007 C24:1 Sphingomyelin -
-
-
505		 pmol/sample
     (BCD100427)LMSP03010007 C24:1 Sphingomyelin -
-
-
479		 pmol/sample
     (BCD100624)LMSP03010007 C24:1 Sphingomyelin -
-
-
435		 pmol/sample
     (BCD110605)LMSP03010007 C24:1 Sphingomyelin -
-
-
383		 pmol/sample
     (BCD110605)LMSP03010007 C24:1 Sphingomyelin -
-
-
222		 pmol/10E6 cells
     (BCG120120)LMSP03010007 C24:1 Sphingomyelin -
-
-
311		 pmol/10E6 cells
     (BCG120131)LMSP03010007 C24:1 Sphingomyelin -
-
-
396		 pmol/10E6 cells
     (BCG120131)LMSP03010007 C24:1 Sphingomyelin -
-
-
451		 pmol/10E6 cells
     (BCG120308)LMSP03010007 C24:1 Sphingomyelin -
-
-
385		 pmol/10E6 cells
     (NASH0006)LMSP03010007 C24:1 Sphingomyelin -
-
-
148		 -
-
-
60.8		 -
-
-
209		 -
-
-
159		 -
-
-
175		 -
-
-
204		 -
-
-
196		 -
-
-
122		 -
-
-
158		 -
-
-
137		 pmol/mg
     (NASH0010)LMSP03010007 C24:1 Sphingomyelin -
-
-
12251		 -
-
-
15323		 -
-
-
9668		 -
-
-
12644		 -
-
-
14281		 -
-
-
12232		 -
-
-
9180		 -
-
-
12337		 -
-
-
15095		 -
-
-
11864		 pmol/ml
     (NASH0010)LMSP03010007 C24:1 Sphingomyelin -
-
-
142		 -
-
-
117		 -
-
-
156		 -
-
-
62		 -
-
-
69.8		 -
-
-
46.5		 -
-
-
340		 -
-
-
578		 -
-
-
321		 -
-
-
87.5		 pmol/ml
     (BCJ070122)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCJ070124)LMSP03010007 C24:1 Sphingomyelin pmol/1E6 cells
     (BCISUB300)LMSP03010007 C24:1 Sphingomyelin -
-
-
2123		 pmol/mg protein