Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin

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19
31.926.7
2316.6
38.219.2
137.55
10.114.9
15.714.2
13.616.7
23.920.9
21.814.8
22.716.3
15.99.33
1315.1
18.619.2
16.216.5
12.35.33
3.658.66
6.6213.7
119.22
10.815.7
11.334.4
72.520.2
10.15.83
4.576.44
5.4310.1
9.4212
8.8613.4
11.135.7
90.616.8
6.083.59
10.3-
-17
3.6511.9
13.222.6
-12.2
-13.2
6.122.85
9.04-
-15.5
3.8813
15.217.2
-16.6
-3021.921.416.711.614.62329.138.325.640.621.919.422.212.110.77.8414.821.222.710.720024426215117622025831844427728722826822385.87861.269.811916155.115014617112812284.258.732.517017514415817016996.87528416413913915713258.746.223468.70.385
0.35
0.430.465
0.330.36
0.270.375
0.2950.23
0.220.305
0.2810.6
1.95
3.59.05
11.510.9
7.553.9
5.159
5.18.9
9.459.3
3.556.65
5.6
5.55.1
4.98.1
3.257.55
5.155.3
3.67.8
4.255.05
4.17.9
6.4
6.558.35
4.157.45
5.256.8
4.85.2
48.75
4.53.95
1.4585.5
74.8
96
83.3
96.7
69.2
73.1
90.8
74.1
201
262
157
78.8
69.3
67
126
108
115
574
553
548
Details/Graph
LM_ID Name Kdo+Comp
Kdo
Comp
Ctrl
 0 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 0.5 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 1 hr		 Kdo+Comp
Kdo
Comp
Ctrl
 2 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 4 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 8 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 12 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 24 hrs		 Units
. . . .
     (MSH090825) PC(36:4) -
-
-
26.3		 pmol/ug DNA
     (MSH090825) PC(36:4) -
-
-
21.6		 pmol/ug DNA
     (MSH090825) PC(36:4) -
-
-
17.3		 pmol/ug DNA
     (MSH090825) PC(36:4) -
-
-
20.7		 pmol/ug DNA
     (MSH090825) PC(36:4) -
-
-
5.38		 pmol/ug DNA
     (MSH090825) PC(36:4) -
-
-
4.65		 pmol/ug DNA
     (BCD100322) PC(36:4) -
-
-
24.4		 pmol/ug DNA
     (BCD100427) PC(36:4) -
-
-
50.1		 pmol/ug DNA
     (BCD100624) PC(36:4) -
-
-
15.5		 pmol/ug DNA
     (BCD100322) PC(36:4) -
-
-
249		 pmol/sample
     (BCD100427) PC(36:4) -
-
-
471		 pmol/sample
     (BCD100624) PC(36:4) -
-
-
115		 pmol/sample
     (BCG120120) PC(36:4) -
-
-
160		 pmol/10E6 cells
     (BCG120131) PC(36:4) -
-
-
203		 pmol/10E6 cells
     (BCG120212) PC(36:4) -
-
-
263		 pmol/10E6 cells
     (BCG120308) PC(36:4) -
-
-
306		 pmol/10E6 cells
     (BCH050817) PC(36:4) -
-
-
0.48		 Normalized Int
     (MSH060201) PC(36:4) -
-
-
5.2		 pmol/ug DNA
     (MSH060208) PC(36:4) -
-
-
6		 pmol/ug DNA
     (MSH060215) PC(36:4) -
-
-
7.05		 pmol/ug DNA
     (BCJ060718) PC(36:4) -
-
-
8.3		 5.1
4.8
2.5
2.17		 4.89
4
1.59
1.05		 pmol/ug DNA
     (BCJ070122) PC(36:4) pmol/1E6 cells
     (BCJ070123) PC(36:4) pmol/1E6 cells
     (BCG070312) PC(36:4) pmol/1E6 cells
     (BCG061213) PC(36:4) pmol/1E6 cells
     (BCJ070619) PC(36:4) -
-
-
15.5		 6.24
8.23
6.46
5.19		 5.74
5.63
4.77
4.24		 pmol/ug DNA
     (BCJ070619) PC(36:4) -
-
-
8.58		 6.05
6.09
5.14
5.01		 5.37
7.4
4.26
3.47		 pmol/ug DNA
     (MSH070829) PC(36:4) pmol/1E6 cells
     (MSH070918) PC(36:4) pmol/1E6 cells
     (BCHSUB000) PC(36:4) -
-
-
512		 pmol/mg protein
     (BCJ080212) PC(36:4) -
-
-
4.19		 1.1
1.45
1.02
1.56		 1.13
2.23
1.65
1.69		 2.04
2.75
2.77
-		 3.37
1.21
1.28
1.82		 1.47
2.04
1.04
1.97		 2.23
2.21
1.48
1.5		 1.41
2.19
-
-		 pmol/ug DNA
     (BCJ080226) PC(36:4) -
-
-
7.47		 7.79
7.75
8.48
7.01		 10.7
9.01
8.48
7.26		 13.4
10.4
8.4
9.56		 9.18
10.4
7.33
8.12		 6.24
7.94
6.07
5.52		 7
8.79
3.31
3.08		 4.1
3.5
2.68
3.17		 pmol/ug DNA
     (BCJ080226) PC(36:4) -
-
-
14		 -
11.5
9.83
8.98		 -
-
8.37
8.23		 9.32
9.59
-
11		 -
-
-
9.28		 6.27
-
-
-		 -
-
-
-		 -
-
-
-		 pmol/ug DNA
     (BCJ080304) PC(36:4) -
-
-
11.3		 9.48
13.5
9.63
12.6		 12.3
16
8.92
7.88		 9.61
10.5
6.09
8.78		 5.7
11.9
7.44
5.61		 5.17
9.24
4.46
5.74		 4.06
8.86
2.85
3.52		 4.48
5.1
-
4.01		 pmol/ug DNA
     (BCJ080805) PC(36:4) -
-
-
25.4		 24.9
13.6
19.8
23		 20.7
18.6
9.34
17.7		 20
19.7
16.7
20		 18.3
14.2
13.2
14.1		 14.7
19.3
9.87
9.78		 20.8
15
7.19
-		 16.6
20.7
7.16
9.61		 pmol/ug DNA
     (BCISUB100) PC(36:4) -
-
-
477		 pmol/mg protein
     (BCISUB200) PC(36:4) -
-
-
485		 pmol/mg protein
     (BCH081021) PC(36:4) -
-
-
41.2		 32.7
49.8
48.2
77.6		 47.1
40.9
44.5
44		 37.4
38.6
-
37.6		 54.7
41.8
49.7
39.7		 38
41
38.9
35.9		 54.6
43.8
55.7
59.2		 65
48.5
49.7
54.1		 pmol/ug DNA
     (BCH081028) PC(36:4) -
-
-
47.5		 85.2
56.6
54.8
52.3		 50.2
57.1
62.4
55.6		 57.2
72.2
64.7
73		 45.6
49.2
60.1
58		 72
46.2
57.3
49		 67.3
81
61.9
67.9		 54.6
59.1
40.9
39.5		 pmol/ug DNA
     (BCH081209) PC(36:4) -
-
-
58.9		 32.3
37.3
38.8
40.4		 39.4
43.7
37
39.9		 42.8
36.5
39.6
42.7		 44.1
41.4
44.1
42.2		 50.3
40.2
43
40.9		 37.2
48.7
44.4
60.4		 46.5
54
53.3
46.1		 pmol/ug DNA
     (BCD110605) PC(36:4) -
-
-
55.3		 pmol/10E6 cells
     (NASH0014) PC(36:4) -
-
-
68.5		 -
-
-
-		 -
-
-
85.7		 -
-
-
34		 -
-
-
46.2		 -
-
-
89.2		 -
-
-
141		 -
-
-
31.4		 -
-
-
35		 -
-
-
-		 -
-
-
118		 -
-
-
31.7		 -
-
-
95.6		 -
-
-
90.5		 -
-
-
35.5		 -
-
-
107		 -
-
-
54.5		 -
-
-
106		 pmol/mg
     (NASH0014) PC(36:4) -
-
-
563837		 -
-
-
492323		 -
-
-
335326		 -
-
-
203396		 -
-
-
380123		 -
-
-
180018		 -
-
-
513095		 -
-
-
511935		 -
-
-
438313		 -
-
-
360681		 -
-
-
588102		 -
-
-
249138		 -
-
-
116051		 -
-
-
453799		 -
-
-
349031		 -
-
-
593696		 -
-
-
222414		 -
-
-
518811		 pmol/ml