Gene/Proteome Database (LMPD)

LMPD ID
LMP000018
Gene ID
16889
Species
Mus musculus (Mouse)
Gene Name
lysosomal acid lipase A
Gene Symbol
Lipa
Synonyms
AA960673; Lal; Lip-1; Lip1
Chromosome
19
Map Location
19 C1|19

Proteins

lysosomal acid lipase/cholesteryl ester hydrolase precursor
Refseq ID NP_067435
Protein GI 161760651
UniProt ID Q3TEL5
mRNA ID NM_021460
Length 397
RefSeq Status VALIDATED
MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ
sig_peptide: 1..25 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (Q9Z0M5.2) calculated_mol_wt: 2677 peptide sequence: MQLQGLVFVFTIGILLSRVPTGTVS mat_peptide: 26..397 product: Lysosomal acid lipase/cholesteryl ester hydrolase experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9Z0M5.2) calculated_mol_wt: 42666 peptide sequence: AVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ sig_peptide: 1..25 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (Q9Z0M5.2) calculated_mol_wt: 2677 peptide sequence: MQLQGLVFVFTIGILLSRVPTGTVS mat_peptide: 26..397 product: Lysosomal acid lipase/cholesteryl ester hydrolase experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9Z0M5.2) calculated_mol_wt: 42666 peptide sequence: AVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ
lysosomal acid lipase/cholesteryl ester hydrolase precursor
Refseq ID NP_001104570
Protein GI 162287343
UniProt ID Q3TEL5
mRNA ID NM_001111100
Length 397
RefSeq Status VALIDATED
Protein sequence is identical to GI:161760651 (mRNA isoform)

Gene Information

Entrez Gene ID
16889
Gene Name
lysosomal acid lipase A
Gene Symbol
Lipa
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016788 IEA:InterPro F hydrolase activity, acting on ester bonds
GO:0000902 IMP:MGI P cell morphogenesis
GO:0008283 IMP:MGI P cell proliferation
GO:0001816 IMP:MGI P cytokine production
GO:0048873 IMP:MGI P homeostasis of number of cells within a tissue
GO:0006954 IMP:MGI P inflammatory response
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0030324 IMP:MGI P lung development
GO:0048771 IMP:MGI P tissue remodeling

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR025483 Lipase, eukaryotic
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
lysosomal acid lipase A
Protein Entry
LICH_MOUSE
UniProt ID
Q3TEL5
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP000018 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
161760651 RefSeq NP_067435 397 lysosomal acid lipase/cholesteryl ester hydrolase precursor

Identical Sequences to LMP000018 proteins

Reference Database Accession Length Protein Name
GI:161760651 DBBJ BAC40484.1 397 unnamed protein product [Mus musculus]
GI:161760651 DBBJ BAE29088.1 397 unnamed protein product [Mus musculus]
GI:161760651 DBBJ BAE37585.1 397 unnamed protein product [Mus musculus]
GI:161760651 GenBank EDL41750.1 397 lysosomal acid lipase 1 [Mus musculus]
GI:161760651 RefSeq NP_001104570.1 397 lysosomal acid lipase/cholesteryl ester hydrolase precursor [Mus musculus]
GI:161760651 SwissProt Q9Z0M5.2 397 RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase; Short=Acid cholesteryl ester hydrolase; Short=LAL; AltName: Full=Cholesteryl esterase; AltName: Full=Lipase A; AltName: Full=Sterol esterase; Flags: Precursor [Mus musculus]

Related Sequences to LMP000018 proteins

Reference Database Accession Length Protein Name
GI:161760651 DBBJ BAE41233.1 397 unnamed protein product [Mus musculus]
GI:161760651 EMBL CAA83494.1 397 lysosomal acid lipase [Mus musculus]
GI:161760651 GenBank AAH58564.1 397 Lysosomal acid lipase A [Mus musculus]
GI:161760651 GenBank EDM13161.1 397 lysosomal acid lipase 1, isoform CRA_a [Rattus norvegicus]
GI:161760651 GenBank EDM13162.1 397 lysosomal acid lipase 1, isoform CRA_a [Rattus norvegicus]
GI:161760651 RefSeq XP_008758543.1 397 PREDICTED: lysosomal acid lipase/cholesteryl ester hydrolase isoform X1 [Rattus norvegicus]