Gene/Proteome Database (LMPD)

LMPD ID
LMP000160
Gene ID
18559
Species
Mus musculus (Mouse)
Gene Name
phosphatidylcholine transfer protein
Gene Symbol
Pctp
Synonyms
PC-TP; StarD2
Alternate Names
phosphatidylcholine transfer protein; START domain-containing protein 2; stAR-related lipid transfer protein 2
Chromosome
11
Map Location
11 C|11 54.7 cM

Proteins

phosphatidylcholine transfer protein
Refseq ID NP_032822
Protein GI 117320552
UniProt ID P53808
mRNA ID NM_008796
Length 214
RefSeq Status VALIDATED
MAGAACCFSDEQFREACAELQKPALTGADWQLLVEASGITIYRLLDQPSGLYEYKVFGVLEGCSPALLADVYMDLDYRKQWDQYVKELYEKESDEQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDGRKIYVVLAQSISAPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMVKACQNYHKKT

Gene Information

Entrez Gene ID
18559
Gene Name
phosphatidylcholine transfer protein
Gene Symbol
Pctp
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0031210 ISS:UniProtKB F phosphatidylcholine binding
GO:0008525 ISS:UniProtKB F phosphatidylcholine transporter activity
GO:0008203 IMP:MGI P cholesterol metabolic process
GO:0015914 ISS:UniProtKB P phospholipid transport

Domain Information

InterPro Annotations

Accession Description
IPR023393 START-like domain
IPR002913 START_lipid-bd_dom

UniProt Annotations

Entry Information

Gene Name
phosphatidylcholine transfer protein
Protein Entry
PPCT_MOUSE
UniProt ID
P53808
Species
Mouse

Comments

Comment Type Description
Function Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
Similarity Contains 1 START domain. {ECO:0000255|PROSITE- ProRule:PRU00197}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10500206}.
Subunit Interacts with ACOT13/THEM2. {ECO:0000269|PubMed:17704541}.
Tissue Specificity Abundant in liver of pups but levels in liver decrease 10-fold about 2 weeks after birth. In adult, highly expressed in epididymis, testis, kidney and bone-marrow derived mast cells. {ECO:0000269|PubMed:10500206}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000160 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
117320552 RefSeq NP_032822 214 phosphatidylcholine transfer protein

Identical Sequences to LMP000160 proteins

Reference Database Accession Length Protein Name
GI:117320552 GenBank AAI40285.1 214 Phosphatidylcholine transfer protein, partial [synthetic construct]
GI:117320552 GenBank AAI56714.1 214 Phosphatidylcholine transfer protein [synthetic construct]

Related Sequences to LMP000160 proteins

Reference Database Accession Length Protein Name
GI:117320552 GenBank AAF02537.1 214 phosphatidylcholine transfer protein [Mus musculus]
GI:117320552 GenBank EDL15879.1 214 phosphatidylcholine transfer protein, isoform CRA_b [Mus musculus]
GI:117320552 RefSeq NP_058921.1 214 phosphatidylcholine transfer protein [Rattus norvegicus]
GI:117320552 RefSeq XP_005350578.1 214 PREDICTED: phosphatidylcholine transfer protein [Microtus ochrogaster]
GI:117320552 RefSeq XP_006972080.1 214 PREDICTED: phosphatidylcholine transfer protein [Peromyscus maniculatus bairdii]
GI:117320552 SwissProt P53808.2 214 RecName: Full=Phosphatidylcholine transfer protein; Short=PC-TP; AltName: Full=START domain-containing protein 2; Short=StARD2; AltName: Full=StAR-related lipid transfer protein 2 [Mus musculus]