Oxidized Phospholipids Search

Search a computationally-generated database of oxidized phospholipid classes with a list of precursor ions

A virtual database composed of major classes of oxidized lipid species has been generated from a list of commonly occurring acyl/alkyl chains (listed below). Chain positions and double bond regiochemistry and geometry are not specified. Search the database by entering a list of precursor ion m/z values in the text box, optionally restrict the search to certain lipid classes and then select an appropriate ion type and mass tolerance range.

Step 1

Provide a list of m/z values.

OR

Step 2

Choose at least one ion adduct with appropriate polarity

Positive Mode
Negative Mode
Neutral Mass
Note: This option is for testing/QC purposes only.

Step 3

Step 4

Restrict search by

Phospholipid Headgroup
Precursor of Oxidized Acyl Chain

Step 5

Limit search to certain sn1 (non-oxidized) chains

Step 6

The sn1 acyl/alkyl chains used to create the database of oxidized glycerophospholipids:

14:0 14:1 16:0 16:1 18:0 18:1 18:2 18:3 18:4 20:0 20:1 20:2 20:3 20:4 20:5 22:0 22:1 22:2 22:4 22:5 22:6
O-16:0 O-18:0 O-20:0 P-16:0 P-18:0 P-20:0 P-16:1 P-18:1 P-20:1

The abbreviations used for the sn2 oxidized chains:
Abbreviation Name Precursor (#Carbons)
KDdiA 9-Keto-10-Dodecene-1,12-Dioic Acid C18
HDdiA 9-Hydroxy-10-Dodecene-1,12-Dioic Acid C18
KODA 9-Keto(12-Oxo)-10-Dodecenoic Acid C18
HODA 9-Hydroxy(12-Oxo)-10-Dodecenoic Acid C18
ON 9-Oxo-nonanoic acid C18
Aze Azeleic acid (Nonane-1,9-dioic acid) C18
HOTrE Hydroxy-OctadecaTriEnoic acid C18
DiHODE DiHydroxy-OctadecaDiEnoic acid C18
HODE Hydroxy-OctadecaDiEnoic acid C18
EpODE Epoxy-OctadecaDiEnoic acid C18
OxoODE Oxo-OctadecaDiEnoic acid C18
HOME Hydroxy-Octadeca(Mono)Enoic acid C18
DiHOME DiHydroxy-Octadeca(Mono)Enoic acid C18
EpOME Epoxy-Octadeca(Mono)Enoic acid C18
- 8-Oxo-octanoic acid C18
- 8-Carboxy-octanoic acid C18
- 11-Oxo-9-undecenoic acid C18
- 13-Oxo-9,11-tridecedienoic acid C18
- 8-Keto-13-oxo-9,11-tridecedienoic acid C18
- 8-Hydroxy-13-oxo-9,11-tridecedienoic acid C18
- 2-furyl-octanoic acid C18
KODiA 5-Keto-6E-Octene-1,8-Dioic Acid C20
HODiA 5-Hydroxy-6E-Octene-1,8-Dioic Acid C20
KOOA 5-Keto(8-Oxo)-6E-Octenoic Acid C20
HOOA 5-Hydroxy(8-Oxo)-6E-Octenoic Acid C20
OV 5-Oxovaleric acid C20
G Glutaric acid C20
PGD2 PGD2 C20
PGE2 PGE2 C20
EI Epoxy-IsoProstaglandin E2 C20
EP Epoxy-cycloPentenone (PGA2) C20
OxoETE Oxo-EicosaTetraEnoic acid C20
HETE Hydroxy-EicosaTetraEnoic acid C20
DiHETE DiHydroxy-EicosaTetraEnoic acid C20
EpETE Epoxy-EicosaTetraEnoic acid C20
HEDE Hydroxy-EicosaDiEnoic acid C20
HETrE Hydroxy-EicosaTriEnoic acid C20
DiHETrE DiHydroxy-EicosaTriEnoic acid C20
EpETrE Epoxy-EicosaTriEnoic acid C20
HEPE Hydroxy-EicosaPentaEnoic acid C20
DiHEPE DiHydroxy-EicosaPentaEnoic acid C20
- PGF2 C20
- LGD2 C20
- LGE2 C20
- IsoFuran C20
- 4-Keto-9-oxo-5,7-nonadienoic acid C20
- 5,10-Dihydroxy-11-oxo-6,8-undecedienoic acid C20
- 10-Hydroxy-13-oxo-5,8,11-tridecatrienoic acid C20
- Acetic acid C20
- Butanoic acid C20
- 3-Butenoic acid C20
- 2-furyl-butanoic acid C20
KHdiA 4-Keto-5-Heptene-1,7-Dioic Acid C22
HHdiA 4-HydroxyHeptene-1,7-Dioic Acid C22
KOHA 4-Keto(7-Oxo)Heptenoic Acid C22
HOHA 4-Hydroxy(7-Oxo)Heptenoic Acid C22
OB 4-Oxobutyric acid C22
S Succinic acid C22
EpDoPE Epoxy-DocosaPentaEnoic acid C22
HDoTE Hydroxy-DocosaTetraEnoic acid C22
HDoPE Hydroxy-DocosaPentaEnoic acid C22
DiHDoPE DiHydroxy-DocosaPentaEnoic acid C22
HDoHE Hydroxy-DocosaHexaEnoic acid C22
EpDoHE Epoxy-DocosaHexaEnoic acid C22
DiHDoHE DiHydroxy-DocosaHexaEnoic acid C22
- 6-oxo-4-hexenoic acid C22
- 2-furyl-propanoic acid C22