Gene/Proteome Database (LMPD)

LMPD ID
LMP000296
Gene ID
22259
Species
Mus musculus (Mouse)
Gene Name
nuclear receptor subfamily 1, group H, member 3
Gene Symbol
Nr1h3
Synonyms
AU018371; LXR; RLD1; Unr1
Chromosome
2
Map Location
2 E1|2 50.52 cM

Proteins

oxysterols receptor LXR-alpha
Refseq ID NP_038867
Protein GI 110625616
UniProt ID Q91X41
mRNA ID NM_013839
Length 445
RefSeq Status VALIDATED
MSLWLEASMPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGVALGIGLESAEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYVCHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDPLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
oxysterols receptor LXR-alpha
Refseq ID NP_001171201
Protein GI 295148193
UniProt ID Q91X41
mRNA ID NM_001177730
Length 445
RefSeq Status VALIDATED
Protein sequence is identical to GI:110625616 (mRNA isoform)

Gene Information

Entrez Gene ID
22259
Gene Name
nuclear receptor subfamily 1, group H, member 3
Gene Symbol
Nr1h3
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:MGI C nucleus
GO:0003677 IDA:MGI F DNA binding
GO:0004879 IDA:MGI F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0043565 IEA:InterPro F sequence-specific DNA binding
GO:0003700 IDA:MGI F sequence-specific DNA binding transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0044255 IDA:MGI P cellular lipid metabolic process
GO:0030522 IDA:GOC P intracellular receptor signaling pathway
GO:0045892 IMP:MGI P negative regulation of transcription, DNA-templated
GO:0006355 IDA:MGI P regulation of transcription, DNA-templated

Domain Information

InterPro Annotations

Accession Description
IPR023257 Liver X receptor
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
nuclear receptor subfamily 1, group H, member 3
Protein Entry
NR1H3_MOUSE
UniProt ID
Q91X41
Species
Mouse

Comments

Comment Type Description
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP000296 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
110625616 RefSeq NP_038867 445 oxysterols receptor LXR-alpha

Identical Sequences to LMP000296 proteins

Reference Database Accession Length Protein Name
GI:110625616 GenBank AEP73954.1 445 Sequence 4 from patent US 8013001
GI:110625616 RefSeq NP_001171201.1 445 oxysterols receptor LXR-alpha [Mus musculus]
GI:110625616 RefSeq XP_006499229.1 445 PREDICTED: oxysterols receptor LXR-alpha isoform X1 [Mus musculus]
GI:110625616 RefSeq XP_006499230.1 445 PREDICTED: oxysterols receptor LXR-alpha isoform X2 [Mus musculus]
GI:110625616 RefSeq XP_006499231.1 445 PREDICTED: oxysterols receptor LXR-alpha isoform X3 [Mus musculus]
GI:110625616 SwissProt Q9Z0Y9.3 445 RecName: Full=Oxysterols receptor LXR-alpha; AltName: Full=Liver X receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group H member 3 [Mus musculus]

Related Sequences to LMP000296 proteins

Reference Database Accession Length Protein Name
GI:110625616 EMBL CAB51923.1 445 nuclear oxysterol receptor LXR-alpha (LXR-alpha) [Mus musculus]
GI:110625616 EMBL CAB51952.1 445 nuclear oxysterol receptor LXR-alpha (LXR-alpha) [Mus musculus]
GI:110625616 GenBank EDL27546.1 452 nuclear receptor subfamily 1, group H, member 3, isoform CRA_c, partial [Mus musculus]
GI:110625616 GenBank EDL79513.1 445 nuclear receptor subfamily 1, group H, member 3, isoform CRA_a [Rattus norvegicus]
GI:110625616 GenBank EDL79514.1 445 nuclear receptor subfamily 1, group H, member 3, isoform CRA_a [Rattus norvegicus]
GI:110625616 RefSeq NP_113815.2 445 oxysterols receptor LXR-alpha [Rattus norvegicus]