Gene/Proteome Database (LMPD)

LMPD ID
LMP000342
Gene ID
Species
Mus musculus (Mouse)
Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
Gene Symbol
Synonyms
1810041M08Rik
Alternate Names
ATP synthase F(0) complex subunit C2, mitochondrial; ATPase protein 9; ATPase subunit c; ATP synthase proteolipid P2; ATP synthase lipid-binding protein, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2
Chromosome
15
Map Location
15 F3|15

Proteins

ATP synthase F(0) complex subunit C2, mitochondrial precursor
Refseq ID NP_080744
Protein GI 13385960
UniProt ID P56383
mRNA ID NM_026468
Length 146
RefSeq Status PROVISIONAL
MYACSKFVSTRSLIRSTSLRSTSQLLSRPLSAVELKRPQMPTDESLSSLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
transit_peptide: 1..71 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (P56383.2) calculated_mol_wt: 7886 peptide sequence: MYACSKFVSTRSLIRSTSLRSTSQLLSRPLSAVELKRPQMPTDESLSSLAVRRPLTSLIPSRSFQTSAISR mat_peptide: 72..146 product: ATP synthase F(0) complex subunit C2, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P56383.2) calculated_mol_wt: 7608 peptide sequence: DIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM

Gene Information

Entrez Gene ID
Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
Gene Symbol
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0045263 IEA:UniProtKB-KW C proton-transporting ATP synthase complex, coupling factor F(o)
GO:0015078 IEA:InterPro F hydrogen ion transmembrane transporter activity
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0015991 IEA:InterPro P ATP hydrolysis coupled proton transport
GO:0015986 IEA:InterPro P ATP synthesis coupled proton transport

KEGG Pathway Links

KEGG Pathway ID Description
mmu05010 Alzheimer's disease
mmu05016 Huntington's disease
mmu05012 Parkinson's disease

Domain Information

InterPro Annotations

Accession Description
IPR000454 ATPase, F0 complex, subunit C
IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site
IPR002379 V-ATPase proteolipid subunit C-like domain

UniProt Annotations

Entry Information

Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
Protein Entry
AT5G2_MOUSE
UniProt ID
Species
Mouse

Comments

Comment Type Description
Disease Note=This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Miscellaneous There are three genes which encode the mitochondrial ATP synthase proteolipid and they specify precursors with different import sequences but identical mature proteins. {ECO:0000305}.
Similarity Belongs to the ATPase C chain family. {ECO:0000305}.
Subcellular Location Mitochondrion membrane; Multi-pass membrane protein.
Subunit F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

Identical and Related Proteins

Unique RefSeq proteins for LMP000342 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
13385960 RefSeq NP_080744 146 ATP synthase F(0) complex subunit C2, mitochondrial precursor

Identical Sequences to LMP000342 proteins

Reference Database Accession Length Protein Name
GI:13385960 GenBank AAH81437.1 146 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 [Mus musculus]
GI:13385960 GenBank AAI06139.1 146 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 [Mus musculus]
GI:13385960 GenBank EDL01662.1 146 mCG118574 [Mus musculus]
GI:13385960 GenBank EDL03957.1 146 mCG17597 [Mus musculus]
GI:13385960 GenBank EDL24364.1 146 mCG113310 [Mus musculus]
GI:13385960 SwissProt P56383.2 146 RecName: Full=ATP synthase F(0) complex subunit C2, mitochondrial; AltName: Full=ATP synthase lipid-binding protein; AltName: Full=ATP synthase proteolipid P2; AltName: Full=ATPase protein 9; AltName: Full=ATPase subunit c; Flags: Precursor [Mus musculus]

Related Sequences to LMP000342 proteins

Reference Database Accession Length Protein Name
GI:13385960 GenBank AAI28727.1 141 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) [Rattus norvegicus]
GI:13385960 GenBank EDL04287.1 146 mCG19742 [Mus musculus]
GI:13385960 GenBank EDL86816.1 141 rCG50567, isoform CRA_a [Rattus norvegicus]
GI:13385960 RefSeq NP_598240.1 141 ATP synthase F(0) complex subunit C2, mitochondrial precursor [Rattus norvegicus]
GI:13385960 RefSeq XP_006521364.1 190 PREDICTED: ATP synthase F(0) complex subunit C2, mitochondrial isoform X1 [Mus musculus]
GI:13385960 SwissProt Q06646.1 141 RecName: Full=ATP synthase F(0) complex subunit C2, mitochondrial; AltName: Full=ATP synthase lipid-binding protein; AltName: Full=ATP synthase proteolipid P2; AltName: Full=ATPase protein 9; AltName: Full=ATPase subunit c; Flags: Precursor [Rattus norvegicus]