Gene/Proteome Database (LMPD)

LMPD ID
LMP000675
Gene ID
18798
Species
Mus musculus (Mouse)
Gene Name
phospholipase C, beta 4
Gene Symbol
Plcb4
Synonyms
A930039J07Rik; AI854601; C230058B11Rik
Chromosome
2
Map Location
2 F3|2 66.64 cM

Proteins

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4
Refseq ID NP_038857
Protein GI 29293803
UniProt ID Q91UZ1
mRNA ID NM_013829
Length 1175
RefSeq Status PROVISIONAL
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRQAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPASILEDDNEEEIESADQEEEAHPEYKFGNELSADDYSHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEIKKETEIKIQTLTTDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV

Gene Information

Entrez Gene ID
18798
Gene Name
phospholipase C, beta 4
Gene Symbol
Plcb4
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030425 IDA:MGI C dendrite
GO:0005634 IDA:MGI C nucleus
GO:0014069 IDA:MGI C postsynaptic density
GO:0005790 IDA:MGI C smooth endoplasmic reticulum
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR016280 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
IPR009535 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, conserved site
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, beta 4
Protein Entry
Q91UZ1_MOUSE
UniProt ID
Q91UZ1
Species
Mouse

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP000675 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
29293803 RefSeq NP_038857 1175 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4

Identical Sequences to LMP000675 proteins

Reference Database Accession Length Protein Name
GI:29293803 GenBank AAK56099.1 1175 phospholipase C beta 4 [Mus musculus]
GI:29293803 GenBank AAK56100.1 1175 phospholipase C beta 4 [Mus musculus]
GI:29293803 GenBank AAX90610.1 1175 Plcb4 [Mus musculus]
GI:29293803 GenBank AAI29884.1 1175 Phospholipase C, beta 4 [Mus musculus]
GI:29293803 RefSeq XP_006499007.1 1175 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 isoform X9 [Mus musculus]

Related Sequences to LMP000675 proteins

Reference Database Accession Length Protein Name
GI:29293803 GenBank EDL80293.1 1175 rCG26434, isoform CRA_b [Rattus norvegicus]
GI:29293803 GenBank EDL80296.1 1175 rCG26434, isoform CRA_b [Rattus norvegicus]
GI:29293803 RefSeq XP_006235156.1 1175 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4 [Rattus norvegicus]
GI:29293803 RefSeq XP_006499005.1 1187 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 isoform X7 [Mus musculus]
GI:29293803 RefSeq XP_006499006.1 1176 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 isoform X8 [Mus musculus]
GI:29293803 RefSeq XP_008760473.1 1175 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4 [Rattus norvegicus]