Gene/Proteome Database (LMPD)
Proteins
prostaglandin D2 receptor | |
---|---|
Refseq ID | NP_032988 |
Protein GI | 225543126 |
UniProt ID | P70263 |
mRNA ID | NM_008962 |
Length | 357 |
RefSeq Status | VALIDATED |
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL |
Gene Information
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
GO:0005886 | IDA:MGI | C | plasma membrane |
GO:0004956 | IDA:MGI | F | prostaglandin D receptor activity |
GO:0001785 | IDA:MGI | F | prostaglandin J receptor activity |
GO:0046085 | IMP:MGI | P | adenosine metabolic process |
GO:0071799 | IMP:MGI | P | cellular response to prostaglandin D stimulus |
GO:0006954 | IMP:MGI | P | inflammatory response |
GO:0030238 | IMP:MGI | P | male sex determination |
GO:0030431 | IMP:MGI | P | sleep |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
Comment Type | Description |
---|---|
Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). {ECO:0000250}. |
Similarity | Belongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}. |
Subcellular Location | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Most abundantly expressed in the ileum, followed by lung, stomach and uterus. |
Identical and Related Proteins
Unique RefSeq proteins for LMP000759 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
225543126 | RefSeq | NP_032988 | 357 | prostaglandin D2 receptor |
Identical Sequences to LMP000759 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:225543126 | GenBank | AAI32298.1 | 357 | Prostaglandin D receptor [Mus musculus] |
GI:225543126 | GenBank | ABP08275.1 | 357 | Sequence 17 from patent US 7183062 |
GI:225543126 | GenBank | EDL20681.1 | 357 | prostaglandin D receptor [Mus musculus] |
GI:225543126 | GenBank | ACN08921.1 | 357 | Sequence 17 from patent US 7488799 |
GI:225543126 | GenBank | ADL99487.1 | 357 | Sequence 17 from patent US 7723074 |
GI:225543126 | SwissProt | P70263.1 | 357 | RecName: Full=Prostaglandin D2 receptor; Short=PGD receptor; Short=PGD2 receptor; AltName: Full=Prostanoid DP receptor [Mus musculus] |
Related Sequences to LMP000759 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:225543126 | DBBJ | BAC27895.1 | 357 | unnamed protein product [Mus musculus] |
GI:225543126 | GenBank | ABP08274.1 | 357 | Sequence 16 from patent US 7183062 |
GI:225543126 | GenBank | ADL99486.1 | 357 | Sequence 16 from patent US 7723074 |
GI:225543126 | GenBank | AFL01478.1 | 357 | Sequence 2 from patent US 8165517 |
GI:225543126 | RefSeq | NP_001128636.1 | 357 | prostaglandin D2 receptor [Rattus norvegicus] |
GI:225543126 | SwissProt | Q9R261.1 | 357 | RecName: Full=Prostaglandin D2 receptor; Short=PGD receptor; Short=PGD2 receptor; AltName: Full=Prostanoid DP receptor [Rattus norvegicus] |