Gene/Proteome Database (LMPD)

LMPD ID
LMP000839
Gene ID
641371
Species
Homo sapiens (Human)
Gene Name
acyl-CoA thioesterase 1
Gene Symbol
ACOT1
Synonyms
ACH2; CTE-1; LACH2
Chromosome
14
Map Location
14q24.3

Proteins

acyl-coenzyme A thioesterase 1
Refseq ID NP_001032238
Protein GI 81230485
UniProt ID Q86TX2
mRNA ID NM_001037161
Length 421
RefSeq Status VALIDATED
MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV

Gene Information

Entrez Gene ID
641371
Gene Name
acyl-CoA thioesterase 1
Gene Symbol
ACOT1
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016790 IEA:InterPro F thiolester hydrolase activity
GO:0006637 IEA:InterPro P acyl-CoA metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
hsa01040 Biosynthesis of unsaturated fatty acids
hsa00062 Fatty acid elongation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5996 oleate biosynthesis II (animals)
PWY-5972 stearate biosynthesis I (animals)

Domain Information

InterPro Annotations

Accession Description
IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
IPR016662 Acyl-CoA thioesterase, long chain
IPR029058 Alpha/Beta hydrolase fold
IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal

UniProt Annotations

Entry Information

Gene Name
acyl-CoA thioesterase 1
Protein Entry
ACOT1_HUMAN
UniProt ID
Q86TX2
Species
Human

Identical and Related Proteins

Unique RefSeq proteins for LMP000839 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
81230485 RefSeq NP_001032238 421 acyl-coenzyme A thioesterase 1

Identical Sequences to LMP000839 proteins

Reference Database Accession Length Protein Name
GI:81230485 GenBank AAI27749.1 421 Acyl-CoA thioesterase 1 [Homo sapiens]
GI:81230485 GenBank AAI32890.1 421 Acyl-CoA thioesterase 1 [Homo sapiens]
GI:81230485 GenBank AAI32892.1 421 Acyl-CoA thioesterase 1 [Homo sapiens]
GI:81230485 GenBank AAI43043.1 421 Acyl-CoA thioesterase 1 [Homo sapiens]
GI:81230485 GenBank ADU87641.1 421 epididymis secretory sperm binding protein Li 188n [Homo sapiens]
GI:81230485 GenBank AIC53893.1 421 ACOT1, partial [synthetic construct]

Related Sequences to LMP000839 proteins

Reference Database Accession Length Protein Name
GI:81230485 DBBJ BAG62528.1 421 unnamed protein product [Homo sapiens]
GI:81230485 GenBank AAI27748.1 421 Acyl-CoA thioesterase 1 [Homo sapiens]
GI:81230485 GenBank JAA18936.1 483 acyl-CoA thioesterase 2 [Pan troglodytes]
GI:81230485 GenBank JAA31528.1 483 acyl-CoA thioesterase 2 [Pan troglodytes]
GI:81230485 GenBank JAA41922.1 483 acyl-CoA thioesterase 2 [Pan troglodytes]
GI:81230485 RefSeq XP_510048.2 483 PREDICTED: acyl-coenzyme A thioesterase 2, mitochondrial [Pan troglodytes]