Gene/Proteome Database (LMPD)

LMPD ID
LMP000881
Gene ID
70568
Species
Mus musculus (Mouse)
Gene Name
copine III
Gene Symbol
Cpne3
Synonyms
5430428M23Rik; 5730450C07Rik; C85108; CPN3
Alternate Names
copine-3
Chromosome
4
Map Location
4 A3|4
Summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
Orthologs
View orthologs and multiple alignments for Cpne3

Proteins

copine-3
Refseq ID NP_082045
Protein GI 25141335
UniProt ID Q8BT60
mRNA ID NM_027769
Length 533
RefSeq Status REVIEWED
MAAQCVTKVELNVSCNNLLDADVTSKSDPLCVLFLNTSGHQWYEVERTERIKNSLNPKFSKTFVIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGECEVTLGQIVSSKKLTRPLVLKNGKPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGHWLMVHRTEVIKNNLNPMWKPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEYECINEKKRQKKKSYKNSGVISVKHCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPSSPDSLHYISPNGVNEYLTAIWSVGLVIQDYDADKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRTCLPQIRLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNAAKLPMSIIIVGVGGADFSAMEFLDGDGGSLRAPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPAVK

Gene Information

Entrez Gene ID
70568
Gene Name
copine III
Gene Symbol
Cpne3
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 ISS:UniProtKB C cytosol
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0044822 IEA:Ensembl F poly(A) RNA binding
GO:0004674 ISS:UniProtKB F protein serine/threonine kinase activity

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR010734 Copine
IPR002035 von Willebrand factor, type A

UniProt Annotations

Entry Information

Gene Name
copine III
Protein Entry
CPNE3_MOUSE
UniProt ID
Q8BT60
Species
Mouse

Comments

Comment Type Description
Function May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity). {ECO:0000250}.
Sequence Caution Sequence=BAD90244.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the copine family. {ECO:0000305}.
Similarity Contains 1 VWFA domain. {ECO:0000305}.
Similarity Contains 2 C2 domains. {ECO:0000255|PROSITE- ProRule:PRU00041}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000881 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
25141335 RefSeq NP_082045 533 copine-3

Identical Sequences to LMP000881 proteins

Reference Database Accession Length Protein Name
GI:25141335 GenBank AAH90632.1 533 Copine III [Mus musculus]
GI:25141335 GenBank EDL05581.1 533 copine III, isoform CRA_b [Mus musculus]
GI:25141335 SwissProt Q8BT60.2 533 RecName: Full=Copine-3; AltName: Full=Copine III [Mus musculus]

Related Sequences to LMP000881 proteins

Reference Database Accession Length Protein Name
GI:25141335 DBBJ BAD90244.1 560 mKIAA0636 protein, partial [Mus musculus]
GI:25141335 DBBJ BAE27079.1 533 unnamed protein product [Mus musculus]
GI:25141335 EMBL CAN89608.1 533 copine 3 protein [Rattus norvegicus]
GI:25141335 GenBank EDL98496.1 533 copine III (predicted), isoform CRA_b [Rattus norvegicus]
GI:25141335 RefSeq XP_005362400.1 533 PREDICTED: copine-3 [Microtus ochrogaster]
GI:25141335 RefSeq XP_006237994.1 533 PREDICTED: copine-3 isoform X1 [Rattus norvegicus]