Gene/Proteome Database (LMPD)

LMPD ID
LMP000887
Gene ID
70796
Species
Mus musculus (Mouse)
Gene Name
zinc finger, DHHC domain containing 1
Gene Symbol
Zdhhc1
Synonyms
4432412D04Rik
Alternate Names
probable palmitoyltransferase ZDHHC1; DHHC-1; zinc finger DHHC domain-containing protein 1
Chromosome
8
Map Location
8 D3|8
EC Number
2.3.1.225

Proteins

probable palmitoyltransferase ZDHHC1
Refseq ID NP_780369
Protein GI 30424758
UniProt ID Q8R0N9
mRNA ID NM_175160
Length 484
RefSeq Status PROVISIONAL
MNICNKPSNKTAPEKSVWTAPSQDSGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPAQEAKETHKELESCPRKVRSIQEMEFYMRTFSHVRPEPSGQARTAALNANPSQFLATQGQVEPPLPSSSDTLALPPRIQPQKKRKRRVYRLPRSGVLDRELPLPRLRETGTPSRRSSSSSDSTSASPVHAGGSAGAYYSASAESMEEIPVAQTRLGSAALGAPGARGRESGLALQARSPAVFVSPSSGEPGTPGGGDGLP

Gene Information

Entrez Gene ID
70796
Gene Name
zinc finger, DHHC domain containing 1
Gene Symbol
Zdhhc1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:Ensembl C endoplasmic reticulum
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016409 IDA:MGI F palmitoyltransferase activity
GO:0019706 IEA:UniProtKB-EC F protein-cysteine S-palmitoyltransferase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0018345 IDA:MGI P protein palmitoylation

Domain Information

InterPro Annotations

Accession Description
IPR001594 Zinc finger, DHHC-type, palmitoyltransferase

UniProt Annotations

Entry Information

Gene Name
zinc finger, DHHC domain containing 1
Protein Entry
ZDHC1_MOUSE
UniProt ID
Q8R0N9
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
Domain The DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}.
Similarity Belongs to the DHHC palmitoyltransferase family. {ECO:0000305}.
Similarity Contains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed at high levels in fetal lung and heart. Expressed at lower levels in fetal liver and brain. Also detected in adult islet cells of pancreas, Leydig cells of testis, retina and molecular layer of cerebellum. {ECO:0000269|PubMed:10395086}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000887 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30424758 RefSeq NP_780369 484 probable palmitoyltransferase ZDHHC1

Identical Sequences to LMP000887 proteins

Reference Database Accession Length Protein Name
GI:30424758 DBBJ BAC30059.1 484 unnamed protein product [Mus musculus]
GI:30424758 GenBank AAI19379.1 484 Zinc finger, DHHC domain containing 1 [Mus musculus]
GI:30424758 GenBank AAH26570.2 484 Zinc finger, DHHC domain containing 1 [Mus musculus]
GI:30424758 RefSeq XP_006531420.1 484 PREDICTED: probable palmitoyltransferase ZDHHC1 isoform X5 [Mus musculus]
GI:30424758 SwissProt Q8R0N9.2 484 RecName: Full=Probable palmitoyltransferase ZDHHC1; AltName: Full=Zinc finger DHHC domain-containing protein 1; Short=DHHC-1 [Mus musculus]

Related Sequences to LMP000887 proteins

Reference Database Accession Length Protein Name
GI:30424758 GenBank EDL11283.1 518 zinc finger, DHHC domain containing 1, isoform CRA_a, partial [Mus musculus]
GI:30424758 GenBank AAI44879.1 479 Zdhhc1 protein [Mus musculus]
GI:30424758 RefSeq XP_006531416.1 493 PREDICTED: probable palmitoyltransferase ZDHHC1 isoform X1 [Mus musculus]
GI:30424758 RefSeq XP_006531417.1 493 PREDICTED: probable palmitoyltransferase ZDHHC1 isoform X2 [Mus musculus]
GI:30424758 RefSeq XP_006531418.1 493 PREDICTED: probable palmitoyltransferase ZDHHC1 isoform X3 [Mus musculus]
GI:30424758 RefSeq XP_006531421.1 479 PREDICTED: probable palmitoyltransferase ZDHHC1 isoform X6 [Mus musculus]