Gene/Proteome Database (LMPD)

LMPD ID
LMP000898
Gene ID
110460
Species
Mus musculus (Mouse)
Gene Name
acetyl-Coenzyme A acetyltransferase 2
Gene Symbol
Acat2
Synonyms
AW742799; Tcp-1x; Tcp1-rs1
Alternate Names
acetyl-CoA acetyltransferase, cytosolic; cytosolic acetoacetyl-CoA thiolase; t-complex protein 1, related sequence 1
Chromosome
17
Map Location
17 A2-A3|17 8.73 cM
EC Number
2.3.1.9

Proteins

acetyl-CoA acetyltransferase, cytosolic
Refseq ID NP_033364
Protein GI 148747461
UniProt ID Q8CAY6
mRNA ID NM_009338
Length 397
RefSeq Status PROVISIONAL
MNAGSDPVVIVSAARTAIGSFNGALSTVPVHEMGTTVIKEVLQRAKVAPEEVSEVIFGHVLTAGCGQNPTRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHLTHLRTGVRMGEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVLSQNRAEHAQKAGHFDKEIVPVLVSSRKGLTEVKIDEFPRHGSNLEAMGKLKPYFLTDGTGTVTPANASGMNDGAAAVVLMKKTEAERRMLKPLARIVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDLFEINEAFAAVSAAIAKELGLNPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGGTRGVAALCIGGGMGVAMCVQRG

Gene Information

Entrez Gene ID
110460
Gene Name
acetyl-Coenzyme A acetyltransferase 2
Gene Symbol
Acat2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:MGI C mitochondrion
GO:0003985 IEA:UniProtKB-EC F acetyl-CoA C-acetyltransferase activity

KEGG Pathway Links

KEGG Pathway ID Description
mmu01200 Carbon metabolism
mmu04975 Fat digestion and absorption
mmu00900 Terpenoid backbone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR002155 Thiolase
IPR020617 Thiolase, C-terminal
IPR020616 Thiolase, N-terminal
IPR020610 Thiolase, active site
IPR020613 Thiolase, conserved site
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup

UniProt Annotations

Entry Information

Gene Name
acetyl-Coenzyme A acetyltransferase 2
Protein Entry
THIC_MOUSE
UniProt ID
Q8CAY6
Species
Mouse

Comments

Comment Type Description
Catalytic Activity 2 acetyl-CoA = CoA + acetoacetyl-CoA. {ECO:0000255|PROSITE-ProRule:PRU10020}.
Sequence Caution Sequence=BAB28763.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the thiolase family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250}.
Subunit Homotetramer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000898 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
148747461 RefSeq NP_033364 397 acetyl-CoA acetyltransferase, cytosolic

Identical Sequences to LMP000898 proteins

Reference Database Accession Length Protein Name
GI:148747461 DBBJ BAE39040.1 397 unnamed protein product [Mus musculus]
GI:148747461 DBBJ BAE39358.1 397 unnamed protein product [Mus musculus]
GI:148747461 GenBank AAH04823.2 397 Acetyl-Coenzyme A acetyltransferase 2 [Mus musculus]
GI:148747461 SwissProt Q8CAY6.2 397 RecName: Full=Acetyl-CoA acetyltransferase, cytosolic; AltName: Full=Cytosolic acetoacetyl-CoA thiolase [Mus musculus]

Related Sequences to LMP000898 proteins

Reference Database Accession Length Protein Name
GI:148747461 DBBJ BAC29776.1 397 unnamed protein product [Mus musculus]
GI:148747461 DBBJ BAE28878.1 397 unnamed protein product [Mus musculus]
GI:148747461 DBBJ BAE25582.1 397 unnamed protein product [Mus musculus]
GI:148747461 GenBank AAH12496.2 397 Acetyl-Coenzyme A acetyltransferase 2 [Mus musculus]
GI:148747461 GenBank EDL02034.1 397 mCG16687, isoform CRA_f [Mus musculus]
GI:148747461 RefSeq NP_694791.2 397 acetyl-Coenzyme A acetyltransferase 3 [Mus musculus]