Gene/Proteome Database (LMPD)

LMPD ID
LMP000926
Gene ID
12896
Species
Mus musculus (Mouse)
Gene Name
carnitine palmitoyltransferase 2
Gene Symbol
Cpt2
Synonyms
AI323697; CPTII
Alternate Names
carnitine O-palmitoyltransferase 2, mitochondrial; CPT II; carnitine palmitoyltransferase II
Chromosome
4
Map Location
4 C7|4 50.18 cM
EC Number
2.3.1.21

Proteins

carnitine O-palmitoyltransferase 2, mitochondrial precursor
Refseq ID NP_034079
Protein GI 162138915
UniProt ID P52825
mRNA ID NM_009949
Length 658
RefSeq Status VALIDATED
MMPRLLLRDWPRCPSLVLGAPSRPLSAVSGPAEYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLRAGLLEPEVFHLNPARSDTDAFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPKPSRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILSDSSPVPEFPLAYLTSENRDVWAELRQKLIHGGNEETLRKVDSAVFCLCLDDFPMKDLVHLSHTMLHGDGTNRWFDKSFNLIVAKDGTAAVHFEHAWGDGVAVLRFFNEVFRDSTQTPAIAPQSQPAATDSSVSVQKLSFKLSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVREPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSGRNAREFLHCVQKCLEDMFDALEGKAIKT
transit_peptide: 1..25 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (P52825.2) calculated_mol_wt: 2876 peptide sequence: MMPRLLLRDWPRCPSLVLGAPSRPL mat_peptide: 26..658 product: Carnitine O-palmitoyltransferase 2, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P52825.2) calculated_mol_wt: 71123 peptide sequence: SAVSGPAEYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLRAGLLEPEVFHLNPARSDTDAFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPKPSRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILSDSSPVPEFPLAYLTSENRDVWAELRQKLIHGGNEETLRKVDSAVFCLCLDDFPMKDLVHLSHTMLHGDGTNRWFDKSFNLIVAKDGTAAVHFEHAWGDGVAVLRFFNEVFRDSTQTPAIAPQSQPAATDSSVSVQKLSFKLSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVREPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSGRNAREFLHCVQKCLEDMFDALEGKAIKT

Gene Information

Entrez Gene ID
12896
Gene Name
carnitine palmitoyltransferase 2
Gene Symbol
Cpt2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0005739 IDA:MGI C mitochondrion
GO:0005730 IEA:Ensembl C nucleolus
GO:0004095 IEA:UniProtKB-EC F carnitine O-palmitoyltransferase activity
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process
GO:0006810 IEA:UniProtKB-KW P transport

KEGG Pathway Links

KEGG Pathway ID Description
mmu00071 Fatty acid degradation
mmu03320 PPAR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR000542 Acyltransferase ChoActase/COT/CPT

UniProt Annotations

Entry Information

Gene Name
carnitine palmitoyltransferase 2
Protein Entry
CPT2_MOUSE
UniProt ID
P52825
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Palmitoyl-CoA + L-carnitine = CoA + L- palmitoylcarnitine.
Similarity Belongs to the carnitine/choline acetyltransferase family. {ECO:0000305}.
Subcellular Location Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP000926 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
162138915 RefSeq NP_034079 658 carnitine O-palmitoyltransferase 2, mitochondrial precursor

Identical Sequences to LMP000926 proteins

Reference Database Accession Length Protein Name
GI:162138915 DBBJ BAE40828.1 658 unnamed protein product [Mus musculus]
GI:162138915 GenBank EDL30761.1 658 carnitine palmitoyltransferase 2 [Mus musculus]
GI:162138915 GenBank AAI45860.1 658 Carnitine palmitoyltransferase 2 [Mus musculus]
GI:162138915 GenBank AAI38515.1 658 Carnitine palmitoyltransferase 2 [Mus musculus]
GI:162138915 SwissProt P52825.2 658 RecName: Full=Carnitine O-palmitoyltransferase 2, mitochondrial; AltName: Full=Carnitine palmitoyltransferase II; Short=CPT II; Flags: Precursor [Mus musculus]

Related Sequences to LMP000926 proteins

Reference Database Accession Length Protein Name
GI:162138915 DBBJ BAE25892.1 658 unnamed protein product [Mus musculus]
GI:162138915 EMBL CBN63527.1 658 unnamed protein product [Mus musculus]
GI:162138915 EMBL CBN60635.1 658 unnamed protein product [Mus musculus]
GI:162138915 EMBL CBN65244.1 658 unnamed protein product [Mus musculus]
GI:162138915 GenBank AAA18921.1 658 carnitine palmitoyltransferase II [Mus musculus]
GI:162138915 GenBank AAA18922.1 658 carnitine palmitoyltransferase II [Mus musculus]