Gene/Proteome Database (LMPD)

LMPD ID
LMP000934
Gene ID
20186
Species
Mus musculus (Mouse)
Gene Name
nuclear receptor subfamily 1, group H, member 4
Gene Symbol
Nr1h4
Synonyms
AI957360; Fxr; HRR1; RIP14; Rxrip14
Chromosome
10
Map Location
10 C2|10 44.98 cM

Proteins

bile acid receptor isoform 1
Refseq ID NP_001157172
Protein GI 254911067
UniProt ID Q60641
mRNA ID NM_001163700
Length 488
RefSeq Status VALIDATED
MVMQFQGLENPIQISLHHSHRLSGFVPEGMSVKPAKGMLTEHAAGPLGQNLDLESYSPYNNVPFPQVQPQISSSSYYSNLGFYPQQPEDWYSPGIYELRRMPAETGYQGETEVSEMPVTKKPRMAAASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTANEDDSEGRDLRQVTSTTKFCREKTELTADQQTLLDYIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPAGHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKMYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
bile acid receptor isoform 2
Refseq ID NP_001156976
Protein GI 254911039
UniProt ID D3YTT2
mRNA ID NM_001163504
Length 474
RefSeq Status VALIDATED
MNLIGHSHLQATDEFSLSESLFGMLTEHAAGPLGQNLDLESYSPYNNVPFPQVQPQISSSSYYSNLGFYPQQPEDWYSPGIYELRRMPAETGYQGETEVSEMPVTKKPRMAAASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTANEDDSEGRDLRQVTSTTKFCREKTELTADQQTLLDYIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPAGHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKMYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
bile acid receptor isoform 3
Refseq ID NP_033134
Protein GI 254911035
UniProt ID Q3V1T8
mRNA ID NM_009108
Length 484
RefSeq Status VALIDATED
MVMQFQGLENPIQISLHHSHRLSGFVPEGMSVKPAKGMLTEHAAGPLGQNLDLESYSPYNNVPFPQVQPQISSSSYYSNLGFYPQQPEDWYSPGIYELRRMPAETGYQGETEVSEMPVTKKPRMAAASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTANEDDSEGRDLRQVTSTTKFCREKTELTADQQTLLDYIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATSHVQILVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPAGHADLLEERIRKSGISDEYITPMFSFYKSVGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKMYQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ

Gene Information

Entrez Gene ID
20186
Gene Name
nuclear receptor subfamily 1, group H, member 4
Gene Symbol
Nr1h4
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0046965 IDA:MGI F retinoid X receptor binding
GO:0043565 IEA:InterPro F sequence-specific DNA binding
GO:0003700 IGI:MGI F sequence-specific DNA binding transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0004887 IEA:InterPro F thyroid hormone receptor activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0008206 IMP:MGI P bile acid metabolic process
GO:0006357 IGI:MGI P regulation of transcription from RNA polymerase II promoter

Domain Information

InterPro Annotations

Accession Description
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR001728 Thyroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
nuclear receptor subfamily 1, group H, member 4
Protein Entry
NR1H4_MOUSE
UniProt ID
Q60641
Species
Mouse

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP000934 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
254911067 RefSeq NP_001157172 488 bile acid receptor isoform 1
254911039 RefSeq NP_001156976 474 bile acid receptor isoform 2
254911035 RefSeq NP_033134 484 bile acid receptor isoform 3

Identical Sequences to LMP000934 proteins

Reference Database Accession Length Protein Name
GI:254911035 DBBJ BAE21061.1 484 unnamed protein product [Mus musculus]
GI:254911039 RefSeq XP_006513454.1 474 PREDICTED: bile acid receptor isoform X1 [Mus musculus]
GI:254911039 RefSeq XP_006513455.1 474 PREDICTED: bile acid receptor isoform X2 [Mus musculus]
GI:254911067 SwissProt Q60641.3 488 RecName: Full=Bile acid receptor; AltName: Full=Farnesoid X-activated receptor; AltName: Full=Farnesol receptor HRR-1; AltName: Full=Nuclear receptor subfamily 1 group H member 4; AltName: Full=Retinoid X receptor-interacting protein 14; Short=RXR-interacting protein 14 [Mus musculus]

Related Sequences to LMP000934 proteins

Reference Database Accession Length Protein Name
GI:254911067 DBBJ BAE21061.1 484 unnamed protein product [Mus musculus]
GI:254911035 GenBank AAC53066.1 484 retinoid X receptor interacting protein No.6 [Mus musculus]
GI:254911067 GenBank AAC53066.1 484 retinoid X receptor interacting protein No.6 [Mus musculus]
GI:254911035 GenBank AAH15261.1 484 Nuclear receptor subfamily 1, group H, member 4 [Mus musculus]
GI:254911067 GenBank AAH15261.1 484 Nuclear receptor subfamily 1, group H, member 4 [Mus musculus]
GI:254911035 GenBank ABA07288.1 484 Sequence 2 from patent US 6906057
GI:254911035 GenBank ABJ48463.1 484 Sequence 1 from patent US 7115711
GI:254911067 GenBank ABJ48463.1 484 Sequence 1 from patent US 7115711
GI:254911039 GenBank ABJ48464.1 451 Sequence 2 from patent US 7115711
GI:254911067 GenBank EDL21502.1 510 nuclear receptor subfamily 1, group H, member 4, isoform CRA_c [Mus musculus]
GI:254911035 GenBank EDL21502.1 510 nuclear receptor subfamily 1, group H, member 4, isoform CRA_c [Mus musculus]
GI:254911039 GenBank EDL21502.1 510 nuclear receptor subfamily 1, group H, member 4, isoform CRA_c [Mus musculus]
GI:254911067 RefSeq NP_033134.2 484 bile acid receptor isoform 3 [Mus musculus]
GI:254911039 RefSeq NP_001157172.1 488 bile acid receptor isoform 1 [Mus musculus]
GI:254911039 RefSeq XP_006513456.1 470 PREDICTED: bile acid receptor isoform X3 [Mus musculus]
GI:254911039 RefSeq XP_008763484.1 473 PREDICTED: bile acid receptor isoform X3 [Rattus norvegicus]
GI:254911035 SwissProt Q60641.3 488 RecName: Full=Bile acid receptor; AltName: Full=Farnesoid X-activated receptor; AltName: Full=Farnesol receptor HRR-1; AltName: Full=Nuclear receptor subfamily 1 group H member 4; AltName: Full=Retinoid X receptor-interacting protein 14; Short=RXR-interacting protein 14 [Mus musculus]
GI:254911039 SwissProt Q60641.3 488 RecName: Full=Bile acid receptor; AltName: Full=Farnesoid X-activated receptor; AltName: Full=Farnesol receptor HRR-1; AltName: Full=Nuclear receptor subfamily 1 group H member 4; AltName: Full=Retinoid X receptor-interacting protein 14; Short=RXR-interacting protein 14 [Mus musculus]