Gene/Proteome Database (LMPD)

LMPD ID
LMP000942
Gene ID
14667
Species
Mus musculus (Mouse)
Gene Name
GM2 ganglioside activator protein
Gene Symbol
Gm2a
Synonyms
AA408702; AW215435; GM2-AP; SAP-3
Chromosome
11
Map Location
11 B1.3|11 32.13 cM

Proteins

ganglioside GM2 activator precursor
Refseq ID NP_034429
Protein GI 6806917
UniProt ID Q5F1Z8
mRNA ID NM_010299
Length 193
RefSeq Status VALIDATED
MHRLPLLLLLGLLLAGSVAPARLVPKRLSQLGGFSWDNCDEGKDPAVIKSLTIQPDPIVVPGDVVVSLEGKTSVPLTAPQKVELTVEKEVAGFWVKIPCVEQLGSCSYENICDLIDEYIPPGESCPEPLHTYGLPCHCPFKEGTYSLPTSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLGCIKIAASLKGR
sig_peptide: 1..20 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2098 peptide sequence: MHRLPLLLLLGLLLAGSVAP mat_peptide: 21..193 product: Ganglioside GM2 activator experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q60648.2) calculated_mol_wt: 18745 peptide sequence: ARLVPKRLSQLGGFSWDNCDEGKDPAVIKSLTIQPDPIVVPGDVVVSLEGKTSVPLTAPQKVELTVEKEVAGFWVKIPCVEQLGSCSYENICDLIDEYIPPGESCPEPLHTYGLPCHCPFKEGTYSLPTSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLGCIKIAASLKGR

Gene Information

Entrez Gene ID
14667
Gene Name
GM2 ganglioside activator protein
Gene Symbol
Gm2a
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0045179 IEA:Ensembl C apical cortex
GO:0009898 IEA:Ensembl C cytoplasmic side of plasma membrane
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005889 IEA:Ensembl C hydrogen:potassium-exchanging ATPase complex
GO:0005764 IEA:Ensembl C lysosome
GO:0005739 IDA:MGI C mitochondrion
GO:0032428 IEA:Ensembl F beta-N-acetylgalactosaminidase activity
GO:0004563 IMP:MGI F beta-N-acetylhexosaminidase activity
GO:0008047 IDA:MGI F enzyme activator activity
GO:0005319 IEA:Ensembl F lipid transporter activity
GO:0016004 IEA:Ensembl F phospholipase activator activity
GO:0006689 IMP:MGI P ganglioside catabolic process
GO:0007611 IMP:MGI P learning or memory
GO:0019915 IMP:MGI P lipid storage
GO:0050877 IMP:MGI P neurological system process
GO:0050885 IMP:MGI P neuromuscular process controlling balance
GO:0009313 IMP:MGI P oligosaccharide catabolic process
GO:0051345 IEA:Ensembl P positive regulation of hydrolase activity

Domain Information

InterPro Annotations

Accession Description
IPR028996 Ganglioside GM2 activator
IPR003172 MD-2-related lipid-recognition domain

UniProt Annotations

Entry Information

Gene Name
GM2 ganglioside activator protein
Protein Entry
SAP3_MOUSE
UniProt ID
Q5F1Z8
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP000942 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6806917 RefSeq NP_034429 193 ganglioside GM2 activator precursor

Identical Sequences to LMP000942 proteins

Reference Database Accession Length Protein Name
GI:6806917 DBBJ BAE31075.1 193 unnamed protein product [Mus musculus]
GI:6806917 EMBL CAJ18497.1 193 Gm2a [Mus musculus]
GI:6806917 GenBank AAB06275.1 193 GM2 activator protein [Mus musculus]
GI:6806917 GenBank AAH04651.1 193 GM2 ganglioside activator protein [Mus musculus]
GI:6806917 GenBank EDL33503.1 193 GM2 ganglioside activator protein [Mus musculus]
GI:6806917 SwissProt Q60648.2 193 RecName: Full=Ganglioside GM2 activator; AltName: Full=Cerebroside sulfate activator protein; AltName: Full=GM2-AP; AltName: Full=Sphingolipid activator protein 3; Short=SAP-3; Flags: Precursor [Mus musculus]

Related Sequences to LMP000942 proteins

Reference Database Accession Length Protein Name
GI:6806917 DBBJ BAC24018.1 199 GM2 activator protein [Rattus norvegicus]
GI:6806917 GenBank AAA21543.1 193 GM2 activator protein [Mus musculus]
GI:6806917 GenBank AAH72474.1 199 GM2 ganglioside activator [Rattus norvegicus]
GI:6806917 GenBank EDM04464.1 199 GM2 ganglioside activator protein [Rattus norvegicus]
GI:6806917 RefSeq NP_758838.2 199 ganglioside GM2 activator precursor [Rattus norvegicus]
GI:6806917 RefSeq XP_006984937.1 193 PREDICTED: ganglioside GM2 activator [Peromyscus maniculatus bairdii]