Gene/Proteome Database (LMPD)

LMPD ID
LMP000989
Gene ID
18781
Species
Mus musculus (Mouse)
Gene Name
phospholipase A2, group IIC
Gene Symbol
Pla2g2c
Synonyms
-
Chromosome
4
Map Location
4 D3|4 70.54 cM

Proteins

group IIC secretory phospholipase A2 precursor
Refseq ID NP_032894
Protein GI 225543511
UniProt ID P48076
mRNA ID NM_008868
Length 150
RefSeq Status VALIDATED
MKGIAIFLVFIFYWTTSTLSSFWQFQRMVKHVTGRSAFFSYYGYGCYCGLGGKGLPVDATDRCCWAHDCCYHKLKEYGCQPILNAYQFTIVNGTVTCGCTVASSCLCGQKACECDKQSVYCFKENLATYEKAFKQLFPTRPQCGRDKLQC
sig_peptide: 1..20 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2339 peptide sequence: MKGIAIFLVFIFYWTTSTLS mat_peptide: 21..150 product: Group IIC secretory phospholipase A2 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P48076.1) calculated_mol_wt: 14678 peptide sequence: SFWQFQRMVKHVTGRSAFFSYYGYGCYCGLGGKGLPVDATDRCCWAHDCCYHKLKEYGCQPILNAYQFTIVNGTVTCGCTVASSCLCGQKACECDKQSVYCFKENLATYEKAFKQLFPTRPQCGRDKLQC

Gene Information

Entrez Gene ID
18781
Gene Name
phospholipase A2, group IIC
Gene Symbol
Pla2g2c
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0005509 IEA:InterPro F calcium ion binding
GO:0047498 IEA:Ensembl F calcium-dependent phospholipase A2 activity
GO:0004623 ISO:MGI F phospholipase A2 activity
GO:0009395 ISO:MGI P phospholipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR001211 Phospholipase A2
IPR016090 Phospholipase A2 domain
IPR013090 Phospholipase A2, active site

UniProt Annotations

Entry Information

Gene Name
phospholipase A2, group IIC
Protein Entry
PA2GC_MOUSE
UniProt ID
P48076
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Phosphatidylcholine + H(2)O = 1- acylglycerophosphocholine + a carboxylate.
Cofactor Note=Binds 1 calcium ion per subunit. ;
Similarity Belongs to the phospholipase A2 family.
Subcellular Location Secreted .

Identical and Related Proteins

Unique RefSeq proteins for LMP000989 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
225543511 RefSeq NP_032894 150 group IIC secretory phospholipase A2 precursor

Identical Sequences to LMP000989 proteins

Reference Database Accession Length Protein Name
GI:225543511 GenBank ABK42326.1 150 PLA2-II-c [synthetic construct]
GI:225543511 GenBank EDL13275.1 150 phospholipase A2, group IIC [Mus musculus]

Related Sequences to LMP000989 proteins

Reference Database Accession Length Protein Name
GI:225543511 GenBank AAC52936.1 150 phospholipase A2 [Mus musculus]
GI:225543511 GenBank AAH29347.1 150 Phospholipase A2, group IIC [Mus musculus]
GI:225543511 GenBank AEU43293.1 150 Sequence 42 from patent US 8052970
GI:225543511 GenBank AEU43302.1 150 Sequence 51 from patent US 8052970
GI:225543511 SwissProt P48076.1 150 RecName: Full=Group IIC secretory phospholipase A2; Short=GIIC sPLA2; Short=sPLA2-IIC; AltName: Full=14 kDa phospholipase A2; AltName: Full=PLA2-8; AltName: Full=Phosphatidylcholine 2-acylhydrolase 2C; Flags: Precursor [Mus musculus]
GI:225543511 SwissProt P39878.2 150 RecName: Full=Group IIC secretory phospholipase A2; Short=GIIC sPLA2; Short=sPLA2-IIC; AltName: Full=14 kDa phospholipase A2; AltName: Full=PLA2-8; AltName: Full=Phosphatidylcholine 2-acylhydrolase 2C; Flags: Precursor [Rattus norvegicus]