Gene/Proteome Database (LMPD)

LMPD ID
LMP001210
Gene ID
3172
Species
Homo sapiens (Human)
Gene Name
hepatocyte nuclear factor 4, alpha
Gene Symbol
HNF4A
Synonyms
FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14
Chromosome
20
Map Location
20q13.12
Summary
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
Orthologs
View orthologs and multiple alignments for HNF4A

Proteins

hepatocyte nuclear factor 4-alpha isoform HNF4alpha1
Refseq ID NP_849180
Protein GI 31077207
UniProt ID F1D8S2
mRNA ID NM_178849
Length 464
RefSeq Status REVIEWED
MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha10
Refseq ID NP_001274111
Protein GI 385298694
UniProt ID P41235
mRNA ID NM_001287182
Length 467
RefSeq Status REVIEWED
MILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha11
Refseq ID NP_001274112
Protein GI 385298694
UniProt ID P41235
mRNA ID NM_001287183
Length 467
RefSeq Status REVIEWED
MILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha12
Refseq ID NP_001274113
Protein GI 385298694
UniProt ID P41235
mRNA ID NM_001287184
Length 467
RefSeq Status REVIEWED
MILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha2
Refseq ID NP_000448
Protein GI 31077205
UniProt ID P41235
mRNA ID NM_000457
Length 474
RefSeq Status REVIEWED
MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha3
Refseq ID NP_849181
Protein GI 31077209
UniProt ID P41235
mRNA ID NM_178850
Length 417
RefSeq Status REVIEWED
MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPGDRPHTVSSPLSSLASPLCRFGQVA
hepatocyte nuclear factor 4-alpha isoform HNF4alpha4
Refseq ID NP_001245284
Protein GI 385298694
UniProt ID P41235
mRNA ID NM_001258355
Length 467
RefSeq Status REVIEWED
MILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha7
Refseq ID NP_001025174
Protein GI 71725341
UniProt ID P41235
mRNA ID NM_001030003
Length 442
RefSeq Status REVIEWED
MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMSTPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha8
Refseq ID NP_787110
Protein GI 71725339
UniProt ID P41235
mRNA ID NM_175914
Length 452
RefSeq Status REVIEWED
MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
hepatocyte nuclear factor 4-alpha isoform HNF4alpha9
Refseq ID NP_001025175
Protein GI 71725336
UniProt ID P41235
mRNA ID NM_001030004
Length 395
RefSeq Status REVIEWED
MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPGDRPHTVSSPLSSLASPLCRFGQVA

Gene Information

Entrez Gene ID
3172
Gene Name
hepatocyte nuclear factor 4, alpha
Gene Symbol
HNF4A
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:BHF-UCL C cytoplasm
GO:0005654 TAS:Reactome C nucleoplasm
GO:0005634 IDA:BHF-UCL C nucleus
GO:0003677 IDA:BHF-UCL F DNA binding
GO:0001102 ISS:BHF-UCL F RNA polymerase II activating transcription factor binding
GO:0001077 ISS:BHF-UCL F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0000979 IEA:Ensembl F RNA polymerase II core promoter sequence-specific DNA binding
GO:0003705 IEA:Ensembl F RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005504 IDA:BHF-UCL F fatty acid binding
GO:0004879 IEA:InterPro F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0042803 IDA:BHF-UCL F protein homodimerization activity
GO:0005102 IDA:BHF-UCL F receptor binding
GO:0003700 IDA:BHF-UCL F sequence-specific DNA binding transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0044212 IDA:BHF-UCL F transcription regulatory region DNA binding
GO:0008270 IEA:InterPro F zinc ion binding
GO:0060395 IEA:Ensembl P SMAD protein signal transduction
GO:0007596 IDA:BHF-UCL P blood coagulation
GO:0031018 TAS:Reactome P endocrine pancreas development
GO:0010467 TAS:Reactome P gene expression
GO:0042593 ISS:BHF-UCL P glucose homeostasis
GO:0055088 IMP:BHF-UCL P lipid homeostasis
GO:0006629 IEA:Ensembl P lipid metabolic process
GO:0030308 IMP:BHF-UCL P negative regulation of cell growth
GO:0008285 IMP:BHF-UCL P negative regulation of cell proliferation
GO:0006591 IMP:BHF-UCL P ornithine metabolic process
GO:0055091 ISS:BHF-UCL P phospholipid homeostasis
GO:2000189 ISS:BHF-UCL P positive regulation of cholesterol homeostasis
GO:0045944 IMP:BHF-UCL P positive regulation of transcription from RNA polymerase II promoter
GO:0045893 IDA:BHF-UCL P positive regulation of transcription, DNA-templated
GO:0010470 IEA:Ensembl P regulation of gastrulation
GO:0060398 NAS:BHF-UCL P regulation of growth hormone receptor signaling pathway
GO:0050796 ISS:BHF-UCL P regulation of insulin secretion
GO:0019216 IDA:BHF-UCL P regulation of lipid metabolic process
GO:0006357 IDA:BHF-UCL P regulation of transcription from RNA polymerase II promoter
GO:0009749 ISS:BHF-UCL P response to glucose
GO:0007548 IEA:Ensembl P sex differentiation
GO:0023019 IEA:Ensembl P signal transduction involved in regulation of gene expression
GO:0006367 TAS:Reactome P transcription initiation from RNA polymerase II promoter
GO:0070328 ISS:BHF-UCL P triglyceride homeostasis
GO:0006805 IMP:BHF-UCL P xenobiotic metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
hsa04152 AMPK signaling pathway
hsa04950 Maturity onset diabetes of the young

Domain Information

InterPro Annotations

Accession Description
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR003068 Transcription factor COUP
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
hepatocyte nuclear factor 4, alpha
Protein Entry
HNF4A_HUMAN
UniProt ID
P41235
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative promoter usage, Alternative splicing; Named isoforms=7; Comment=Additional isoforms seem to exist.; Name=HNF4-Alpha-1; Synonyms=HNF-4B; IsoId=P41235-1; Sequence=Displayed; Note=Produced by alternative promoter usage.; Name=HNF4-Alpha-2; Synonyms=HNF4-A; IsoId=P41235-2; Sequence=VSP_003674; Note=Produced by alternative splicing of isoform HNF4-Alpha-1.; Name=HNF4-Alpha-3; Synonyms=HNF4-C; IsoId=P41235-3; Sequence=VSP_003675; Note=Produced by alternative splicing of isoform HNF4-Alpha-1.; Name=HNF4-Alpha-4; IsoId=P41235-4; Sequence=VSP_003673; Note=Produced by alternative splicing of isoform HNF4-Alpha-1.; Name=HNF4-Alpha-7; IsoId=P41235-5; Sequence=VSP_026030; Note=Produced by alternative promoter usage.; Name=HNF4-Alpha-8; IsoId=P41235-6; Sequence=VSP_026030, VSP_003674; Note=Produced by alternative splicing of isoform HNF4-Alpha-7.; Name=HNF4-Alpha-9; IsoId=P41235-7; Sequence=VSP_026030, VSP_003675; Note=Produced by alternative splicing of isoform HNF4-Alpha-7.;
Disease Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM
Disease Maturity-onset diabetes of the young 1 (MODY1) [MIM
Function Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
Interaction Q99967:CITED2; NbExp=3; IntAct=EBI-1049011, EBI-937732; A8MYZ6:FOXO6; NbExp=2; IntAct=EBI-1049011, EBI-8531039;
Miscellaneous Binds fatty acids.
Ptm Acetylation at Lys-458 lowers transcriptional activation by about two-fold.
Ptm Phosphorylated on tyrosine residue(s); phosphorylation is important for its DNA-binding activity. Phosphorylation may directly or indirectly play a regulatory role in the subnuclear distribution. Phosphorylation at Ser-313 by AMPK reduces the ability to form homodimers and bind DNA. {ECO
Sequence Caution Sequence=AAB48082.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=CAA54248.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=CAA61133.1; Type=Frameshift; Positions=2, 7; Evidence= ; Sequence=CAA61134.1; Type=Frameshift; Positions=2, 7; Evidence= ; Sequence=CAA61135.1; Type=Frameshift; Positions=2, 7; Evidence= ;
Similarity Belongs to the nuclear hormone receptor family. NR2 subfamily.
Similarity Contains 1 nuclear receptor DNA-binding domain.
Subcellular Location Nucleus.
Subunit Homodimerization is required for HNF4-alpha to bind to its recognition site. Interacts with PER2.
Web Resource Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/hnf4a/";
Web Resource Name=Wikipedia; Note=Hepatocyte nuclear factors entry; URL="http://en.wikipedia.org/wiki/Hepatocyte_nuclear_factors";

Identical and Related Proteins

Unique RefSeq proteins for LMP001210 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31077207 RefSeq NP_849180 464 hepatocyte nuclear factor 4-alpha isoform HNF4alpha1
385298694 RefSeq NP_001274111 467 hepatocyte nuclear factor 4-alpha isoform HNF4alpha10
385298694 RefSeq NP_001274112 467 hepatocyte nuclear factor 4-alpha isoform HNF4alpha11
385298694 RefSeq NP_001274113 467 hepatocyte nuclear factor 4-alpha isoform HNF4alpha12
31077205 RefSeq NP_000448 474 hepatocyte nuclear factor 4-alpha isoform HNF4alpha2
31077209 RefSeq NP_849181 417 hepatocyte nuclear factor 4-alpha isoform HNF4alpha3
385298694 RefSeq NP_001245284 467 hepatocyte nuclear factor 4-alpha isoform HNF4alpha4
71725341 RefSeq NP_001025174 442 hepatocyte nuclear factor 4-alpha isoform HNF4alpha7
71725339 RefSeq NP_787110 452 hepatocyte nuclear factor 4-alpha isoform HNF4alpha8
71725336 RefSeq NP_001025175 395 hepatocyte nuclear factor 4-alpha isoform HNF4alpha9

Identical Sequences to LMP001210 proteins

Reference Database Accession Length Protein Name
GI:31077205 DBBJ BAG73239.1 474 hepatocyte nuclear factor 4, alpha, partial [synthetic construct]
GI:71725341 GenBank AAT91237.1 442 hepatocyte nuclear factor 4 alpha, transcript variant 7 [Homo sapiens]
GI:71725339 GenBank AAT91238.1 452 hepatocyte nuclear factor 4 alpha, transcript variant 8 [Homo sapiens]
GI:71725336 GenBank AAT91239.1 395 hepatocyte nuclear factor 4 alpha, transcript variant 9 [Homo sapiens]
GI:71725339 GenBank EAW75921.1 452 hepatocyte nuclear factor 4, alpha, isoform CRA_a [Homo sapiens]
GI:385298694 GenBank EAW75923.1 467 hepatocyte nuclear factor 4, alpha, isoform CRA_c [Homo sapiens]
GI:385298694 GenBank EAW75923.1 467 hepatocyte nuclear factor 4, alpha, isoform CRA_c [Homo sapiens]
GI:385298694 GenBank EAW75923.1 467 hepatocyte nuclear factor 4, alpha, isoform CRA_c [Homo sapiens]
GI:385298694 GenBank EAW75923.1 467 hepatocyte nuclear factor 4, alpha, isoform CRA_c [Homo sapiens]
GI:31077209 GenBank EAW75924.1 417 hepatocyte nuclear factor 4, alpha, isoform CRA_d [Homo sapiens]
GI:31077209 GenBank AAI37541.1 417 Hepatocyte nuclear factor 4, alpha [Homo sapiens]
GI:31077209 GenBank AAI37540.1 417 Hepatocyte nuclear factor 4, alpha [Homo sapiens]
GI:385298694 GenBank ACP57434.1 467 Sequence 1563 from patent US 7482117
GI:385298694 GenBank ACP57434.1 467 Sequence 1563 from patent US 7482117
GI:385298694 GenBank ACP57434.1 467 Sequence 1563 from patent US 7482117
GI:385298694 GenBank ACP57434.1 467 Sequence 1563 from patent US 7482117
GI:71725339 GenBank ACP57435.1 452 Sequence 1564 from patent US 7482117
GI:31077209 GenBank ACP57437.1 417 Sequence 1566 from patent US 7482117
GI:31077205 GenBank ACP57438.1 474 Sequence 1567 from patent US 7482117
GI:385298694 GenBank ADS31031.1 467 Sequence 1563 from patent US 7781168
GI:385298694 GenBank ADS31031.1 467 Sequence 1563 from patent US 7781168
GI:385298694 GenBank ADS31031.1 467 Sequence 1563 from patent US 7781168
GI:385298694 GenBank ADS31031.1 467 Sequence 1563 from patent US 7781168
GI:71725339 GenBank ADS31032.1 452 Sequence 1564 from patent US 7781168
GI:31077209 GenBank ADS31034.1 417 Sequence 1566 from patent US 7781168
GI:31077205 GenBank ADS31035.1 474 Sequence 1567 from patent US 7781168
GI:31077207 GenBank ADZ17371.1 464 hepatocyte nuclear factor 4 4 alpha variant 1 [Homo sapiens]
GI:71725339 GenBank ADZ17379.1 452 hepatocyte nuclear factor 4 4 alpha variant 4 [Homo sapiens]
GI:31077205 GenBank ADZ17380.1 474 hepatocyte nuclear factor 4 4 alpha variant 2 [Homo sapiens]
GI:31077205 GenBank AHE01228.1 474 Sequence 56144 from patent US 8586006
GI:31077207 GenBank AHE01229.1 464 Sequence 56145 from patent US 8586006
GI:31077209 GenBank AIC48956.1 417 HNF4A, partial [synthetic construct]
GI:31077205 SwissProt P41235.3 474 RecName: Full=Hepatocyte nuclear factor 4-alpha; Short=HNF-4-alpha; AltName: Full=Nuclear receptor subfamily 2 group A member 1; AltName: Full=Transcription factor 14; Short=TCF-14; AltName: Full=Transcription factor HNF-4 [Homo sapiens]

Related Sequences to LMP001210 proteins

Reference Database Accession Length Protein Name
GI:385298694 EMBL CAA89989.1 504 hepatocyte nuclear factor 4 alpha (HNF4alpha4) [Homo sapiens]
GI:385298694 EMBL CAA89989.1 504 hepatocyte nuclear factor 4 alpha (HNF4alpha4) [Homo sapiens]
GI:385298694 EMBL CAA89989.1 504 hepatocyte nuclear factor 4 alpha (HNF4alpha4) [Homo sapiens]
GI:385298694 EMBL CAA89989.1 504 hepatocyte nuclear factor 4 alpha (HNF4alpha4) [Homo sapiens]
GI:71725336 EMBL CAA61135.1 408 Hepatocyte nuclear factor 4C [Homo sapiens]
GI:31077209 EMBL CAA61135.1 408 Hepatocyte nuclear factor 4C [Homo sapiens]
GI:385298694 GenBank AAB48082.1 516 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:385298694 GenBank AAB48082.1 516 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:385298694 GenBank AAB48082.1 516 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:385298694 GenBank AAB48082.1 516 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:31077209 GenBank AAB48083.1 408 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:71725336 GenBank AAB48083.1 408 hepatocyte nuclear factor 4-alpha [Homo sapiens]
GI:385298694 GenBank AAE59553.1 567 Sequence 131 from patent US 6187533
GI:385298694 GenBank AAE59553.1 567 Sequence 131 from patent US 6187533
GI:385298694 GenBank AAE59553.1 567 Sequence 131 from patent US 6187533
GI:31077209 GenBank AAE59553.1 567 Sequence 131 from patent US 6187533
GI:385298694 GenBank AAE59553.1 567 Sequence 131 from patent US 6187533
GI:385298694 GenBank AAE59555.1 516 Sequence 140 from patent US 6187533
GI:385298694 GenBank AAE59555.1 516 Sequence 140 from patent US 6187533
GI:385298694 GenBank AAE59555.1 516 Sequence 140 from patent US 6187533
GI:385298694 GenBank AAE59555.1 516 Sequence 140 from patent US 6187533
GI:71725341 GenBank EAW75921.1 452 hepatocyte nuclear factor 4, alpha, isoform CRA_a [Homo sapiens]
GI:71725336 GenBank EAW75924.1 417 hepatocyte nuclear factor 4, alpha, isoform CRA_d [Homo sapiens]
GI:71725336 GenBank AAI37540.1 417 Hepatocyte nuclear factor 4, alpha [Homo sapiens]
GI:31077205 GenBank ACM84795.1 471 Sequence 10293 from patent US 6812339
GI:71725341 GenBank ADS31032.1 452 Sequence 1564 from patent US 7781168
GI:71725341 GenBank ADZ17379.1 452 hepatocyte nuclear factor 4 4 alpha variant 4 [Homo sapiens]
GI:31077207 GenBank AHE01228.1 474 Sequence 56144 from patent US 8586006
GI:71725336 GenBank AIC48956.1 417 HNF4A, partial [synthetic construct]
GI:385298694 PRF - 504 hepatocyte nuclear factor 4:ISOTYPE=alpha [Homo sapiens]
GI:385298694 PRF - 504 hepatocyte nuclear factor 4:ISOTYPE=alpha [Homo sapiens]
GI:385298694 PRF - 504 hepatocyte nuclear factor 4:ISOTYPE=alpha [Homo sapiens]
GI:385298694 PRF - 504 hepatocyte nuclear factor 4:ISOTYPE=alpha [Homo sapiens]
GI:71725341 RefSeq NP_787110.2 452 hepatocyte nuclear factor 4-alpha isoform HNF4alpha8 [Homo sapiens]
GI:31077209 RefSeq XP_003253649.1 418 PREDICTED: hepatocyte nuclear factor 4-alpha isoform 1 [Nomascus leucogenys]
GI:71725336 RefSeq XP_003253650.1 396 PREDICTED: hepatocyte nuclear factor 4-alpha isoform 2 [Nomascus leucogenys]
GI:31077205 RefSeq XP_003825973.1 474 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Pan paniscus]
GI:31077207 RefSeq XP_003825974.1 464 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Pan paniscus]
GI:31077205 RefSeq XP_003936451.1 474 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Saimiri boliviensis boliviensis]
GI:31077207 RefSeq XP_003936452.1 464 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Saimiri boliviensis boliviensis]
GI:31077209 RefSeq XP_004332462.1 425 PREDICTED: LOW QUALITY PROTEIN: hepatocyte nuclear factor 4, alpha [Tursiops truncatus]
GI:71725339 RefSeq XP_004585888.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Ochotona princeps]
GI:71725339 RefSeq XP_005214696.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Bos taurus]
GI:385298694 RefSeq XP_005260464.1 513 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens]
GI:385298694 RefSeq XP_005260464.1 513 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens]
GI:385298694 RefSeq XP_005260464.1 513 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens]
GI:385298694 RefSeq XP_005260464.1 513 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Homo sapiens]
GI:31077205 RefSeq XP_005569130.1 474 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Macaca fascicularis]
GI:31077207 RefSeq XP_005569131.1 464 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Macaca fascicularis]
GI:71725339 RefSeq XP_005569132.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Macaca fascicularis]
GI:31077209 RefSeq XP_006734551.1 399 PREDICTED: hepatocyte nuclear factor 4-alpha [Leptonychotes weddellii]
GI:31077205 RefSeq XP_008014841.1 474 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Chlorocebus sabaeus]
GI:31077207 RefSeq XP_008014850.1 464 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Chlorocebus sabaeus]
GI:71725339 RefSeq XP_008014858.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Chlorocebus sabaeus]
GI:71725341 RefSeq XP_008014867.1 442 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X4 [Chlorocebus sabaeus]
GI:71725339 RefSeq XP_008949558.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Pan paniscus]
GI:71725341 RefSeq XP_008949560.1 442 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X4 [Pan paniscus]
GI:31077205 RefSeq XP_010382581.1 474 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X1 [Rhinopithecus roxellana]
GI:31077207 RefSeq XP_010382582.1 464 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X2 [Rhinopithecus roxellana]
GI:71725339 RefSeq XP_010382584.1 452 PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Rhinopithecus roxellana]