Gene/Proteome Database (LMPD)

LMPD ID
LMP001422
Gene ID
14245
Species
Mus musculus (Mouse)
Gene Name
lipin 1
Gene Symbol
Lpin1
Synonyms
4631420P06; Kiaa0188; Lipin1; fld; mKIAA0188
Chromosome
12
Map Location
12 A1.1|12 7.9 cM

Proteins

phosphatidate phosphatase LPIN1 isoform a
Refseq ID NP_001123884
Protein GI 194353985
UniProt ID Q91ZP3
mRNA ID NM_001130412
Length 891
RefSeq Status VALIDATED
MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNTSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTYPQSASYPSSDREWSPSPSPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLGSRKTPDKMNFQAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSSHLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA
phosphatidate phosphatase LPIN1 isoform a
Refseq ID NP_766538
Protein GI 68510037
UniProt ID Q91ZP3
mRNA ID NM_172950
Length 891
RefSeq Status VALIDATED
Protein sequence is identical to GI:194353985 (mRNA isoform)
phosphatidate phosphatase LPIN1 isoform b
Refseq ID NP_056578
Protein GI 27923941
UniProt ID Q91ZP3
mRNA ID NM_015763
Length 924
RefSeq Status VALIDATED
MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNTSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTYPQSASYPSSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLGSRKTPDKMNFQAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSSHLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA

Gene Information

Entrez Gene ID
14245
Gene Name
lipin 1
Gene Symbol
Lpin1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:MGI C nucleus
GO:0005667 IDA:MGI C transcription factor complex
GO:0001085 IDA:MGI F RNA polymerase II transcription factor binding
GO:0042826 IDA:MGI F histone deacetylase binding
GO:0008195 IDA:MGI F phosphatidate phosphatase activity
GO:0031532 IMP:MGI P actin cytoskeleton reorganization
GO:0032869 IMP:MGI P cellular response to insulin stimulus
GO:0016311 IDA:GOC P dephosphorylation
GO:0009062 IEA:InterPro P fatty acid catabolic process
GO:0006629 IMP:MGI P lipid metabolic process
GO:0000122 IGI:MGI P negative regulation of transcription from RNA polymerase II promoter
GO:0031065 IMP:MGI P positive regulation of histone deacetylation
GO:0045944 IGI:MGI P positive regulation of transcription from RNA polymerase II promoter
GO:0045598 IMP:MGI P regulation of fat cell differentiation
GO:0031529 IMP:MGI P ruffle organization
GO:0019432 IEA:InterPro P triglyceride biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR023214 HAD-like domain
IPR013209 LNS2, Lipin/Ned1/Smp2
IPR028794 LPIN1
IPR007651 Lipin, N-terminal

UniProt Annotations

Entry Information

Gene Name
lipin 1
Protein Entry
LPIN1_MOUSE
UniProt ID
Q91ZP3
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP001422 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
194353985 RefSeq NP_001123884 891 phosphatidate phosphatase LPIN1 isoform a
27923941 RefSeq NP_056578 924 phosphatidate phosphatase LPIN1 isoform b

Identical Sequences to LMP001422 proteins

Reference Database Accession Length Protein Name
GI:27923941 DBBJ BAB29412.1 924 unnamed protein product [Mus musculus]
GI:27923941 DBBJ BAB31786.1 924 unnamed protein product [Mus musculus]
GI:194353985 RefSeq NP_766538.2 891 phosphatidate phosphatase LPIN1 isoform a [Mus musculus]
GI:27923941 RefSeq XP_006515051.1 924 PREDICTED: phosphatidate phosphatase LPIN1 isoform X14 [Mus musculus]

Related Sequences to LMP001422 proteins

Reference Database Accession Length Protein Name
GI:194353985 DBBJ BAC27184.1 891 unnamed protein product [Mus musculus]
GI:194353985 DBBJ BAE32865.1 891 unnamed protein product [Mus musculus]
GI:194353985 GenBank AAF44296.1 891 Lpin1 [Mus musculus]
GI:27923941 GenBank AAL07798.1 924 lipin 1-b [Mus musculus]
GI:27923941 GenBank AAH42462.1 924 Lpin1 protein [Mus musculus]
GI:194353985 GenBank AAY06425.1 891 Sequence 4 from patent US 6869766
GI:27923941 GenBank AAY06426.1 924 Sequence 5 from patent US 6869766
GI:194353985 GenBank EDK98473.1 891 lipin 1, isoform CRA_a [Mus musculus]
GI:27923941 GenBank EDK98474.1 924 lipin 1, isoform CRA_b [Mus musculus]
GI:27923941 RefSeq XP_006515040.1 984 PREDICTED: phosphatidate phosphatase LPIN1 isoform X3 [Mus musculus]
GI:194353985 RefSeq XP_006515045.1 951 PREDICTED: phosphatidate phosphatase LPIN1 isoform X8 [Mus musculus]
GI:27923941 SwissProt Q91ZP3.1 924 RecName: Full=Phosphatidate phosphatase LPIN1; AltName: Full=Fatty liver dystrophy protein; AltName: Full=Lipin-1 [Mus musculus]