Gene/Proteome Database (LMPD)

LMPD ID
LMP001649
Gene ID
105787
Species
Mus musculus (Mouse)
Gene Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
Gene Symbol
Prkaa1
Synonyms
AI194361; AI450832; AL024255; AMPKalpha1; C130083N04Rik
Chromosome
15
Map Location
15 A1|15

Proteins

5'-AMP-activated protein kinase catalytic subunit alpha-1
Refseq ID NP_001013385
Protein GI 94681061
UniProt ID Q3TUQ7
mRNA ID NM_001013367
Length 559
RefSeq Status VALIDATED
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSISNYRSCQRSDSDAEAQGKPSDVSLTSSVTSLDSSPVDVAPRPGSHTIEFFEMCANLIKILAQ

Gene Information

Entrez Gene ID
105787
Gene Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
Gene Symbol
Prkaa1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0031588 IEA:Ensembl C AMP-activated protein kinase complex
GO:0016324 IEA:Ensembl C apical plasma membrane
GO:0005737 IDA:MGI C cytoplasm
GO:0004679 IEA:Ensembl F AMP-activated protein kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0000187 IEA:InterPro P activation of MAPK activity
GO:0071361 IEA:Ensembl P cellular response to ethanol
GO:0070301 IEA:Ensembl P cellular response to hydrogen peroxide
GO:0071456 IEA:Ensembl P cellular response to hypoxia
GO:0071417 IEA:Ensembl P cellular response to organonitrogen compound
GO:0009631 IEA:Ensembl P cold acclimation
GO:0055089 IEA:Ensembl P fatty acid homeostasis
GO:0019395 IMP:MGI P fatty acid oxidation
GO:0006006 IMP:MGI P glucose metabolic process
GO:2001274 IEA:Ensembl P negative regulation of glucose import in response to insulin stimulus
GO:0008284 IEA:Ensembl P positive regulation of cell proliferation
GO:0010628 IEA:Ensembl P positive regulation of gene expression
GO:0045821 IEA:Ensembl P positive regulation of glycolytic process
GO:0051291 IEA:Ensembl P protein heterooligomerization
GO:2000505 IEA:Ensembl P regulation of energy homeostasis
GO:0060627 IEA:Ensembl P regulation of vesicle-mediated transport
GO:0014823 IEA:Ensembl P response to activity
GO:0031000 IEA:Ensembl P response to caffeine

Domain Information

InterPro Annotations

Accession Description
IPR028797 5'-AMP-activated protein kinase catalytic subunit alpha-1
IPR028375 KA1 domain/Ssp2 C-terminal domain
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain
IPR008271 Serine/threonine-protein kinase, active site
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain

UniProt Annotations

Entry Information

Gene Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
Protein Entry
AAPK1_MOUSE
UniProt ID
Q3TUQ7
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP001649 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
94681061 RefSeq NP_001013385 559 5'-AMP-activated protein kinase catalytic subunit alpha-1

Identical Sequences to LMP001649 proteins

Reference Database Accession Length Protein Name
GI:94681061 SwissProt Q5EG47.2 559 RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-1; Short=AMPK subunit alpha-1; AltName: Full=Acetyl-CoA carboxylase kinase; Short=ACACA kinase; AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase; Short=HMGCR kinase; AltName: Full=Tau-protein kinase PRKAA1 [Mus musculus]

Related Sequences to LMP001649 proteins

Reference Database Accession Length Protein Name
GI:94681061 GenBank JAA13923.1 559 protein kinase, AMP-activated, alpha 1 catalytic subunit [Pan troglodytes]
GI:94681061 GenBank JAA13924.1 559 protein kinase, AMP-activated, alpha 1 catalytic subunit [Pan troglodytes]
GI:94681061 RefSeq NP_062015.2 559 5'-AMP-activated protein kinase catalytic subunit alpha-1 [Rattus norvegicus]
GI:94681061 RefSeq XP_005356642.1 559 PREDICTED: 5'-AMP-activated protein kinase catalytic subunit alpha-1 [Microtus ochrogaster]
GI:94681061 SwissProt P54645.2 559 RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-1; Short=AMPK subunit alpha-1; AltName: Full=Acetyl-CoA carboxylase kinase; Short=ACACA kinase; AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase; Short=HMGCR kinase; AltName: Full=Tau-protein kinase PRKAA1 [Rattus norvegicus]
GI:94681061 SwissProt Q13131.4 559 RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-1; Short=AMPK subunit alpha-1; AltName: Full=Acetyl-CoA carboxylase kinase; Short=ACACA kinase; AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase; Short=HMGCR kinase; AltName: Full=Tau-protein kinase PRKAA1 [Homo sapiens]