LIPID MAPS

Gene/Proteome Database (LMPD)

LMPD ID

LMP001750

Gene ID

9970

Species

Homo sapiens (Human)

Gene Name

nuclear receptor subfamily 1, group I, member 3

Gene Symbol

NR1I3

Synonyms

CAR; CAR1; MB67

Chromosome

Map Location

1q23.3

Summary

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Orthologs

View orthologs and multiple alignments for NR1I3

Proteins

nuclear receptor subfamily 1 group I member 3 isoform 1
Refseq ID	NP_001070950
Protein GI	117938756
UniProt ID	Q14994
mRNA ID	NM_001077482
Length	357
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 10
Refseq ID	NP_001070947
Protein GI	117938750
UniProt ID	Q14994
mRNA ID	NM_001077479
Length	319
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 11
Refseq ID	NP_001070938
Protein GI	117938732
UniProt ID	Q14994
mRNA ID	NM_001077470
Length	280
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 12
Refseq ID	NP_001070941
Protein GI	117938738
UniProt ID	Q14994
mRNA ID	NM_001077473
Length	315
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 13
Refseq ID	NP_001070944
Protein GI	117938744
UniProt ID	Q14994
mRNA ID	NM_001077476
Length	311
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 14
Refseq ID	NP_001070945
Protein GI	117938748
UniProt ID	Q14994
mRNA ID	NM_001077477
Length	306
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 15
Refseq ID	NP_001070943
Protein GI	117938742
UniProt ID	Q14994
mRNA ID	NM_001077475
Length	267
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 2
Refseq ID	NP_001070948
Protein GI	117938752
UniProt ID	Q14994
mRNA ID	NM_001077480
Length	352
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 3
Refseq ID	NP_005113
Protein GI	4826661
UniProt ID	Q14994
mRNA ID	NM_005122
Length	348
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 4
Refseq ID	NP_001070949
Protein GI	117938754
UniProt ID	Q14994
mRNA ID	NM_001077481
Length	314
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 5
Refseq ID	NP_001070939
Protein GI	117938734
UniProt ID	Q14994
mRNA ID	NM_001077471
Length	309
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

nuclear receptor subfamily 1 group I member 3 isoform 6
Refseq ID	NP_001070937
Protein GI	117938729
UniProt ID	Q14994
mRNA ID	NM_001077469
Length	340
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 7
Refseq ID	NP_001070946
Protein GI	117938746
UniProt ID	Q14994
mRNA ID	NM_001077478
Length	339
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 8
Refseq ID	NP_001070942
Protein GI	117938740
UniProt ID	Q14994
mRNA ID	NM_001077474
Length	296
RefSeq Status	REVIEWED
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ

nuclear receptor subfamily 1 group I member 3 isoform 9
Refseq ID	NP_001070940
Protein GI	117938736
UniProt ID	Q14994
mRNA ID	NM_001077472
Length	324
RefSeq Status	REVIEWED
MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

Gene Information

Entrez Gene ID

9970

Gene Name

nuclear receptor subfamily 1, group I, member 3

Gene Symbol

NR1I3

Species

Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	ISS:UniProtKB	C	cytoplasm
GO:0005856	IEA:UniProtKB-KW	C	cytoskeleton
GO:0005829	IEA:Ensembl	C	cytosol
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	ISS:UniProtKB	C	nucleus
GO:0003677	TAS:ProtInc	F	DNA binding
GO:0000977	IDA:NTNU_SB	F	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	IDA:NTNU_SB	F	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0004882	TAS:ProtInc	F	androgen receptor activity
GO:0004879	TAS:ProtInc	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700	TAS:ProtInc	F	sequence-specific DNA binding transcription factor activity
GO:0004887	IEA:InterPro	F	thyroid hormone receptor activity
GO:0003713	TAS:ProtInc	F	transcription coactivator activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0030521	TAS:GOC	P	androgen receptor signaling pathway
GO:0010467	TAS:Reactome	P	gene expression
GO:0030522	TAS:GOC	P	intracellular receptor signaling pathway
GO:0045892	IEA:Ensembl	P	negative regulation of transcription, DNA-templated
GO:0045944	IDA:NTNU_SB	P	positive regulation of transcription from RNA polymerase II promoter
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0006367	TAS:Reactome	P	transcription initiation from RNA polymerase II promoter

Domain Information

InterPro Annotations

Accession	Description
IPR008946	Nuclear hormone receptor, ligand-binding
IPR000536	Nuclear hormone receptor, ligand-binding, core
IPR001723	Steroid hormone receptor
IPR001728	Thyroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name

nuclear receptor subfamily 1, group I, member 3

Protein Entry

Q14994_HUMAN

UniProt ID

Q14994

Species

Human

Comments

Comment Type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=15; Name=1; IsoId=Q14994-1; Sequence=Displayed; Name=2; IsoId=Q14994-2; Sequence=VSP_010634; Name=3; IsoId=Q14994-3; Sequence=VSP_043144; Name=4; IsoId=Q14994-4; Sequence=VSP_043730, VSP_043731; Name=5; IsoId=Q14994-5; Sequence=VSP_043730, VSP_010634; Name=6; IsoId=Q14994-6; Sequence=VSP_043730, VSP_010634, VSP_043732; Name=7; IsoId=Q14994-7; Sequence=VSP_043731; Name=8; IsoId=Q14994-8; Sequence=VSP_043732; Name=9; IsoId=Q14994-9; Sequence=VSP_043730, VSP_010634, VSP_046144; Name=10; IsoId=Q14994-10; Sequence=VSP_043730, VSP_010634, VSP_043732, VSP_046144; Name=11; IsoId=Q14994-11; Sequence=VSP_043730, VSP_043732, VSP_046144; Name=12; IsoId=Q14994-12; Sequence=VSP_046144; Name=13; IsoId=Q14994-13; Sequence=VSP_055180, VSP_043732, VSP_046144; Name=14; IsoId=Q14994-15; Sequence=VSP_043731, VSP_046144; Name=15; IsoId=Q14994-16; Sequence=VSP_043730, VSP_043731, VSP_046144;
Domain	Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.
Function	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Induction	By dexamethasone.
Ptm	Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily.
Similarity	Contains 1 nuclear receptor DNA-binding domain.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7.
Subunit	Interacts with ECT2 (By similarity). Heterodimer of NR1I3 and RXR. Interacts with PSMC4. Directly interacts with DNAJC7. The DNAJC7-NR1I3 complex may also include HSP90 (By similarity).
Tissue Specificity	Predominantly expressed in liver.

Identical and Related Proteins

Unique RefSeq proteins for LMP001750 (as displayed in Record Overview)

Protein GI	Database	Accession	Length	Protein Name
117938756	RefSeq	NP_001070950	357	nuclear receptor subfamily 1 group I member 3 isoform 1
117938750	RefSeq	NP_001070947	319	nuclear receptor subfamily 1 group I member 3 isoform 10
117938732	RefSeq	NP_001070938	280	nuclear receptor subfamily 1 group I member 3 isoform 11
117938738	RefSeq	NP_001070941	315	nuclear receptor subfamily 1 group I member 3 isoform 12
117938744	RefSeq	NP_001070944	311	nuclear receptor subfamily 1 group I member 3 isoform 13
117938748	RefSeq	NP_001070945	306	nuclear receptor subfamily 1 group I member 3 isoform 14
117938742	RefSeq	NP_001070943	267	nuclear receptor subfamily 1 group I member 3 isoform 15
117938752	RefSeq	NP_001070948	352	nuclear receptor subfamily 1 group I member 3 isoform 2
4826661	RefSeq	NP_005113	348	nuclear receptor subfamily 1 group I member 3 isoform 3
117938754	RefSeq	NP_001070949	314	nuclear receptor subfamily 1 group I member 3 isoform 4
117938734	RefSeq	NP_001070939	309	nuclear receptor subfamily 1 group I member 3 isoform 5
117938729	RefSeq	NP_001070937	340	nuclear receptor subfamily 1 group I member 3 isoform 6
117938746	RefSeq	NP_001070946	339	nuclear receptor subfamily 1 group I member 3 isoform 7
117938740	RefSeq	NP_001070942	296	nuclear receptor subfamily 1 group I member 3 isoform 8
117938736	RefSeq	NP_001070940	324	nuclear receptor subfamily 1 group I member 3 isoform 9

Identical Sequences to LMP001750 proteins

Reference	Database	Accession	Length	Protein Name
GI:117938752	GenBank	AAH69626.1	352	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938732	GenBank	AAT47161.1	280	constitutive androstane receptor SV3 [Homo sapiens]
GI:117938734	GenBank	AAT47163.1	309	constitutive androstane receptor SV5 [Homo sapiens]
GI:117938736	GenBank	AAT47164.1	324	constitutive androstane receptor SV6 [Homo sapiens]
GI:117938750	GenBank	AAT47180.1	319	constitutive androstane receptor SV22 [Homo sapiens]
GI:117938756	GenBank	AAY56401.1	357	nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938734	GenBank	AAI21122.1	309	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938754	GenBank	AAI21121.1	314	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938752	GenBank	EAW52609.1	352	nuclear receptor subfamily 1, group I, member 3, isoform CRA_b [Homo sapiens]
GI:4826661	GenBank	ABP29976.1	348	Sequence 2 from patent US 7193125
GI:4826661	GenBank	ACE15472.1	348	Sequence 18 from patent US 7365160
GI:117938752	GenBank	ADQ31935.1	352	nuclear receptor subfamily 1, group I, member 3, partial [synthetic construct]
GI:117938752	GenBank	ADZ17349.1	352	constitutive androstane nuclear receptor variant 2 [Homo sapiens]
GI:4826661	GenBank	ADZ17350.1	348	constitutive androstane nuclear receptor variant 3 [Homo sapiens]
GI:117938754	GenBank	ADZ17351.1	314	constitutive androstane nuclear receptor variant 4 [Homo sapiens]
GI:117938734	GenBank	ADZ17352.1	309	constitutive androstane nuclear receptor variant 5 [Homo sapiens]
GI:4826661	GenBank	AHE01322.1	348	Sequence 56238 from patent US 8586006
GI:117938752	GenBank	AIC55691.1	352	NR1I3, partial [synthetic construct]
GI:4826661	RefSeq	NP_001129087.1	348	nuclear receptor subfamily 1 group I member 3 [Pan troglodytes]
GI:117938752	SwissProt	Q14994.2	352	RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67 [Homo sapiens]
GI:4826661	SwissProt	A2T7D9.1	348	RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive androstane receptor; Short=CAR [Pan troglodytes]

Related Sequences to LMP001750 proteins

Reference	Database	Accession	Length	Protein Name
GI:117938734	DBBJ	BAH02293.1	309	constitutive androstane receptor [Homo sapiens]
GI:117938746	GenBank	AAH69626.1	352	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:4826661	GenBank	AAH69626.1	352	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938729	GenBank	AAT47159.1	322	constitutive androstane receptor SV1, partial [Homo sapiens]
GI:117938746	GenBank	AAT47159.1	322	constitutive androstane receptor SV1, partial [Homo sapiens]
GI:117938732	GenBank	AAT47163.1	309	constitutive androstane receptor SV5 [Homo sapiens]
GI:117938754	GenBank	AAT47163.1	309	constitutive androstane receptor SV5 [Homo sapiens]
GI:117938750	GenBank	AAT47164.1	324	constitutive androstane receptor SV6 [Homo sapiens]
GI:117938740	GenBank	AAT47166.1	278	constitutive androstane receptor SV8, partial [Homo sapiens]
GI:117938740	GenBank	AAT47172.1	321	constitutive androstane receptor SV14, partial [Homo sapiens]
GI:117938729	GenBank	AAT47172.1	321	constitutive androstane receptor SV14, partial [Homo sapiens]
GI:117938746	GenBank	AAT47172.1	321	constitutive androstane receptor SV14, partial [Homo sapiens]
GI:117938752	GenBank	AAY56401.1	357	nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938754	GenBank	AAI21122.1	309	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938732	GenBank	AAI21122.1	309	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938734	GenBank	AAI21121.1	314	Nuclear receptor subfamily 1, group I, member 3 [Homo sapiens]
GI:117938734	GenBank	ADZ17351.1	314	constitutive androstane nuclear receptor variant 4 [Homo sapiens]
GI:117938754	GenBank	ADZ17352.1	309	constitutive androstane nuclear receptor variant 5 [Homo sapiens]
GI:117938732	GenBank	ADZ17352.1	309	constitutive androstane nuclear receptor variant 5 [Homo sapiens]
GI:117938729	GenBank	ADZ17385.1	353	constitutive androstane nuclear receptor [Homo sapiens]
GI:117938756	GenBank	ADZ17385.1	353	constitutive androstane nuclear receptor [Homo sapiens]
GI:117938740	RefSeq	NP_001070937.1	340	nuclear receptor subfamily 1 group I member 3 isoform 6 [Homo sapiens]
GI:117938746	RefSeq	NP_001070937.1	340	nuclear receptor subfamily 1 group I member 3 isoform 6 [Homo sapiens]
GI:117938744	RefSeq	NP_001070937.1	340	nuclear receptor subfamily 1 group I member 3 isoform 6 [Homo sapiens]
GI:117938754	RefSeq	NP_001070939.1	309	nuclear receptor subfamily 1 group I member 3 isoform 5 [Homo sapiens]
GI:117938750	RefSeq	NP_001070940.1	324	nuclear receptor subfamily 1 group I member 3 isoform 9 [Homo sapiens]
GI:117938744	RefSeq	NP_001070941.1	315	nuclear receptor subfamily 1 group I member 3 isoform 12 [Homo sapiens]
GI:117938742	RefSeq	NP_001070942.1	296	nuclear receptor subfamily 1 group I member 3 isoform 8 [Homo sapiens]
GI:117938738	RefSeq	NP_001070944.1	311	nuclear receptor subfamily 1 group I member 3 isoform 13 [Homo sapiens]
GI:117938748	RefSeq	NP_001070944.1	311	nuclear receptor subfamily 1 group I member 3 isoform 13 [Homo sapiens]
GI:117938740	RefSeq	NP_001070946.1	339	nuclear receptor subfamily 1 group I member 3 isoform 7 [Homo sapiens]
GI:117938729	RefSeq	NP_001070946.1	339	nuclear receptor subfamily 1 group I member 3 isoform 7 [Homo sapiens]
GI:117938742	RefSeq	NP_001070945.1	306	nuclear receptor subfamily 1 group I member 3 isoform 14 [Homo sapiens]
GI:4826661	RefSeq	NP_001070948.1	352	nuclear receptor subfamily 1 group I member 3 isoform 2 [Homo sapiens]
GI:117938734	RefSeq	NP_001070949.1	314	nuclear receptor subfamily 1 group I member 3 isoform 4 [Homo sapiens]
GI:117938752	RefSeq	NP_001070950.1	357	nuclear receptor subfamily 1 group I member 3 isoform 1 [Homo sapiens]
GI:4826661	RefSeq	XP_003258798.1	348	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 1 [Nomascus leucogenys]
GI:117938734	RefSeq	XP_003258799.1	309	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 2 [Nomascus leucogenys]
GI:117938750	RefSeq	XP_003258800.1	319	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 3 [Nomascus leucogenys]
GI:117938732	RefSeq	XP_003258801.1	280	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 4 [Nomascus leucogenys]
GI:4826661	RefSeq	XP_003811876.1	348	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X8 [Pan paniscus]
GI:117938742	RefSeq	XP_004027807.1	296	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 3 [Gorilla gorilla gorilla]
GI:117938740	RefSeq	XP_004027807.1	296	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 3 [Gorilla gorilla gorilla]
GI:117938746	RefSeq	XP_004027808.1	340	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 4 [Gorilla gorilla gorilla]
GI:117938729	RefSeq	XP_004027808.1	340	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 4 [Gorilla gorilla gorilla]
GI:117938740	RefSeq	XP_004027808.1	340	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 4 [Gorilla gorilla gorilla]
GI:117938732	RefSeq	XP_004027810.1	280	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 6 [Gorilla gorilla gorilla]
GI:117938742	RefSeq	XP_004027811.1	267	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 7 [Gorilla gorilla gorilla]
GI:117938748	RefSeq	XP_004027812.1	306	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 8 [Gorilla gorilla gorilla]
GI:117938738	RefSeq	XP_004027813.1	323	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform 9 [Gorilla gorilla gorilla]
GI:117938736	RefSeq	XP_005245750.1	429	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X1 [Homo sapiens]
GI:117938750	RefSeq	XP_005245751.1	424	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X2 [Homo sapiens]
GI:117938754	RefSeq	XP_005245754.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Homo sapiens]
GI:117938729	RefSeq	XP_005245754.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Homo sapiens]
GI:117938736	RefSeq	XP_005245754.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Homo sapiens]
GI:117938756	RefSeq	XP_005245754.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Homo sapiens]
GI:117938736	RefSeq	XP_008962464.1	429	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X1 [Pan paniscus]
GI:117938736	RefSeq	XP_008962465.1	425	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X2 [Pan paniscus]
GI:117938750	RefSeq	XP_003811879.2	420	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X4 [Pan paniscus]
GI:117938756	RefSeq	XP_008962467.1	357	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Pan paniscus]
GI:117938752	RefSeq	XP_008962467.1	357	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Pan paniscus]
GI:117938756	RefSeq	XP_008962468.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X6 [Pan paniscus]
GI:117938752	RefSeq	XP_008962469.1	352	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X7 [Pan paniscus]
GI:117938744	RefSeq	XP_008962471.1	416	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X9 [Pan paniscus]
GI:117938738	RefSeq	XP_008962471.1	416	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X9 [Pan paniscus]
GI:117938738	RefSeq	XP_008962472.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X10 [Pan paniscus]
GI:117938748	RefSeq	XP_008962472.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X10 [Pan paniscus]
GI:117938744	RefSeq	XP_008962472.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X10 [Pan paniscus]
GI:117938742	RefSeq	XP_008962473.1	407	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X11 [Pan paniscus]
GI:117938748	RefSeq	XP_008962473.1	407	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X11 [Pan paniscus]
GI:117938736	RefSeq	XP_009432072.1	429	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X2 [Pan troglodytes]
GI:117938736	RefSeq	XP_009432077.1	425	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X3 [Pan troglodytes]
GI:117938750	RefSeq	XP_009432083.1	420	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X5 [Pan troglodytes]
GI:117938732	RefSeq	XP_009432088.1	381	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X6 [Pan troglodytes]
GI:117938752	RefSeq	XP_009432092.1	357	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X7 [Pan troglodytes]
GI:117938756	RefSeq	XP_009432092.1	357	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X7 [Pan troglodytes]
GI:117938756	RefSeq	XP_009432093.1	353	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X8 [Pan troglodytes]
GI:117938752	RefSeq	XP_009432098.1	352	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X9 [Pan troglodytes]
GI:4826661	RefSeq	XP_009432104.1	348	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X1 [Pan troglodytes]
GI:117938754	RefSeq	XP_009432105.1	309	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X10 [Pan troglodytes]
GI:117938734	RefSeq	XP_009432105.1	309	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X10 [Pan troglodytes]
GI:117938738	RefSeq	XP_009432108.1	416	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X11 [Pan troglodytes]
GI:117938744	RefSeq	XP_009432108.1	416	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X11 [Pan troglodytes]
GI:117938748	RefSeq	XP_009432112.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X12 [Pan troglodytes]
GI:117938744	RefSeq	XP_009432112.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X12 [Pan troglodytes]
GI:117938738	RefSeq	XP_009432112.1	412	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X12 [Pan troglodytes]
GI:117938748	RefSeq	XP_009432114.1	407	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X13 [Pan troglodytes]
GI:117938742	RefSeq	XP_009432119.1	368	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoform X14 [Pan troglodytes]
GI:117938746	SwissProt	Q14994.2	352	RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67 [Homo sapiens]
GI:4826661	SwissProt	Q14994.2	352	RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67 [Homo sapiens]