Gene/Proteome Database (LMPD)
Proteins
glutaryl-CoA dehydrogenase, mitochondrial | |
---|---|
Refseq ID | NP_032123 |
Protein GI | 390190196 |
UniProt ID | Q60759 |
mRNA ID | NM_008097 |
Length | 447 |
RefSeq Status | VALIDATED |
MVPAMLTGYMSLRGVSARLLSRRSGLRFPRFPRTWSSAAAHTEKTQIRPAKSSRPVFDWKDPLILEEQLTADEKLIRDTFRNYCQERLMSRILLANRNEVFHRDIVYEMGELGVLGPTIKGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYTYGSEEQRQKYLPGLAKGELLGCFGLTEPNHGSDPGGMETRARHNPSNQSYTLSGTKTWITNSPVADLFIVWARCEDNCIRGFILEKGMRGLSAPRIEGKFSLRASATGMIIMDSVEVPEENVLPNVSSLAGPFGCLNTARYGITWGVLGAAEFCLHTARQYALDRIQFGVPLARNQLVQKKLADMLTEITLGLHACLQLGRLKDQDKATPEMVSMLKRNNCGKALDIARQARDILGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTVGK |
glutaryl-CoA dehydrogenase, mitochondrial | |
---|---|
Refseq ID | NP_001038209 |
Protein GI | 390190197 |
UniProt ID | Q8BVD4 |
mRNA ID | NM_001044744 |
Length | 447 |
RefSeq Status | VALIDATED |
Protein sequence is identical to GI:390190196 (mRNA isoform) |
Gene Information
Entrez Gene ID
Gene Name
glutaryl-Coenzyme A dehydrogenase
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005743 | IDA:MGI | C | mitochondrial inner membrane |
GO:0005739 | IDA:MGI | C | mitochondrion |
GO:0003995 | IEA:InterPro | F | acyl-CoA dehydrogenase activity |
GO:0050660 | IEA:InterPro | F | flavin adenine dinucleotide binding |
GO:0006568 | IEA:UniProtKB-UniPathway | P | tryptophan metabolic process |
KEGG Pathway Links
Domain Information
InterPro Annotations
Accession | Description |
---|---|
IPR006089 | Acyl-CoA dehydrogenase, conserved site |
IPR009075 | Acyl-CoA dehydrogenase/oxidase C-terminal |
IPR013786 | Acyl-CoA dehydrogenase/oxidase, N-terminal |
IPR009100 | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain |
IPR006091 | Acyl-CoA oxidase/dehydrogenase, central domain |
UniProt Annotations
Entry Information
Gene Name
glutaryl-Coenzyme A dehydrogenase
Protein Entry
Q8BVD4_MOUSE
UniProt ID
Species
Mouse
Comments
Comment Type | Description |
---|---|
Catalytic Activity | Glutaryl-CoA + electron-transfer flavoprotein = crotonyl-CoA + CO(2) + reduced electron-transfer flavoprotein. |
Cofactor | Name=FAD; Xref=ChEBI:CHEBI:57692; |
Function | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. |
Pathway | Amino-acid metabolism; lysine degradation. |
Pathway | Amino-acid metabolism; tryptophan metabolism. |
Similarity | Belongs to the acyl-CoA dehydrogenase family. {ECO:0000305}. |
Subcellular Location | Mitochondrion matrix. |
Subunit | Homotetramer. |
Identical and Related Proteins
Unique RefSeq proteins for LMP001751 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
390190196 | RefSeq | NP_032123 | 447 | glutaryl-CoA dehydrogenase, mitochondrial |
Identical Sequences to LMP001751 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:390190196 | RefSeq | NP_001038209.2 | 447 | glutaryl-CoA dehydrogenase, mitochondrial [Mus musculus] |
Related Sequences to LMP001751 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:390190196 | DBBJ | BAE38166.1 | 438 | unnamed protein product [Mus musculus] |
GI:390190196 | GenBank | AAH61158.1 | 438 | Glutaryl-Coenzyme A dehydrogenase [Mus musculus] |
GI:390190196 | GenBank | EDL10967.1 | 454 | glutaryl-Coenzyme A dehydrogenase, isoform CRA_a, partial [Mus musculus] |
GI:390190196 | GenBank | EDL10968.1 | 447 | glutaryl-Coenzyme A dehydrogenase, isoform CRA_b [Mus musculus] |
GI:390190196 | RefSeq | NP_001102366.1 | 447 | glutaryl-CoA dehydrogenase, mitochondrial [Rattus norvegicus] |
GI:390190196 | SwissProt | Q60759.2 | 438 | RecName: Full=Glutaryl-CoA dehydrogenase, mitochondrial; Short=GCD; Flags: Precursor [Mus musculus] |