Gene/Proteome Database (LMPD)

LMPD ID
LMP001812
Gene ID
11307
Species
Mus musculus (Mouse)
Gene Name
ATP-binding cassette, sub-family G (WHITE), member 1
Gene Symbol
Abcg1
Synonyms
AW413978; Abc8; White
Chromosome
17
Map Location
17|17
Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The human protein is involved in macrophage cholesterol efflux and may regulate cellular lipid homeostasis in other cell types. [provided by RefSeq, Jul 2008]
Orthologs
View orthologs and multiple alignments for Abcg1

Proteins

ATP-binding cassette sub-family G member 1
Refseq ID NP_033723
Protein GI 6752940
UniProt ID Q0VDW9
mRNA ID NM_009593
Length 666
RefSeq Status REVIEWED
MACLMAAFSVGTAMNASSYSAAMTEPKSVCVSVDEVVSSNVDEVETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFKDLSYSVPEGPWWKKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDADYKRDLGGDTDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER

Gene Information

Entrez Gene ID
11307
Gene Name
ATP-binding cassette, sub-family G (WHITE), member 1
Gene Symbol
Abcg1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:Ensembl C Golgi apparatus
GO:0009897 IEA:Ensembl C external side of plasma membrane
GO:0016021 IEA:InterPro C integral component of membrane
GO:0005739 IEA:Ensembl C mitochondrion
GO:0043531 IEA:Ensembl F ADP binding
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0017127 IEA:Ensembl F cholesterol transporter activity
GO:0034437 IEA:Ensembl F glycoprotein transporter activity
GO:0005548 IEA:Ensembl F phospholipid transporter activity
GO:0034041 IEA:Ensembl F sterol-transporting ATPase activity
GO:0019534 IEA:Ensembl F toxin transporter activity
GO:0042987 IEA:Ensembl P amyloid precursor protein catabolic process
GO:0033344 IEA:Ensembl P cholesterol efflux
GO:0042632 IEA:Ensembl P cholesterol homeostasis
GO:0008203 IEA:Ensembl P cholesterol metabolic process
GO:0030301 IDA:MGI P cholesterol transport
GO:0032367 IEA:Ensembl P intracellular cholesterol transport
GO:0033700 IEA:Ensembl P phospholipid efflux
GO:0055091 IEA:Ensembl P phospholipid homeostasis
GO:0033993 IEA:Ensembl P response to lipid

Domain Information

InterPro Annotations

Accession Description
IPR003593 AAA+ ATPase domain
IPR020064 ABC transporter, G1
IPR017871 ABC transporter, conserved site
IPR013525 ABC-2 type transporter
IPR003439 ABC_transporter-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR005284 Pigment precursor permease

UniProt Annotations

Entry Information

Gene Name
ATP-binding cassette, sub-family G (WHITE), member 1
Protein Entry
ABCG1_MOUSE
UniProt ID
Q0VDW9
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP001812 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6752940 RefSeq NP_033723 666 ATP-binding cassette sub-family G member 1

Identical Sequences to LMP001812 proteins

Reference Database Accession Length Protein Name
GI:6752940 EMBL CAA88636.1 666 ABC8 [Mus musculus]
GI:6752940 GenBank AAB47738.1 666 white homolog [Mus musculus]
GI:6752940 GenBank AAK27442.1 666 ATP-binding cassette transporter G1 [Mus musculus]
GI:6752940 GenBank AAI19472.1 666 ATP-binding cassette, sub-family G (WHITE), member 1 [Mus musculus]
GI:6752940 GenBank EDL40378.1 666 ATP-binding cassette, sub-family G (WHITE), member 1, isoform CRA_b [Mus musculus]
GI:6752940 SwissProt Q64343.1 666 RecName: Full=ATP-binding cassette sub-family G member 1; AltName: Full=ATP-binding cassette transporter 8; AltName: Full=White protein homolog [Mus musculus]

Related Sequences to LMP001812 proteins

Reference Database Accession Length Protein Name
GI:6752940 EMBL CAC21556.1 666 ABC transporter, white homologue [Rattus norvegicus]
GI:6752940 GenBank EDL96995.1 666 ATP-binding cassette, sub-family G (WHITE), member 1, isoform CRA_a [Rattus norvegicus]
GI:6752940 GenBank ERE86824.1 666 ATP-binding cassette sub-family G member 1 [Cricetulus griseus]
GI:6752940 RefSeq NP_445954.1 666 ATP-binding cassette sub-family G member 1 [Rattus norvegicus]
GI:6752940 RefSeq XP_005070727.1 666 PREDICTED: ATP-binding cassette sub-family G member 1 isoform X2 [Mesocricetus auratus]
GI:6752940 RefSeq XP_005360367.1 666 PREDICTED: ATP-binding cassette sub-family G member 1 isoform X2 [Microtus ochrogaster]