Gene/Proteome Database (LMPD)

LMPD ID
LMP001856
Gene ID
70383
Species
Mus musculus (Mouse)
Gene Name
cytochrome c oxidase assembly protein 10
Gene Symbol
Cox10
Synonyms
2410004F01Rik; AU042636
Chromosome
11
Map Location
11 B3|11

Proteins

protoheme IX farnesyltransferase, mitochondrial
Refseq ID NP_848466
Protein GI 30410008
UniProt ID Q3U3N1
mRNA ID NM_178379
Length 443
RefSeq Status VALIDATED
MAASPHTISSRLLTGSVGGCIWYLERRAIQGLPHRVTRLFRNVSNQWVTLQHLSFLKRMYVTQLHRGLSQRVKPKPEPPASPFLEHTSSGQARADEDELPSFPAPSRPLSRKPNEELVELEATSIVDHSLDTAKEKKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPGPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSITNTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTAAPVLDITTWVFPVISLPINLYISYLGFRFYVDADRRSSRKLFFCSLWHLPLLLLLMLTCKQRPGQEGDKGEAPS

Gene Information

Entrez Gene ID
70383
Gene Name
cytochrome c oxidase assembly protein 10
Gene Symbol
Cox10
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:InterPro C integral component of membrane
GO:0031966 IEA:UniProtKB-SubCell C mitochondrial membrane
GO:0005739 IDA:MGI C mitochondrion
GO:0004129 IEA:Ensembl F cytochrome-c oxidase activity
GO:0008495 IEA:InterPro F protoheme IX farnesyltransferase activity
GO:0009060 IMP:MGI P aerobic respiration
GO:0017004 IDA:MGI P cytochrome complex assembly
GO:0006784 IDA:MGI P heme a biosynthetic process
GO:0048034 IEA:InterPro P heme O biosynthetic process
GO:0000266 IMP:MGI P mitochondrial fission
GO:0007005 IMP:MGI P mitochondrion organization
GO:0008535 IEA:Ensembl P respiratory chain complex IV assembly

Domain Information

InterPro Annotations

Accession Description
IPR006369 Protohaem IX farnesyltransferase
IPR016315 Protohaem IX farnesyltransferase, mitochondria
IPR000537 UbiA prenyltransferase family

UniProt Annotations

Entry Information

Gene Name
cytochrome c oxidase assembly protein 10
Protein Entry
COX10_MOUSE
UniProt ID
Q3U3N1
Species
Mouse

Comments

Comment Type Description
Function Converts protoheme IX and farnesyl diphosphate to heme O.
Similarity Belongs to the ubiA prenyltransferase family.
Subcellular Location Mitochondrion membrane .

Identical and Related Proteins

Unique RefSeq proteins for LMP001856 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30410008 RefSeq NP_848466 443 protoheme IX farnesyltransferase, mitochondrial

Identical Sequences to LMP001856 proteins

Reference Database Accession Length Protein Name
GI:30410008 DBBJ BAE32754.1 443 unnamed protein product [Mus musculus]
GI:30410008 GenBank AAH38046.1 443 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) [Mus musculus]
GI:30410008 GenBank EDL10389.1 443 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast), isoform CRA_a [Mus musculus]
GI:30410008 SwissProt Q8CFY5.1 443 RecName: Full=Protoheme IX farnesyltransferase, mitochondrial; AltName: Full=Heme O synthase; Flags: Precursor [Mus musculus]

Related Sequences to LMP001856 proteins

Reference Database Accession Length Protein Name
GI:30410008 DBBJ BAE42594.1 443 unnamed protein product [Mus musculus]
GI:30410008 DBBJ BAE29227.1 431 unnamed protein product, partial [Mus musculus]
GI:30410008 GenBank EDM04748.1 442 rCG34472, isoform CRA_b [Rattus norvegicus]
GI:30410008 RefSeq XP_003752384.1 442 PREDICTED: protoheme IX farnesyltransferase, mitochondrial isoform X1 [Rattus norvegicus]
GI:30410008 RefSeq XP_005067681.1 443 PREDICTED: protoheme IX farnesyltransferase, mitochondrial-like [Mesocricetus auratus]
GI:30410008 RefSeq XP_005349926.1 443 PREDICTED: protoheme IX farnesyltransferase, mitochondrial-like [Microtus ochrogaster]