Gene/Proteome Database (LMPD)

LMPD ID
LMP002089
Gene ID
13072
Species
Mus musculus (Mouse)
Gene Name
cytochrome P450, family 11, subfamily b, polypeptide 2
Gene Symbol
Cyp11b2
Synonyms
Cpn2; Cyp11b; Cyp11b-2
Chromosome
15
Map Location
15 D3|15 34.29 cM

Proteins

cytochrome P450 11B2, mitochondrial
Refseq ID NP_034121
Protein GI 226823208
UniProt ID P15539
mRNA ID NM_009991
Length 502
RefSeq Status VALIDATED
MAMALRVTADVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHRELRGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFLPKSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQMAYRFVLMPSSSPVLTFRPVS

Gene Information

Entrez Gene ID
13072
Gene Name
cytochrome P450, family 11, subfamily b, polypeptide 2
Gene Symbol
Cyp11b2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:MGI C mitochondrion
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0004507 IDA:MGI F steroid 11-beta-monooxygenase activity
GO:0032342 IDA:MGI P aldosterone biosynthetic process
GO:0042756 IMP:MGI P drinking behavior
GO:0050801 IMP:MGI P ion homeostasis
GO:0002017 IMP:MGI P regulation of blood volume by renal aldosterone
GO:0001991 IMP:MGI P regulation of systemic arterial blood pressure by circulatory renin-angiotensin

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR017972 Cytochrome P450, conserved site
IPR002399 Cytochrome P450, mitochondrial

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 11, subfamily b, polypeptide 2
Protein Entry
C11B2_MOUSE
UniProt ID
P15539
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP002089 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
226823208 RefSeq NP_034121 502 cytochrome P450 11B2, mitochondrial

Identical Sequences to LMP002089 proteins

Reference Database Accession Length Protein Name
GI:226823208 GenBank EDL29457.1 502 mCG2779, isoform CRA_b [Mus musculus]

Related Sequences to LMP002089 proteins

Reference Database Accession Length Protein Name
GI:226823208 GenBank AAB21517.2 500 aldosterone synthase [Mus sp.]
GI:226823208 GenBank AAI16909.1 500 Cytochrome P450, family 11, subfamily b, polypeptide 2 [Mus musculus]
GI:226823208 GenBank AAI19322.1 500 Cytochrome P450, family 11, subfamily b, polypeptide 2 [Mus musculus]
GI:226823208 GenBank EDM16079.1 502 rCG59633 [Rattus norvegicus]
GI:226823208 RefSeq NP_036670.2 502 cytochrome P450 11B2, mitochondrial [Rattus norvegicus]
GI:226823208 SwissProt P15539.3 500 RecName: Full=Cytochrome P450 11B2, mitochondrial; AltName: Full=Aldosterone synthase; AltName: Full=CYPXIB2; AltName: Full=Cytochrome P450C11; AltName: Full=Steroid 11-beta-hydroxylase; Flags: Precursor [Mus musculus]