Gene/Proteome Database (LMPD)

LMPD ID
LMP002267
Gene ID
13116
Species
Mus musculus (Mouse)
Gene Name
cytochrome P450, family 46, subfamily a, polypeptide 1
Gene Symbol
Cyp46a1
Synonyms
Cyp46
Chromosome
12
Map Location
12|12 F2

Proteins

cholesterol 24-hydroxylase precursor
Refseq ID NP_034140
Protein GI 6753590
UniProt ID Q3US73
mRNA ID NM_010010
Length 500
RefSeq Status PROVISIONAL
MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVLQDVFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPGKRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPPPC
sig_peptide: 1..28 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2934 peptide sequence: MSPGLLLLGSAVLLAFGLCCTFVHRARS

Gene Information

Entrez Gene ID
13116
Gene Name
cytochrome P450, family 46, subfamily a, polypeptide 1
Gene Symbol
Cyp46a1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0033781 IEA:Ensembl F cholesterol 24-hydroxylase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0006707 IEA:Ensembl P cholesterol catabolic process
GO:0006805 IEA:Ensembl P xenobiotic metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR017972 Cytochrome P450, conserved site
IPR002401 Cytochrome P450, E-class, group I

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 46, subfamily a, polypeptide 1
Protein Entry
CP46A_MOUSE
UniProt ID
Q3US73
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP002267 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6753590 RefSeq NP_034140 500 cholesterol 24-hydroxylase precursor

Identical Sequences to LMP002267 proteins

Reference Database Accession Length Protein Name
GI:6753590 DBBJ BAE24462.1 500 unnamed protein product [Mus musculus]
GI:6753590 GenBank AAD41243.1 500 cholesterol 24-hydroxylase [Mus musculus]
GI:6753590 GenBank AAH18307.1 500 Cytochrome P450, family 46, subfamily a, polypeptide 1 [Mus musculus]
GI:6753590 SwissProt Q9WVK8.1 500 RecName: Full=Cholesterol 24-hydroxylase; Short=CH24H; AltName: Full=Cytochrome P450 46A1 [Mus musculus]

Related Sequences to LMP002267 proteins

Reference Database Accession Length Protein Name
GI:6753590 GenBank EDL18715.1 518 cytochrome P450, family 46, subfamily a, polypeptide 1, isoform CRA_a, partial [Mus musculus]
GI:6753590 GenBank EDL18716.1 500 cytochrome P450, family 46, subfamily a, polypeptide 1, isoform CRA_b [Mus musculus]
GI:6753590 GenBank AAI62019.1 500 Cyp46a1 protein [Rattus norvegicus]
GI:6753590 RefSeq XP_005343590.1 500 PREDICTED: cholesterol 24-hydroxylase-like [Microtus ochrogaster]
GI:6753590 RefSeq XP_006240610.1 500 PREDICTED: cholesterol 24-hydroxylase isoform X1 [Rattus norvegicus]
GI:6753590 RefSeq XP_006971754.1 500 PREDICTED: cholesterol 24-hydroxylase-like [Peromyscus maniculatus bairdii]