Gene/Proteome Database (LMPD)
Proteins
24-hydroxycholesterol 7-alpha-hydroxylase isoform 1 | |
---|---|
Refseq ID | NP_061375 |
Protein GI | 9256529 |
UniProt ID | Q544S6 |
mRNA ID | NM_018887 |
Length | 470 |
RefSeq Status | VALIDATED |
MGIMELFSPIAIAVLGSCVLFLFSRLKNLLGPPCIQGWIPWIGAGLEFGKAPLEFIEKARIKYGPVFTIFAMGNRMTFVSEEEGINVLLKSEHVDFESAVQSPVYHTAWIPKNVFSALHERLYALMKGKMGTFNTHHFTGPLTEELHEQLEGLGTHGTMDLNDFVRYLLYPATLNTLFKKGLFLTDKRTIKEFYQQFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGNIKAHGSAGHSGTLLQAILEVVETETRQYSPNYGLVVLWAALANAPPIAFWTLGYILSHPDIHRTVLESISSVFGTAGKDKIKVSEDDLKKLLIIKWCILESVRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQSSRHLVGVPQPAGKCRIEYKQRA |
24-hydroxycholesterol 7-alpha-hydroxylase isoform 2 | |
---|---|
Refseq ID | NP_001272876 |
Protein GI | 552953854 |
UniProt ID | Q544S6 |
mRNA ID | NM_001285947 |
Length | 420 |
RefSeq Status | VALIDATED |
MGIMELFSPIAIAVLGSCVLFLFSRLKNLLGPPCIQGWIPWIGAGLEFGKAPLEFIEKARIKYGPVFTIFAMGNRMTFVSEEEGINVLLKSEHVDFESAVQSPVYHTAWIPKNVFSALHERLYALMKGKMGTFNTHHFTGPLTEELHEQLEGLGTHGTMDLNDFVRNWSKSKRWLLALFEKNIGNIKAHGSAGHSGTLLQAILEVVETETRQYSPNYGLVVLWAALANAPPIAFWTLGYILSHPDIHRTVLESISSVFGTAGKDKIKVSEDDLKKLLIIKWCILESVRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQSSRHLVGVPQPAGKCRIEYKQRA |
24-hydroxycholesterol 7-alpha-hydroxylase isoform 3 | |
---|---|
Refseq ID | NP_001272877 |
Protein GI | 552953856 |
UniProt ID | Q544S6 |
mRNA ID | NM_001285948 |
Length | 404 |
RefSeq Status | VALIDATED |
MGIMELFSPIAIAVLGSCVLFLFSRLKNLLGPPCIQGWIPWIGAGLEFGKAPLEFIEKARIKYGPVFTIFAMGNRMTFVSEEEGINVLLKSEHVDFESAVQSPVYHTAWIPKNVFSALHERLYALMKGKMGTFNTHHFTGPLTEELHEQLEGLGTHGTMDLNDFVRYLLYPATLNTLFKKGLFLTDKRTIKEFYQQFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGNIKAHGSAGHSGTLLQAILEVVETETRQYSPNYGLVVLWAALANAPPIAFWTLGYILSHPDIHRTVLESISSVFGTAGKDKIKVSEDDLKKLLIIKWCILESVRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPVVCSLRDSTMHYLSAV |
Gene Information
Entrez Gene ID
Gene Name
cytochrome P450, family 39, subfamily a, polypeptide 1
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005789 | IEA:UniProtKB-SubCell | C | endoplasmic reticulum membrane |
GO:0020037 | IEA:InterPro | F | heme binding |
GO:0005506 | IEA:InterPro | F | iron ion binding |
GO:0008396 | IEA:Ensembl | F | oxysterol 7-alpha-hydroxylase activity |
GO:0008387 | IDA:MGI | F | steroid 7-alpha-hydroxylase activity |
GO:0006699 | IEA:Ensembl | P | bile acid biosynthetic process |
GO:0006707 | IDA:MGI | P | cholesterol catabolic process |
Domain Information
UniProt Annotations
Entry Information
Gene Name
cytochrome P450, family 39, subfamily a, polypeptide 1
Protein Entry
Q544S6_MOUSE
UniProt ID
Species
Mouse
Comments
Comment Type | Description |
---|---|
Cofactor | Note=Heme group. {ECO:0000256|PIRNR:PIRNR000047, ECO:0000256|PIRSR:PIRSR000047-1}; |
Similarity | Belongs to the cytochrome P450 family. |
Subcellular Location | Endoplasmic reticulum membrane . |
Identical and Related Proteins
Unique RefSeq proteins for LMP002294 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
9256529 | RefSeq | NP_061375 | 470 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform 1 |
552953854 | RefSeq | NP_001272876 | 420 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform 2 |
552953856 | RefSeq | NP_001272877 | 404 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform 3 |
Identical Sequences to LMP002294 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:9256529 | DBBJ | BAC27530.1 | 470 | unnamed protein product [Mus musculus] |
GI:9256529 | GenBank | AAF63328.1 | 470 | oxysterol 7alpha-hydroxylase [Mus musculus] |
GI:552953854 | GenBank | EDL23411.1 | 420 | cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_a [Mus musculus] |
GI:9256529 | GenBank | EDL23413.1 | 470 | cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_c [Mus musculus] |
GI:9256529 | SwissProt | Q9JKJ9.1 | 470 | RecName: Full=24-hydroxycholesterol 7-alpha-hydroxylase; AltName: Full=Cytochrome P450 39A1; Short=mCYP39A1; AltName: Full=Oxysterol 7-alpha-hydroxylase [Mus musculus] |
Related Sequences to LMP002294 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:552953856 | DBBJ | BAC27530.1 | 470 | unnamed protein product [Mus musculus] |
GI:552953854 | DBBJ | BAC27530.1 | 470 | unnamed protein product [Mus musculus] |
GI:552953854 | GenBank | AAF63328.1 | 470 | oxysterol 7alpha-hydroxylase [Mus musculus] |
GI:552953854 | GenBank | AAH37663.1 | 420 | Cyp39a1 protein [Mus musculus] |
GI:552953856 | GenBank | AAH21418.1 | 404 | Cyp39a1 protein [Mus musculus] |
GI:552953856 | GenBank | EDL23412.1 | 407 | cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_b, partial [Mus musculus] |
GI:552953854 | GenBank | EDL23413.1 | 470 | cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_c [Mus musculus] |
GI:552953856 | GenBank | EDL23413.1 | 470 | cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_c [Mus musculus] |
GI:9256529 | GenBank | EDM18705.1 | 465 | cytochrome P450, family 39, subfamily a, polypeptide 1 (predicted), isoform CRA_a [Rattus norvegicus] |
GI:552953854 | RefSeq | NP_061375.1 | 470 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform 1 [Mus musculus] |
GI:552953856 | RefSeq | NP_061375.1 | 470 | 24-hydroxycholesterol 7-alpha-hydroxylase isoform 1 [Mus musculus] |
GI:9256529 | RefSeq | NP_001100363.1 | 465 | 24-hydroxycholesterol 7-alpha-hydroxylase [Rattus norvegicus] |
GI:9256529 | RefSeq | XP_006244666.1 | 482 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X3 [Rattus norvegicus] |
GI:9256529 | RefSeq | XP_006244667.1 | 470 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X4 [Rattus norvegicus] |
GI:9256529 | RefSeq | XP_008765076.1 | 495 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X1 [Rattus norvegicus] |
GI:9256529 | RefSeq | XP_008765077.1 | 483 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X2 [Rattus norvegicus] |
GI:552953854 | SwissProt | Q9JKJ9.1 | 470 | RecName: Full=24-hydroxycholesterol 7-alpha-hydroxylase; AltName: Full=Cytochrome P450 39A1; Short=mCYP39A1; AltName: Full=Oxysterol 7-alpha-hydroxylase [Mus musculus] |
GI:552953856 | SwissProt | Q9JKJ9.1 | 470 | RecName: Full=24-hydroxycholesterol 7-alpha-hydroxylase; AltName: Full=Cytochrome P450 39A1; Short=mCYP39A1; AltName: Full=Oxysterol 7-alpha-hydroxylase [Mus musculus] |