Gene/Proteome Database (LMPD)

LMPD ID
LMP002419
Gene ID
6483
Species
Homo sapiens (Human)
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Gene Symbol
ST3GAL2
Synonyms
Gal-NAc6S; SIAT4B; ST3GALII; ST3GalA.2
Chromosome
16
Map Location
16q22.1
Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. [provided by RefSeq, Jul 2008]
Orthologs
View orthologs and multiple alignments for ST3GAL2

Proteins

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2
Refseq ID NP_008858
Protein GI 5902082
UniProt ID Q16842
mRNA ID NM_006927
Length 350
RefSeq Status REVIEWED
MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFKSHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN

Gene Information

Entrez Gene ID
6483
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Gene Symbol
ST3GAL2
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030173 IEA:InterPro C integral component of Golgi membrane
GO:0008373 IEA:InterPro F sialyltransferase activity
GO:0006486 IEA:InterPro P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate
hsa00512 Mucin type O-Glycan biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
REACT_121120 Keratan sulfate biosynthesis
REACT_200874 Sialic acid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase

UniProt Annotations

Entry Information

Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Protein Entry
SIA4B_HUMAN
UniProt ID
Q16842
Species
Human

Identical and Related Proteins

Unique RefSeq proteins for LMP002419 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
5902082 RefSeq NP_008858 350 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

Identical Sequences to LMP002419 proteins

Reference Database Accession Length Protein Name
GI:5902082 DBBJ BAI47222.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2, partial [synthetic construct]
GI:5902082 GenBank ADC20519.1 350 Sequence 1003 from patent US 7638288
GI:5902082 GenBank ADZ15923.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2, partial [synthetic construct]
GI:5902082 GenBank AED45520.1 350 Sequence 1380 from patent US 7892730
GI:5902082 GenBank AGD01480.1 350 Sequence 1003 from patent US 8338124
GI:5902082 GenBank AIC49725.1 350 ST3GAL2, partial [synthetic construct]

Related Sequences to LMP002419 proteins

Reference Database Accession Length Protein Name
GI:5902082 GenBank JAA01397.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes]
GI:5902082 GenBank JAA01398.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes]
GI:5902082 GenBank JAA16078.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes]
GI:5902082 GenBank JAA26690.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes]
GI:5902082 GenBank JAA43416.1 350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes]
GI:5902082 RefSeq XP_008953062.1 350 PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 [Pan paniscus]