Gene/Proteome Database (LMPD)
LMPD ID
LMP002419
Gene ID
Species
Homo sapiens (Human)
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Gene Symbol
Synonyms
Gal-NAc6S; SIAT4B; ST3GALII; ST3GalA.2
Chromosome
16
Map Location
16q22.1
Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. [provided by RefSeq, Jul 2008]
Orthologs
Proteins
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 | |
|---|---|
| Refseq ID | NP_008858 |
| Protein GI | 5902082 |
| UniProt ID | Q16842 |
| mRNA ID | NM_006927 |
| Length | 350 |
| RefSeq Status | REVIEWED |
| MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFKSHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN | |
Gene Information
Entrez Gene ID
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Gene Symbol
Species
Homo sapiens
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0030173 | IEA:InterPro | C | integral component of Golgi membrane |
| GO:0008373 | IEA:InterPro | F | sialyltransferase activity |
| GO:0006486 | IEA:InterPro | P | protein glycosylation |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate |
| hsa00512 | Mucin type O-Glycan biosynthesis |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| REACT_121120 | Keratan sulfate biosynthesis |
| REACT_200874 | Sialic acid metabolism |
Domain Information
UniProt Annotations
Entry Information
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Protein Entry
SIA4B_HUMAN
UniProt ID
Species
Human
Identical and Related Proteins
Unique RefSeq proteins for LMP002419 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 5902082 | RefSeq | NP_008858 | 350 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 |
Identical Sequences to LMP002419 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:5902082 | DBBJ | BAI47222.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2, partial [synthetic construct] |
| GI:5902082 | GenBank | ADC20519.1 | 350 | Sequence 1003 from patent US 7638288 |
| GI:5902082 | GenBank | ADZ15923.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2, partial [synthetic construct] |
| GI:5902082 | GenBank | AED45520.1 | 350 | Sequence 1380 from patent US 7892730 |
| GI:5902082 | GenBank | AGD01480.1 | 350 | Sequence 1003 from patent US 8338124 |
| GI:5902082 | GenBank | AIC49725.1 | 350 | ST3GAL2, partial [synthetic construct] |
Related Sequences to LMP002419 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:5902082 | GenBank | JAA01397.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes] |
| GI:5902082 | GenBank | JAA01398.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes] |
| GI:5902082 | GenBank | JAA16078.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes] |
| GI:5902082 | GenBank | JAA26690.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes] |
| GI:5902082 | GenBank | JAA43416.1 | 350 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Pan troglodytes] |
| GI:5902082 | RefSeq | XP_008953062.1 | 350 | PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 [Pan paniscus] |