Gene/Proteome Database (LMPD)

LMPD ID
LMP002557
Gene ID
13081
Species
Mus musculus (Mouse)
Gene Name
cytochrome P450, family 24, subfamily a, polypeptide 1
Gene Symbol
Cyp24a1
Synonyms
24-OHase; CP24; Cyp24
Chromosome
2
Map Location
2 H3|2 91.91 cM

Proteins

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial precursor
Refseq ID NP_034126
Protein GI 6753572
UniProt ID Q3TWW0
mRNA ID NM_009996
Length 514
RefSeq Status PROVISIONAL
MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHLGILVPSRELPIAFCPR
transit_peptide: 1..35 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (Q64441.1) calculated_mol_wt: 4044 peptide sequence: MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVK mat_peptide: 36..514 product: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q64441.1) calculated_mol_wt: 55428 peptide sequence: RAPKEVPLCPLMTDGETRNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHLGILVPSRELPIAFCPR

Gene Information

Entrez Gene ID
13081
Gene Name
cytochrome P450, family 24, subfamily a, polypeptide 1
Gene Symbol
Cyp24a1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:MGI C mitochondrion
GO:0030342 IEA:Ensembl F 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
GO:0008403 IMP:MGI F 25-hydroxycholecalciferol-24-hydroxylase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0001649 IEA:Ensembl P osteoblast differentiation
GO:0033280 IEA:Ensembl P response to vitamin D
GO:0042359 IMP:MGI P vitamin D metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 24, subfamily a, polypeptide 1
Protein Entry
CP24A_MOUSE
UniProt ID
Q3TWW0
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP002557 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6753572 RefSeq NP_034126 514 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial precursor

Identical Sequences to LMP002557 proteins

Reference Database Accession Length Protein Name
GI:6753572 DBBJ BAE35429.1 514 unnamed protein product [Mus musculus]
GI:6753572 DBBJ BAE35510.1 514 unnamed protein product [Mus musculus]
GI:6753572 DBBJ BAE35528.1 514 unnamed protein product [Mus musculus]
GI:6753572 GenBank AAI09141.1 514 Cytochrome P450, family 24, subfamily a, polypeptide 1 [Mus musculus]
GI:6753572 GenBank AAI09140.1 514 Cytochrome P450, family 24, subfamily a, polypeptide 1 [Mus musculus]
GI:6753572 GenBank EDL06583.1 514 cytochrome P450, family 24, subfamily a, polypeptide 1 [Mus musculus]

Related Sequences to LMP002557 proteins

Reference Database Accession Length Protein Name
GI:6753572 DBBJ BAE34825.1 514 unnamed protein product [Mus musculus]
GI:6753572 DBBJ BAE35118.1 514 unnamed protein product [Mus musculus]
GI:6753572 EMBL CAA42093.1 514 25-hydroxyvitamin D3 24-hydroxylase [Rattus rattus]
GI:6753572 GenBank AAA42340.1 514 25-hydroxyvitamin D3 24-hydroxylase [Rattus norvegicus]
GI:6753572 GenBank EDL96333.1 514 cytochrome P450, subfamily 24 [Rattus norvegicus]
GI:6753572 SwissProt Q09128.1 514 RecName: Full=1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Short=24-OHase; Short=Vitamin D(3) 24-hydroxylase; AltName: Full=Cytochrome P450 24A1; AltName: Full=Cytochrome P450-CC24; Flags: Precursor [Rattus norvegicus]