Gene/Proteome Database (LMPD)

LMPD ID
LMP002610
Gene ID
1381
Species
Homo sapiens (Human)
Gene Name
cellular retinoic acid binding protein 1
Gene Symbol
CRABP1
Synonyms
CRABP; CRABP-I; CRABPI; RBP5
Chromosome
15
Map Location
15q24
Summary
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]
Orthologs
View orthologs and multiple alignments for CRABP1

Proteins

cellular retinoic acid-binding protein 1
Refseq ID NP_004369
Protein GI 4758052
UniProt ID P29762
mRNA ID NM_004378
Length 137
RefSeq Status REVIEWED
MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE

Gene Information

Entrez Gene ID
1381
Gene Name
cellular retinoic acid binding protein 1
Gene Symbol
CRABP1
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0001972 IEA:Ensembl F retinoic acid binding
GO:0005215 IEA:InterPro F transporter activity

REACTOME Pathway Links

REACTOME Pathway ID Description
REACT_11082 Import of palmitoyl-CoA into the mitochondrial matrix
REACT_2071 Pyruvate metabolism
REACT_12528 Regulation of pyruvate dehydrogenase (PDH) complex

Domain Information

InterPro Annotations

Accession Description
IPR012674 Calycin
IPR011038 Calycin-like
IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain

UniProt Annotations

Entry Information

Gene Name
cellular retinoic acid binding protein 1
Protein Entry
RABP1_HUMAN
UniProt ID
P29762
Species
Human

Identical and Related Proteins

Unique RefSeq proteins for LMP002610 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
4758052 RefSeq NP_004369 137 cellular retinoic acid-binding protein 1

Identical Sequences to LMP002610 proteins

Reference Database Accession Length Protein Name
GI:4758052 RefSeq XP_007173502.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Balaenoptera acutorostrata scammoni]
GI:4758052 RefSeq XP_007471912.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Lipotes vexillifer]
GI:4758052 RefSeq XP_008013910.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Chlorocebus sabaeus]
GI:4758052 RefSeq XP_008052508.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Tarsius syrichta]
GI:4758052 RefSeq XP_008531041.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Equus przewalskii]
GI:4758052 RefSeq XP_010381454.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Rhinopithecus roxellana]

Related Sequences to LMP002610 proteins

Reference Database Accession Length Protein Name
GI:4758052 EMBL CAG33298.1 137 CRABP1 [Homo sapiens]
GI:4758052 GenBank ACM84940.1 162 Sequence 10438 from patent US 6812339
GI:4758052 RefSeq XP_003784605.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Otolemur garnettii]
GI:4758052 RefSeq XP_004403659.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Odobenus rosmarus divergens]
GI:4758052 RefSeq XP_004421925.1 137 PREDICTED: cellular retinoic acid-binding protein 1 [Ceratotherium simum simum]
GI:4758052 RefSeq XP_008572750.1 137 PREDICTED: cellular retinoic acid-binding protein 1 isoform X1 [Galeopterus variegatus]