Gene/Proteome Database (LMPD)

LMPD ID
LMP002673
Gene ID
13177
Species
Mus musculus (Mouse)
Gene Name
enoyl-Coenzyme A delta isomerase 1
Gene Symbol
Eci1
Synonyms
Dci; eci
Alternate Names
enoyl-CoA delta isomerase 1, mitochondrial; dodecenoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; 3,2 trans-enoyl-Coenyme A isomerase; delta(3),Delta(2)-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase, mitochondrial; dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase)
Chromosome
17
Map Location
17 A3.3|17
EC Number
5.3.3.8

Proteins

enoyl-CoA delta isomerase 1, mitochondrial precursor
Refseq ID NP_034153
Protein GI 31981810
UniProt ID P42125
mRNA ID NM_010023
Length 289
RefSeq Status VALIDATED
MALAAARRLLLHAGSRLGRREAVDGARRFANKRVLVETEGPAGVAVMKLRNPPVNSLSLECLTEFTISLEKLENDKSIRGVILTSECPGIFSAGLDLLEMYGRNPAHYAEYWKNVQELWLRLYTSNMILVSAINGASPAGGCLLALCCDYRVMADNPKYTIGLNESLLGIVAPFWFKDMYVNTIGHREAERALQLGTLFSPAEALKVGVVDEVVPEDQVHSKARSVMTKWLAIPDHSRQLTKNMMRKATADNLIKQREADIQNFTSFISKDSIQKSLHMYLEKLKQKKG
transit_peptide: 1..28 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (P42125.2) calculated_mol_wt: 3045 peptide sequence: MALAAARRLLLHAGSRLGRREAVDGARR mat_peptide: 29..289 product: Enoyl-CoA delta isomerase 1, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P42125.2) calculated_mol_wt: 29224 peptide sequence: FANKRVLVETEGPAGVAVMKLRNPPVNSLSLECLTEFTISLEKLENDKSIRGVILTSECPGIFSAGLDLLEMYGRNPAHYAEYWKNVQELWLRLYTSNMILVSAINGASPAGGCLLALCCDYRVMADNPKYTIGLNESLLGIVAPFWFKDMYVNTIGHREAERALQLGTLFSPAEALKVGVVDEVVPEDQVHSKARSVMTKWLAIPDHSRQLTKNMMRKATADNLIKQREADIQNFTSFISKDSIQKSLHMYLEKLKQKKG

Gene Information

Entrez Gene ID
13177
Gene Name
enoyl-Coenzyme A delta isomerase 1
Gene Symbol
Eci1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005743 IDA:MGI C mitochondrial inner membrane
GO:0005739 IDA:MGI C mitochondrion
GO:0004165 IDA:MGI F dodecenoyl-CoA delta-isomerase activity
GO:0006635 IMP:MGI P fatty acid beta-oxidation

KEGG Pathway Links

KEGG Pathway ID Description
mmu00071 Fatty acid degradation

REACTOME Pathway Links

REACTOME Pathway ID Description
5893028 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids

Domain Information

InterPro Annotations

Accession Description
IPR029045 ClpP/crotonase-like domain
IPR001753 Crotonase_core_superfam
IPR018376 Enoyl-CoA hydratase/isomerase, conserved site

UniProt Annotations

Entry Information

Gene Name
enoyl-Coenzyme A delta isomerase 1
Protein Entry
ECI1_MOUSE
UniProt ID
P42125
Species
Mouse

Comments

Comment Type Description
Catalytic Activity (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl- CoA.
Function Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
Pathway Lipid metabolism; fatty acid beta-oxidation.
Similarity Belongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular Location Mitochondrion matrix.
Subunit Homotrimer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP002673 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31981810 RefSeq NP_034153 289 enoyl-CoA delta isomerase 1, mitochondrial precursor

Identical Sequences to LMP002673 proteins

Reference Database Accession Length Protein Name
GI:31981810 DBBJ BAC26469.1 289 unnamed protein product [Mus musculus]
GI:31981810 GenBank AAH22712.1 289 Dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase) [Mus musculus]
GI:31981810 GenBank AAH54444.1 289 Dci protein [Mus musculus]
GI:31981810 GenBank EDL22317.1 289 dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase) [Mus musculus]
GI:31981810 SwissProt P42125.2 289 RecName: Full=Enoyl-CoA delta isomerase 1, mitochondrial; AltName: Full=3,2-trans-enoyl-CoA isomerase; AltName: Full=Delta(3),Delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Dodecenoyl-CoA isomerase; Flags: Precursor [Mus musculus]

Related Sequences to LMP002673 proteins

Reference Database Accession Length Protein Name
GI:31981810 DBBJ BAB23605.1 289 unnamed protein product [Mus musculus]
GI:31981810 EMBL CAA78417.1 289 dodecenoyl-CoA delta-isomerase [Mus musculus]
GI:31981810 EMBL CAA78418.1 289 dodecenoyl-CoA delta isomerase [Mus musculus]
GI:31981810 GenBank AEU53486.1 289 Sequence 117 from patent US 8062891
GI:31981810 GenBank AGU32430.1 289 Sequence 117 from patent US 8507277
GI:31981810 PRF - 289 enoyl-CoA isomerase [Mus musculus]