Gene/Proteome Database (LMPD)

LMPD ID
LMP002743
Gene ID
18107
Species
Mus musculus (Mouse)
Gene Name
N-myristoyltransferase 1
Gene Symbol
Nmt1
Synonyms
AW536594
Alternate Names
glycylpeptide N-tetradecanoyltransferase 1; NMT 1; type I N-myristoyltransferase; peptide N-myristoyltransferase 1; myristoyl-CoA:protein N-myristoyltransferase 1
Chromosome
11
Map Location
11|11 D
EC Number
2.3.1.97

Proteins

glycylpeptide N-tetradecanoyltransferase 1
Refseq ID NP_032733
Protein GI 6679082
UniProt ID O70310
mRNA ID NM_008707
Length 496
RefSeq Status PROVISIONAL
MADESETAVKLPAPSLPLMMEGNGNGHEHCSDCENEEDNSHNRSGLSPANDTGAKKKKKKQKKKKEKGSDMESTQDQPVKMTSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMEKKDIPVVHQLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ

Gene Information

Entrez Gene ID
18107
Gene Name
N-myristoyltransferase 1
Gene Symbol
Nmt1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0015629 IEA:Ensembl C actin cytoskeleton
GO:0030054 IEA:Ensembl C cell junction
GO:0005737 TAS:MGI C cytoplasm
GO:0005886 IEA:Ensembl C plasma membrane
GO:0004379 IMP:MGI F glycylpeptide N-tetradecanoyltransferase activity
GO:0001701 IMP:MGI P in utero embryonic development
GO:0018008 ISA:MGI P N-terminal peptidyl-glycine N-myristoylation
GO:0006499 IMP:MGI P N-terminal protein myristoylation

REACTOME Pathway Links

REACTOME Pathway ID Description
5893169 Activation, myristolyation of BID and translocation to mitochondria
5892893 Inactivation, recovery and regulation of the phototransduction cascade
5893142 Intrinsic Pathway for Apoptosis
5892890 Visual phototransduction

Domain Information

InterPro Annotations

Accession Description
IPR016181 Acyl-CoA N-acyltransferase
IPR000903 Myristoyl-CoA:protein N-myristoyltransferase
IPR022678 Myristoyl-CoA:protein N-myristoyltransferase, conserved site
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal

UniProt Annotations

Entry Information

Gene Name
N-myristoyltransferase 1
Protein Entry
NMT1_MOUSE
UniProt ID
O70310
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Tetradecanoyl-CoA + glycylpeptide = CoA + N- tetradecanoylglycylpeptide.
Function Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
Similarity Belongs to the NMT family. {ECO:0000305}.
Subcellular Location Cytoplasm.

Identical and Related Proteins

Unique RefSeq proteins for LMP002743 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6679082 RefSeq NP_032733 496 glycylpeptide N-tetradecanoyltransferase 1

Identical Sequences to LMP002743 proteins

Reference Database Accession Length Protein Name
GI:6679082 DBBJ BAE27232.1 496 unnamed protein product [Mus musculus]
GI:6679082 GenBank AAC09296.1 496 N-myristoyltransferase 1 [Mus musculus]
GI:6679082 GenBank AAH16526.1 496 N-myristoyltransferase 1 [Mus musculus]
GI:6679082 GenBank AAH21635.1 496 N-myristoyltransferase 1 [Mus musculus]
GI:6679082 RefSeq XP_006532508.1 496 PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 isoform X1 [Mus musculus]
GI:6679082 SwissProt O70310.1 496 RecName: Full=Glycylpeptide N-tetradecanoyltransferase 1; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 1; Short=NMT 1; Short=Type I N-myristoyltransferase; AltName: Full=Peptide N-myristoyltransferase 1 [Mus musculus]

Related Sequences to LMP002743 proteins

Reference Database Accession Length Protein Name
GI:6679082 EMBL CAD37349.1 496 peptide N-myristoyltransferase 1 [Rattus norvegicus]
GI:6679082 GenBank AAH97277.1 496 N-myristoyltransferase 1 [Rattus norvegicus]
GI:6679082 GenBank EDM06248.1 496 N-myristoyltransferase 1, isoform CRA_b [Rattus norvegicus]
GI:6679082 RefSeq NP_683689.1 496 glycylpeptide N-tetradecanoyltransferase 1 [Rattus norvegicus]
GI:6679082 RefSeq XP_005369141.1 496 PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 [Microtus ochrogaster]
GI:6679082 SwissProt Q8K1Q0.1 496 RecName: Full=Glycylpeptide N-tetradecanoyltransferase 1; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 1; Short=NMT 1; Short=Type I N-myristoyltransferase; AltName: Full=Peptide N-myristoyltransferase 1 [Rattus norvegicus]