Gene/Proteome Database (LMPD)

LMPD ID
LMP002790
Gene ID
14815
Species
Mus musculus (Mouse)
Gene Name
nuclear receptor subfamily 3, group C, member 1
Gene Symbol
Nr3c1
Synonyms
GR; Grl-1; Grl1
Chromosome
18
Map Location
18 B3|18 21.09 cM

Proteins

glucocorticoid receptor
Refseq ID NP_032199
Protein GI 121247453
UniProt ID E9PUR6
mRNA ID NM_008173
Length 792
RefSeq Status VALIDATED
MDSKESLAPPGRDEVPSSLLGRGRGSVMDLYKTLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSASNAQQQQQQQQQQQQQQQQQPQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSRPENPKSSTPAAGCATPTEKEFPQTHSDPSSEQQNRKSQPGTNGGSVKLYTTDQSTFDILQDLEFSAGSPGKETNESPWRSDLLIDENLLSPLAGEDDPFLLEGDVNEDCKPLILPDTKPKIQDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK

Gene Information

Entrez Gene ID
14815
Gene Name
nuclear receptor subfamily 3, group C, member 1
Gene Symbol
Nr3c1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:MGI C cytoplasm
GO:0005829 IDA:MGI C cytosol
GO:0005622 IDA:MGI C intracellular
GO:0016020 IDA:MGI C membrane
GO:0005634 IDA:MGI C nucleus
GO:0003677 IDA:MGI F DNA binding
GO:0004883 IDA:MGI F glucocorticoid receptor activity
GO:0046983 IDA:MGI F protein dimerization activity
GO:0043565 IDA:MGI F sequence-specific DNA binding
GO:0003700 IEA:InterPro F sequence-specific DNA binding transcription factor activity
GO:0005496 IEA:InterPro F steroid binding
GO:0008270 IEA:InterPro F zinc ion binding
GO:0030325 IMP:MGI P adrenal gland development
GO:0008211 IMP:MGI P glucocorticoid metabolic process
GO:0042921 IDA:MGI P glucocorticoid receptor signaling pathway
GO:0060603 IMP:MGI P mammary gland duct morphogenesis
GO:0042711 IGI:MGI P maternal behavior
GO:1900170 IDA:MGI P negative regulation of glucocorticoid mediated signaling pathway
GO:0043525 IGI:MGI P positive regulation of neuron apoptotic process
GO:0031946 IMP:MGI P regulation of glucocorticoid biosynthetic process
GO:0006111 IMP:MGI P regulation of gluconeogenesis
GO:0006355 IDA:MGI P regulation of transcription, DNA-templated
GO:0006351 IEA:UniProtKB-KW P transcription, DNA-templated

Domain Information

InterPro Annotations

Accession Description
IPR001409 Glucocorticoid receptor
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
nuclear receptor subfamily 3, group C, member 1
Protein Entry
E9PUR6_MOUSE
UniProt ID
E9PUR6
Species
Mouse

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP002790 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
121247453 RefSeq NP_032199 792 glucocorticoid receptor

Identical Sequences to LMP002790 proteins

Reference Database Accession Length Protein Name
GI:121247453 RefSeq XP_006525729.1 792 PREDICTED: glucocorticoid receptor isoform X9 [Mus musculus]

Related Sequences to LMP002790 proteins

Reference Database Accession Length Protein Name
GI:121247453 RefSeq XP_006525722.1 793 PREDICTED: glucocorticoid receptor isoform X2 [Mus musculus]
GI:121247453 RefSeq XP_006525723.1 793 PREDICTED: glucocorticoid receptor isoform X3 [Mus musculus]
GI:121247453 RefSeq XP_006525724.1 793 PREDICTED: glucocorticoid receptor isoform X4 [Mus musculus]
GI:121247453 RefSeq XP_006525725.1 793 PREDICTED: glucocorticoid receptor isoform X5 [Mus musculus]
GI:121247453 RefSeq XP_006525726.1 793 PREDICTED: glucocorticoid receptor isoform X6 [Mus musculus]
GI:121247453 RefSeq XP_006525727.1 793 PREDICTED: glucocorticoid receptor isoform X7 [Mus musculus]