Gene/Proteome Database (LMPD)

LMPD ID
LMP002961
Gene ID
71365
Species
Mus musculus (Mouse)
Gene Name
prenyl (solanesyl) diphosphate synthase, subunit 2
Gene Symbol
Pdss2
Synonyms
5430420P03Rik; Gm60; Plmp; kd; mDLP1
Alternate Names
decaprenyl-diphosphate synthase subunit 2; solanesyl-diphosphate synthase subunit 2; decaprenyl pyrophosphate synthase subunit 2; prenyltransferase-like mitochondrial protein; decaprenyl pyrophosphate synthetase subunit 2; all-trans-decaprenyl-diphosphate synthase subunit 2
Chromosome
10
Map Location
10 B2|10 22.91 cM
EC Number
2.5.1.91

Proteins

decaprenyl-diphosphate synthase subunit 2 isoform 1
Refseq ID NP_082048
Protein GI 269973903
UniProt ID Q33DR3
mRNA ID NM_027772
Length 401
RefSeq Status VALIDATED
MSLRQLLLRLSGYLGASGPPSRHWWYFRSLDSISSAGSWRGRSSRSPAHWNQVVSEAEKIVGYPASFMSLRCLLSDELSNIAMQVRKLVGTGHPLLTTARALVHDSRHNLQLRGLVVLLISKAAGPSTRNAACQNYDMVSGVYSCQRSLAEITELIHTALLVHRGIVNLSELQSSDGPLKDMQFGNKIAILSGDFLLANACNGLALLQNTKVVELLSSALMDLVHGVYQENSASTKENSIPDDIGISTWKEQTFLSHCALLAKSCQAAMELAKHDAAVQDMAFQYGKHMAMSHKINADLQPFIKDKASDSKTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGSLNYSKLRETIKAGKGVTSAIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS
decaprenyl-diphosphate synthase subunit 2 isoform 2
Refseq ID NP_001161761
Protein GI 269973905
UniProt ID Q33DR3
mRNA ID NM_001168289
Length 352
RefSeq Status VALIDATED
MSLRQLLLRLSGYLGASGPPSRHWWYFRSLDSISSAGSWRGRSSRSPAHWNQVVSEAEKIVGYPASFMSLRCLLSDELSNIAMQVRKLVGTGHPLLTTARALVHDSRHNLQLRGLVVLLISKAAGPSTRNAACQNYDMVSGVYSCQRSLAEITELIHTALLVHRGIVNLSELQSSDGPLKDMQFGNKIAILSGDFLLANACNGLALLQNTKVVELLSSALMDLVHGVYQENSASTKENSIPDDIGISTWKEQTFLSHCALLAKSCQAAMELAKHDAAVQDMAFQYGKHMAMSHKINADLQPFIKDKASDSKTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGSLNYSKVVS

Gene Information

Entrez Gene ID
71365
Gene Name
prenyl (solanesyl) diphosphate synthase, subunit 2
Gene Symbol
Pdss2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:MGI C mitochondrion
GO:0046982 IDA:HGNC F protein heterodimerization activity
GO:0000010 IEA:Ensembl F trans-hexaprenyltranstransferase activity
GO:0008299 IDA:HGNC P isoprenoid biosynthetic process
GO:0051290 IPI:MGI P protein heterotetramerization
GO:0050878 IMP:MGI P regulation of body fluid levels
GO:0006744 IDA:HGNC P ubiquinone biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00900 Terpenoid backbone biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5894069 Ubiquinol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR008949 Isoprenoid synthase domain
IPR000092 Polyprenyl synthetase
IPR017446 Polyprenyl synthetase-related

UniProt Annotations

Entry Information

Gene Name
prenyl (solanesyl) diphosphate synthase, subunit 2
Protein Entry
DLP1_MOUSE
UniProt ID
Q33DR3
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q33DR3-1; Sequence=Displayed; Name=2; IsoId=Q33DR3-2; Sequence=VSP_017104, VSP_017105; Note=No experimental confirmation available.; Name=3; IsoId=Q33DR3-3; Sequence=VSP_017102, VSP_017103;
Catalytic Activity (2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate. {ECO:0000269|PubMed:16262699}.
Function Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. {ECO:0000269|PubMed:16262699}.
Pathway Cofactor biosynthesis; ubiquinone biosynthesis.
Similarity Belongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000305}.
Subunit Heterotetramer of 2 DPS1/TPRT and 2 DLP1 subunits. {ECO:0000269|PubMed:16262699}.

Identical and Related Proteins

Unique RefSeq proteins for LMP002961 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
269973903 RefSeq NP_082048 401 decaprenyl-diphosphate synthase subunit 2 isoform 1
269973905 RefSeq NP_001161761 352 decaprenyl-diphosphate synthase subunit 2 isoform 2

Identical Sequences to LMP002961 proteins

Reference Database Accession Length Protein Name
GI:269973905 DBBJ BAE24234.1 352 unnamed protein product [Mus musculus]
GI:269973903 GenBank AAI47694.1 401 Prenyl (solanesyl) diphosphate synthase, subunit 2 [Mus musculus]
GI:269973903 GenBank AAI47695.1 401 Prenyl (solanesyl) diphosphate synthase, subunit 2 [Mus musculus]
GI:269973903 RefSeq XP_006512914.1 401 PREDICTED: decaprenyl-diphosphate synthase subunit 2 isoform X1 [Mus musculus]
GI:269973903 SwissProt Q33DR3.2 401 RecName: Full=Decaprenyl-diphosphate synthase subunit 2; AltName: Full=All-trans-decaprenyl-diphosphate synthase subunit 2; AltName: Full=Decaprenyl pyrophosphate synthase subunit 2; AltName: Full=Solanesyl-diphosphate synthase subunit 2 [Mus musculus]

Related Sequences to LMP002961 proteins

Reference Database Accession Length Protein Name
GI:269973903 DBBJ BAE48218.1 401 subunit 2 of solanesyl diphosphate synthase [Mus musculus]
GI:269973903 GenBank AAH85898.1 401 Prenyl (decaprenyl) diphosphate synthase, subunit 2 [Rattus norvegicus]
GI:269973905 GenBank AAI47694.1 401 Prenyl (solanesyl) diphosphate synthase, subunit 2 [Mus musculus]
GI:269973905 GenBank AAI47695.1 401 Prenyl (solanesyl) diphosphate synthase, subunit 2 [Mus musculus]
GI:269973903 GenBank ACH16309.1 401 Sequence 6 from patent US 7402413
GI:269973905 GenBank ACH16309.1 401 Sequence 6 from patent US 7402413
GI:269973903 GenBank AFL00054.1 401 Sequence 6 from patent US 8163525
GI:269973903 RefSeq NP_001014271.1 401 decaprenyl-diphosphate synthase subunit 2 [Rattus norvegicus]
GI:269973905 RefSeq NP_082048.2 401 decaprenyl-diphosphate synthase subunit 2 isoform 1 [Mus musculus]
GI:269973905 RefSeq XP_006512914.1 401 PREDICTED: decaprenyl-diphosphate synthase subunit 2 isoform X1 [Mus musculus]
GI:269973903 SwissProt Q5U2R1.1 401 RecName: Full=Decaprenyl-diphosphate synthase subunit 2; AltName: Full=All-trans-decaprenyl-diphosphate synthase subunit 2; AltName: Full=Decaprenyl pyrophosphate synthase subunit 2 [Rattus norvegicus]
GI:269973905 SwissProt Q33DR3.2 401 RecName: Full=Decaprenyl-diphosphate synthase subunit 2; AltName: Full=All-trans-decaprenyl-diphosphate synthase subunit 2; AltName: Full=Decaprenyl pyrophosphate synthase subunit 2; AltName: Full=Solanesyl-diphosphate synthase subunit 2 [Mus musculus]